The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complex (Q37048390)

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scientific article published on 14 June 2013

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English	The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complex	scientific article published on 14 June 2013

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scholarly article

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Europe PubMed Central

PMC publication ID

17 August 2017

The small GTPase RALA controls c-Jun N-terminal kinase-mediated FOXO activation by regulation of a JIP1 scaffold complex (English)

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17 August 2017

Tobias B Dansen

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Tobias B Dansen

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Maaike C W van den Berg

1

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17 August 2017

Inkie J A van Gogh

2

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17 August 2017

Alida M M Smits

3

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17 August 2017

Miranda van Triest

4

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17 August 2017

Marieke Visscher

6

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17 August 2017

Paulien E Polderman

7

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17 August 2017

Marjolein J Vliem

8

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17 August 2017

Holger Rehmann

9

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17 August 2017

Boudewijn M T Burgering

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17 August 2017

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14 June 2013

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Journal of Biological Chemistry

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17 August 2017

288

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17 August 2017

30

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17 August 2017

21729-21741

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17 August 2017

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3724631/fullTextXML

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FOXOs: signalling integrators for homeostasis maintenance

1 reference

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Redox regulation of Ras and Rho GTPases: mechanism and function

1 reference

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S-nitrosylation of mixed lineage kinase 3 contributes to its activation after cerebral ischemia

1 reference

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Ras effector switching promotes divergent cell fates in C. elegans vulval patterning

1 reference

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FoxO and stress responses in the cnidarian Hydra vulgaris

1 reference

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Redox control of GTPases: from molecular mechanisms to functional significance in health and disease

1 reference

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FoxO transcription factors in the maintenance of cellular homeostasis during aging

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JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16.

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RalA interacts with ZONAB in a cell density-dependent manner and regulates its transcriptional activity

1 reference

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29 September 2017

FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK.

1 reference

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MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation

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FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1)

1 reference

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Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals

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Akt2 Negatively Regulates Assembly of the POSH-MLK-JNK Signaling Complex

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RAL GTPases are linchpin modulators of human tumour-cell proliferation and survival

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JNK-interacting protein 1 promotes Akt1 activation.

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Negative regulation of mixed lineage kinase 3 by protein kinase B/AKT leads to cell survival

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Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

1 reference

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Akt1 regulates a JNK scaffold during excitotoxic apoptosis

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Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38

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Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation

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Requirement of the JIP1 scaffold protein for stress-induced JNK activation

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3724631

29 September 2017

Ras-dependent regulation of c-Jun phosphorylation is mediated by the Ral guanine nucleotide exchange factor-Ral pathway

1 reference

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Ral GTPases contribute to regulation of cyclin D1 through activation of NF-kappaB.

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Species- and cell type-specific requirements for cellular transformation

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Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family

1 reference

https://pubmed.ncbi.nlm.nih.gov/23770673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of 12-O-tetradecanoylphorbol-13-acetate response element- and dyad symmetry element-dependent transcription by interleukin-5 is mediated by Jun N-terminal kinase/stress-activated protein kinase kinases

1 reference

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based on heuristic

inferred from PubMed ID database lookup

The exocyst is a Ral effector complex

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https://pubmed.ncbi.nlm.nih.gov/23770673

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Synergistic activation of SAPK1/JNK1 by two MAP kinase kinases in vitro

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https://pubmed.ncbi.nlm.nih.gov/23770673

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M113.463885

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

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