Caenorhabditits elegans LRK-1 and PINK-1 act antagonistically in stress response and neurite outgrowth (Q37269214)

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scientific article published on 27 February 2009

Caenorhabditits elegansLRK-1 and PINK-1 Act Antagonistically in Stress Response and Neurite Outgrowth

Language	Label	Description	Also known as
English	Caenorhabditits elegans LRK-1 and PINK-1 act antagonistically in stress response and neurite outgrowth	scientific article published on 27 February 2009	Caenorhabditits elegansLRK-1 and PINK-1 Act Antagonistically in Stress Response and Neurite Outgrowth

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Caenorhabditits elegans LRK-1 and PINK-1 act antagonistically in stress response and neurite outgrowth (English)

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Caenorhabditis elegans

0 references

Serine/threonine-protein kinase pink-1, mitochondrial CELE_EEED8.9

1 reference

GOA release 2020-03-11

Leucine-rich repeat serine/threonine-protein kinase 1 CELE_T27C10.6

1 reference

GOA release 2020-03-11

1 reference

based on heuristic

inferred from title

author name string

Julia Sämann

1

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Jan Hegermann

2

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Erika von Gromoff

3

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Stefan Eimer

4

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Ralf Baumeister

5

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Enrico Schmidt

6

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

language of work or name

0 references

publication date

27 February 2009

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

284

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

24

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

16482-16491

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

Loss of PINK1 causes mitochondrial functional defects and increased sensitivity to oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

6 September 2017

The kinase domain of mitochondrial PINK1 faces the cytoplasm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

6 September 2017

LRRK2 regulates synaptic vesicle endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

6 September 2017

Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

6 September 2017

Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

6 September 2017

PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

6 September 2017

LRRK2 phosphorylates moesin at threonine-558: characterization of how Parkinson's disease mutants affect kinase activity

1 reference

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6 September 2017

Leucine-rich repeat kinase 2 associates with lipid rafts

1 reference

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Localization of LRRK2 to membranous and vesicular structures in mammalian brain

1 reference

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6 September 2017

The familial Parkinsonism gene LRRK2 regulates neurite process morphology

1 reference

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6 September 2017

Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

6 September 2017

PINK1 protein in normal human brain and Parkinson's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

6 September 2017

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

6 September 2017

Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin

1 reference

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Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets

1 reference

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6 September 2017

Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

6 September 2017

Mutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

6 September 2017

Hereditary early-onset Parkinson's disease caused by mutations in PINK1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

6 September 2017

C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span

1 reference

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The use of lead citrate at high pH as an electron-opaque stain in electron microscopy

1 reference

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6 September 2017

A novel cGMP signalling pathway mediating myosin phosphorylation and chemotaxis in Dictyostelium

1 reference

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6 September 2017

Rab proteins as membrane organizers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

6 September 2017

Identification of Caenorhabditis elegans Genes Required for Neuronal Differentiation and Migration

1 reference

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6 September 2017

Novel inhibitory action of tunicamycin homologues suggests a role for dynamic protein fatty acylation in growth cone-mediated neurite extension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

6 September 2017

Mutations in the clk-1 gene of Caenorhabditis elegans affect developmental and behavioral timing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

6 September 2017

The genetics of Caenorhabditis elegans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

6 September 2017

RNA interference of LRRK2-microarray expression analysis of a Parkinson's disease key player

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

14 September 2017

Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

14 September 2017

Pink1 Parkinson mutations, the Cdc37/Hsp90 chaperones and Parkin all influence the maturation or subcellular distribution of Pink1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

14 September 2017

Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

14 September 2017

Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

14 September 2017

Loss of LRRK2/PARK8 induces degeneration of dopaminergic neurons in Drosophila.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

3 September 2018

LRK-1, a C. elegans PARK8-related kinase, regulates axonal-dendritic polarity of SV proteins

1 reference

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Analysis of synaptic ultrastructure without fixative using high-pressure freezing and tomography.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

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Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

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A Caenorhabditis elegans Parkin mutant with altered solubility couples alpha-synuclein aggregation to proteotoxic stress

1 reference

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Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease.

1 reference

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Distinct rac activation pathways control Caenorhabditis elegans cell migration and axon outgrowth

1 reference

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Three C. elegans Rac proteins and several alternative Rac regulators control axon guidance, cell migration and apoptotic cell phagocytosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2713553

3 September 2018

Toxicity of tunicamycin to cultured brain neurons: ultrastructure of the degenerating neurons

1 reference

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Rapid arrest of axon elongation by brefeldin A: a role for the small GTP-binding protein ARF in neuronal growth cones.

1 reference

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Axonal and neuronal amyloid precursor protein immunoreactivity in the brains of guinea pigs given tunicamycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19251702

12 December 2020

based on heuristic

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Inhibition of dynamic protein palmitoylation in intact cells with tunicamycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/19251702

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M808255200

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

19 August 2017

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