Extensive Random Mutagenesis Analysis of the Na+/K+‐ATPase α Subunit Identifies Known and Previously Unidentified Amino Acid Residues that Alter Ouabain Sensitivity Implications for Ouabain Binding (Q36888091)

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scientific article published on September 1, 1997

Language	Label	Description	Also known as
English	Extensive Random Mutagenesis Analysis of the Na+/K+‐ATPase α Subunit Identifies Known and Previously Unidentified Amino Acid Residues that Alter Ouabain Sensitivity Implications for Ouabain Binding	scientific article published on September 1, 1997

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

Extensive random mutagenesis analysis of the Na+/K+-ATPase alpha subunit identifies known and previously unidentified amino acid residues that alter ouabain sensitivity--implications for ouabain binding (English)

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

Extensive Random Mutagenesis Analysis of the Na+/K+‐ATPase α Subunit Identifies Known and Previously Unidentified Amino Acid Residues that Alter Ouabain Sensitivity Implications for Ouabain Binding (English)

1 reference

10.1111/J.1432-1033.1997.00488.X

https://api.crossref.org/works/10.1111/J.1432-1033.1997.00488.X

21 November 2024

author name string

M. L. Croyle

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9346307

21 November 2024

A. L. Woo

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9346307

21 November 2024

J. B. Lingrel

3

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21 November 2024

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publication date

1 September 1997

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16 August 2017

full work available at URL

https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1432-1033.1997.00488.x

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online access status

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A9346307

21 November 2024

https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1432-1033.1997.00488.x

1 reference

10.1111/J.1432-1033.1997.00488.X

https://api.crossref.org/works/10.1111/J.1432-1033.1997.00488.X

21 November 2024

https://febs.onlinelibrary.wiley.com/doi/pdf/10.1111/j.1432-1033.1997.00488.x

1 reference

10.1111/J.1432-1033.1997.00488.X

https://api.crossref.org/works/10.1111/J.1432-1033.1997.00488.X

21 November 2024

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

248

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Europe PubMed Central

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16 August 2017

2

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Europe PubMed Central

PubMed publication ID

16 August 2017

488-495

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Europe PubMed Central

PubMed publication ID

16 August 2017

Substitutions of serine 775 in the alpha subunit of the Na,K-ATPase selectively disrupt K+ high affinity activation without affecting Na+ interaction.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1432-1033.1997.00488.X

21 January 2018

Asp804 and Asp808 in the transmembrane domain of the Na,K-ATPase alpha subunit are cation coordinating residues

1 reference

https://api.crossref.org/works/10.1111%2FJ.1432-1033.1997.00488.X

21 January 2018

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1 reference

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21 January 2018

Endoplasmic reticulum form of calreticulin modulates glucocorticoid-sensitive gene expression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1432-1033.1997.00488.X

21 January 2018

Ouabain-resistant mutants of the rat Na,K-ATPase alpha 2 isoform identified by using an episomal expression vector

1 reference

https://api.crossref.org/works/10.1111%2FJ.1432-1033.1997.00488.X

21 January 2018

Ouabain-receptor interactions in (Na+ + K+)-ATPase preparations. II. Effect of cations and nucleotides on rate constants and dissociation constants

1 reference

https://api.crossref.org/works/10.1111%2FJ.1432-1033.1997.00488.X

21 January 2018

Substitution of glutamic 779 with alanine in the Na,K-ATPase alpha subunit removes voltage dependence of ion transport

4

1 reference

10.1111/J.1432-1033.1997.00488.X

https://api.crossref.org/works/10.1111/J.1432-1033.1997.00488.X

21 November 2024

Random mutagenesis of the sheep Na,K-ATPase alpha1 subunit generating the ouabain-resistant mutant L793P.

11

1 reference

10.1111/J.1432-1033.1997.00488.X

https://api.crossref.org/works/10.1111/J.1432-1033.1997.00488.X

21 November 2024

Randomization of genes by PCR mutagenesis

12

1 reference

10.1111/J.1432-1033.1997.00488.X

https://api.crossref.org/works/10.1111/J.1432-1033.1997.00488.X

21 November 2024

Mutation of a cysteine in the first transmembrane segment of Na,K-ATPase alpha subunit confers ouabain resistance

13

1 reference

10.1111/J.1432-1033.1997.00488.X

https://api.crossref.org/works/10.1111/J.1432-1033.1997.00488.X

21 November 2024

Analysis of amino acid residues in the H5-H6 transmembrane and extracellular domains of Na,K-ATPase alpha subunit identifies threonine 797 as a determinant of ouabain sensitivity

19

1 reference

10.1111/J.1432-1033.1997.00488.X

https://api.crossref.org/works/10.1111/J.1432-1033.1997.00488.X

21 November 2024

The amino-terminal 200 amino acids of the plasma membrane Na+,K+-ATPase alpha subunit confer ouabain sensitivity on the sarcoplasmic reticulum Ca(2+)-ATPase

22

1 reference

10.1111/J.1432-1033.1997.00488.X

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21 November 2024

Rapid and efficient site-specific mutagenesis without phenotypic selection

27

1 reference

10.1111/J.1432-1033.1997.00488.X

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21 November 2024

An improved assay for nanomole amounts of inorganic phosphate

29

1 reference

10.1111/J.1432-1033.1997.00488.X

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21 November 2024

Membrane disposition of the M5-M6 hairpin of Na+,K(+)-ATPase alpha subunit is ligand dependent.

34

1 reference

10.1111/J.1432-1033.1997.00488.X

https://api.crossref.org/works/10.1111/J.1432-1033.1997.00488.X

21 November 2024

Identification of the amino acids comprising a surface-exposed epitope within the nucleotide-binding domain of the Na+,K(+)-ATPase using a random peptide library

35

1 reference

10.1111/J.1432-1033.1997.00488.X

https://api.crossref.org/works/10.1111/J.1432-1033.1997.00488.X

21 November 2024

Ouabain interactions with the H5-H6 hairpin of the Na,K-ATPase reveal a possible inhibition mechanism via the cation binding domain

36

1 reference

10.1111/J.1432-1033.1997.00488.X

https://api.crossref.org/works/10.1111/J.1432-1033.1997.00488.X

21 November 2024

Structure-function relationships in the Na,K-ATPase alpha subunit: site-directed mutagenesis of glutamine-111 to arginine and asparagine-122 to aspartic acid generates a ouabain-resistant enzyme

37

1 reference

10.1111/J.1432-1033.1997.00488.X

https://api.crossref.org/works/10.1111/J.1432-1033.1997.00488.X

21 November 2024

Substitution of transmembrane residues with hydrogen-bonding potential in the .alpha. subunit of sodium-potassium ATPase reveals alterations in ouabain sensitivity

41

1 reference

10.1111/J.1432-1033.1997.00488.X

https://api.crossref.org/works/10.1111/J.1432-1033.1997.00488.X

21 November 2024

Identifiers

10.1111/J.1432-1033.1997.00488.X

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

16 August 2017

ResearchGate publication ID

0 references

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