Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease (Q36959352)

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scientific article published on November 2004

Language	Label	Description	Also known as
English	Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease	scientific article published on November 2004

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease (English)

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Europe PubMed Central

PMC publication ID

17 August 2017

Huntington's disease

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1 reference

based on heuristic

inferred from title

object named as

Hoon Ryu

2

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object named as

Brett Langley

15

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Sandra J. Hewett

object named as

Sandra Hewett

13

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Robert J Ferrante

1

object named as

Robert J Ferrante

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Europe PubMed Central

PMC publication ID

17 August 2017

10

object named as

M Flint Beal

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Europe PubMed Central

PMC publication ID

17 August 2017

Bruce S Kristal

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object named as

Bruce S Kristal

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Europe PubMed Central

PMC publication ID

17 August 2017

author name string

James K Kubilus

3

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Europe PubMed Central

PMC publication ID

17 August 2017

Santosh D'Mello

4

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Europe PubMed Central

PMC publication ID

17 August 2017

Katharine L Sugars

5

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Europe PubMed Central

PMC publication ID

17 August 2017

Junghee Lee

6

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Europe PubMed Central

PMC publication ID

17 August 2017

Peiyuan Lu

7

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Europe PubMed Central

PMC publication ID

17 August 2017

Karen Smith

8

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Europe PubMed Central

PMC publication ID

17 August 2017

Susan Browne

9

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Europe PubMed Central

PMC publication ID

17 August 2017

Irina G Stavrovskaya

12

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17 August 2017

David C Rubinsztein

14

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17 August 2017

Rajiv R Ratan

16

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Europe PubMed Central

PMC publication ID

17 August 2017

language of work or name

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publication date

1 November 2004

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Europe PubMed Central

PMC publication ID

17 August 2017

Journal of Neuroscience

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Europe PubMed Central

PMC publication ID

17 August 2017

24

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PMC publication ID

17 August 2017

46

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17 August 2017

10335-10342

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Europe PubMed Central

PMC publication ID

17 August 2017

CCAAT displacement protein/cut homolog recruits G9a histone lysine methyltransferase to repress transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

Minocycline inhibits contusion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

Linking the epigenetic 'language' of covalent histone modifications to cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

Histone methyltransferases direct different degrees of methylation to define distinct chromatin domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

Minocycline inhibits caspase-independent and -dependent mitochondrial cell death pathways in models of Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

Histone deacetylase inhibitors prevent oxidative neuronal death independent of expanded polyglutamine repeats via an Sp1-dependent pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

Interaction of Huntington disease protein with transcriptional activator Sp1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

Transcriptional dysregulation in Huntington's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

The mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which downmodulates p21WAF1/CIP1/SDI1 in S phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

Functional analysis of the Huntington's disease (HD) gene promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

The human cut homeodomain protein represses transcription from the c-myc promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

Interaction of the CCAAT displacement protein with shared regulatory elements required for transcription of paired histone genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

Alternative excitotoxic hypotheses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

29 September 2017

Sp1 and Sp3 Are Oxidative Stress-Inducible, Antideath Transcription Factors in Cortical Neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

27 June 2018

Expression of beta-galactosidase under the control of the human c-myc promoter in transgenic mice is inhibited by mithramycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

27 June 2018

CCAAT displacement protein as a repressor of the myelomonocytic-specific gp91-phox gene promoter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

27 June 2018

Histone Deacetylase Inhibition by Sodium Butyrate Chemotherapy Ameliorates the Neurodegenerative Phenotype in Huntington's Disease Mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

4 September 2018

Neurodegeneration. A glutamine-rich trail leads to transcription factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

4 September 2018

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

4 September 2018

Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

4 September 2018

Sequence-selective DNA binding drugs mithramycin A and chromomycin A3 are potent inhibitors of neuronal apoptosis induced by oxidative stress and DNA damage in cortical neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

4 September 2018

A microtiter trypan blue absorbance assay for the quantitative determination of excitotoxic neuronal injury in cell culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2577231

4 September 2018

Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/15548647

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional repression of the cystic fibrosis transmembrane conductance regulator gene, mediated by CCAAT displacement protein/cut homolog, is associated with histone deacetylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15548647

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptogenic ganglioside GD3 directly induces the mitochondrial permeability transition

1 reference

https://pubmed.ncbi.nlm.nih.gov/15548647

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased apoptosis of Huntington disease lymphoblasts associated with repeat length-dependent mitochondrial depolarization

1 reference

https://pubmed.ncbi.nlm.nih.gov/15548647

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.2599-04.2004

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 August 2017

ResearchGate publication ID

0 references

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