Th17 cells: a new paradigm for cutaneous inflammation (Q37217449)

19 August 2017

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title

Th17 cells: a new paradigm for cutaneous inflammation (English)

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19 August 2017

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Adam Asarch

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19 August 2017

Orr Barak

series ordinal

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19 August 2017

Daniel S Loo

series ordinal

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19 August 2017

Alice B Gottlieb

series ordinal

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19 August 2017

publication date

1 January 2008

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Journal of Dermatological Treatment

19 August 2017

published in

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19 August 2017

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19 August 2017

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19 August 2017

page(s)

259-266

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A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage

19 August 2017

cites work

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Differentiation and function of Th17 T cells

21 January 2018

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Expanding the effector CD4 T-cell repertoire: the Th17 lineage.

21 January 2018

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Th17: an effector CD4 T cell lineage with regulatory T cell ties

21 January 2018

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

21 January 2018

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Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12

21 January 2018

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A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R

21 January 2018

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Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation

21 January 2018

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https://api.crossref.org/works/10.1080%2F09546630802206686

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

21 January 2018

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IL-12 and IL-23: master regulators of innate and adaptive immunity.

21 January 2018

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Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis

21 January 2018

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Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation

21 January 2018

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A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Transforming growth factor-beta induces development of the T(H)17 lineage

21 January 2018

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Immunopathogenesis of psoriasis

21 January 2018

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Immunopathogenesis and role of T cells in psoriasis

21 January 2018

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https://api.crossref.org/works/10.1080%2F09546630802206686

Pathophysiology of psoriasis: recent advances on IL-23 and Th17 cytokines

21 January 2018

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Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

21 January 2018

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https://api.crossref.org/works/10.1080%2F09546630802206686

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

21 January 2018

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Divergent effects of IL-12 and IL-23 on the production of IL-17 by human T cells

21 January 2018

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The function of interleukin 17 in the pathogenesis of rheumatoid arthritis

21 January 2018

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The IL-23/Th(17) axis: therapeutic targets for autoimmune inflammation

21 January 2018

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After interleukin-12p40, are interleukin-23 and interleukin-17 the next therapeutic targets for inflammatory bowel disease?

21 January 2018

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https://api.crossref.org/works/10.1080%2F09546630802206686

Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis

21 January 2018

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https://api.crossref.org/works/10.1080%2F09546630802206686

Interleukin-17 and interferon-gamma synergize in the enhancement of proinflammatory cytokine production by human keratinocytes.

21 January 2018

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https://api.crossref.org/works/10.1080%2F09546630802206686

Interleukin-17 in inflammatory skin disorders

21 January 2018

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https://api.crossref.org/works/10.1080%2F09546630802206686

A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

An anti-IL-12p40 antibody down-regulates type 1 cytokines, chemokines, and IL-12/IL-23 in psoriasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Safety and efficacy of ABT-874, a fully human interleukin 12/23 monoclonal antibody, in the treatment of moderate to severe chronic plaque psoriasis: results of a randomized, placebo-controlled, phase 2 trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

IL-17 family cytokines and the expanding diversity of effector T cell lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Inhibition of interleukin-17 prevents the development of arthritis in vaccinated mice challenged with Borrelia burgdorferi

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

IL-23 is increased in dendritic cells in multiple sclerosis and down-regulation of IL-23 by antisense oligos increases dendritic cell IL-10 production

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

The IL23 axis plays a key role in the pathogenesis of IBD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Th17: the third member of the effector T cell trilogy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

T cells doing it for themselves: TGF-beta regulation of Th1 and Th17 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Three decades of psoriasis research: where has it led us?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

IL-22 increases the innate immunity of tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Expression and regulation of IL-22 in the IL-17-producing CD4+ T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Development, cytokine profile and function of human interleukin 17-producing helper T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

TGFbeta1, a "Jack of all trades": the link with pro-inflammatory IL-17-producing T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Polarized in vivo expression of IL-11 and IL-17 between acute and chronic skin lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Latent TGFbeta1 overexpression in keratinocytes results in a severe psoriasis-like skin disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

In vitro reproduction of clinical hallmarks of eczematous dermatitis in organotypic skin models

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Wound-healing factors secreted by epidermal keratinocytes and dermal fibroblasts in skin substitutes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Dendritic cell-derived IL-15 controls the induction of CD8 T cell immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Resolution of psoriasis upon blockade of IL-15 biological activity in a xenograft mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Interleukin-15: a new cytokine target for the treatment of inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Signal transduction pathways and transcriptional regulation in the control of Th17 differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

IL-23 production by cosecretion of endogenous p19 and transgenic p40 in keratin 14/p40 transgenic mice: evidence for enhanced cutaneous immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

In vitro and in situ expression of IL-23 by keratinocytes in healthy skin and psoriasis lesions: enhanced expression in psoriatic skin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

Microbial lipopeptides induce the production of IL-17 in Th cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F09546630802206686

10.1080/09546630802206686

21 January 2018

Identifiers

DOI

1 reference

19 August 2017

1 reference