IMPDH activity in thiopurine-treated patients with inflammatory bowel disease - relation to TPMT activity and metabolite concentrations (Q36535994)

From Wikidata

Jump to navigation Jump to search

The printable version is no longer supported and may have rendering errors. Please update your browser bookmarks and please use the default browser print function instead.

scientific article published on 27 July 2007

Language	Label	Description	Also known as
English	IMPDH activity in thiopurine-treated patients with inflammatory bowel disease - relation to TPMT activity and metabolite concentrations	scientific article published on 27 July 2007

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

IMPDH activity in thiopurine-treated patients with inflammatory bowel disease - relation to TPMT activity and metabolite concentrations (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

inflammatory bowel diseases

0 references

4

object named as

Sven Almer

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

author name string

Sofie Haglund

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Jan Taipalensuu

2

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Curt Peterson

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

0 references

publication date

27 July 2007

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

British Journal of Clinical Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

65

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

69-77

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

IMPDH1 promoter mutations in a patient exhibiting azathioprine resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

Validation and application of a high-performance liquid chromatographic-based assay for determination of the inosine 5'-monophosphate dehydrogenase activity in erythrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

Pharmacogenetics during standardised initiation of thiopurine treatment in inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

Thiopurine therapies: problems, complexities, and progress with monitoring thioguanine nucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

Mutation in the ITPA gene predicts intolerance to azathioprine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

Maintenance therapy for inflammatory bowel disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

Therapeutic drug monitoring of azathioprine and 6-mercaptopurine metabolites in Crohn disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

Steroid-dependent Crohn's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

Assignment1 of inosine '-monophosphate dehydrogenase type 2 (IMPDH2) to human chromosome band 3p21.2 by in situ hybridization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

A simple clinical colitis activity index

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

A review of immune modifier therapy for inflammatory bowel disease: azathioprine, 6-mercaptopurine, cyclosporine, and methotrexate.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

The accumulation of mercaptopurine metabolites in age fractionated red blood cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

Tissue-differential expression of two distinct genes for human IMP dehydrogenase (E.C.1.1.1.205).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

Human type I and II IMP dehydrogenases as drug targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

Biochemical strategy of cancer cells and the design of chemotherapy: G. H. A. Clowes Memorial Lecture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

A simple index of Crohn's-disease activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

Symposium on immunosuppressive drugs. Biochemistry and pharmacology of purine analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

Two distinct cDNAs for human IMP dehydrogenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

Increased inosine-5'-phosphate dehydrogenase gene expression in solid tumor tissues and tumor cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

Human liver thiopurine methyltransferase pharmacogenetics: biochemical properties, liver-erythrocyte correlation and presence of isozymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

Incorporation of analog purine nucleosides into the formed elements of human blood: erythrocytes, platelets, and lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

IMP dehydrogenase, an enzyme linked with proliferation and malignancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

30 September 2017

Inosine-5'-monophosphate dehydrogenase: regulation of expression and role in cellular proliferation and T lymphocyte activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

28 June 2018

On the paradoxically concentration-dependent metabolism of 6-mercaptopurine in WEHI-3b murine leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

28 June 2018

Induction of cell differentiation in melanoma cells by inhibitors of IMP dehydrogenase: altered patterns of IMP dehydrogenase expression and activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

28 June 2018

Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: a meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

21 September 2018

Inosine triphosphate pyrophosphatase and thiopurine s-methyltransferase genotypes relationship to azathioprine-induced myelosuppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

21 September 2018

ITPA genotyping is not predictive for the development of side effects in AZA treated inflammatory bowel disease patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

21 September 2018

Association of inosine triphosphatase 94C>A and thiopurine S-methyltransferase deficiency with adverse events and study drop-outs under azathioprine therapy in a prospective Crohn disease study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

21 September 2018

ITPA genotyping test does not improve detection of Crohn's disease patients at risk of azathioprine/6-mercaptopurine induced myelosuppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

21 September 2018

Assessment of thiopurine methyltransferase and metabolite formation during thiopurine therapy: results from a large Swedish patient population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

21 September 2018

Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

21 September 2018

Selective inhibition of inflammatory gene expression in activated T lymphocytes: a mechanism of immune suppression by thiopurines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

21 September 2018

Distribution of ITPA P32T alleles in multiple world populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

21 September 2018

Adverse drug reactions to azathioprine therapy are associated with polymorphism in the gene encoding inosine triphosphate pyrophosphatase (ITPase).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

21 September 2018

Identification of two novel sequence variants affecting thiopurine methyltransferase enzyme activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

21 September 2018

Determination of thiopurine methyltransferase activity in isolated human erythrocytes does not reflect putative in vivo enzyme inhibition by sulfasalazine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

21 September 2018

Leucocyte versus erythrocyte thioguanine nucleotide concentrations in children taking thiopurines for acute lymphoblastic leukaemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

21 September 2018

Differences between children and adults in thiopurine methyltransferase activity and metabolite formation during thiopurine therapy: possible role of concomitant methotrexate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

21 September 2018

6-MP metabolite profiles provide a biochemical explanation for 6-MP resistance in patients with inflammatory bowel disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

21 September 2018

Non-radioactive determination of inosine 5'-monophosphate dehydro-genase (IMPDH) in peripheral mononuclear cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

21 September 2018

6-Mercaptopurine: Cytotoxicity and biochemical pharmacology in human malignant T-lymphoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

21 September 2018

Demonstration of induction of erythrocyte inosine monophosphate dehydrogenase activity in Ribavirin-treated patients using a high performance liquid chromatography linked method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2291267

21 September 2018

Formation and significance of 6-methylthiopurine ribonucleotide as a metabolite of 6-mercaptopurine

1 reference

https://pubmed.ncbi.nlm.nih.gov/17662091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro metabolism of 6-mercaptopurine by human liver cytosol

1 reference

https://pubmed.ncbi.nlm.nih.gov/17662091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chromosomal localization and structure of the human type II IMP dehydrogenase gene (IMPDH2)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17662091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Individualizing therapy with 6-mercaptopurine and 6-thioguanine related to the thiopurine methyltransferase genetic polymorphism

1 reference

https://pubmed.ncbi.nlm.nih.gov/17662091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of phosphoribosyl pyrophosphate amidotransferase from Ehrlich ascites-tumour cells by thiopurine nucleotides

1 reference

https://pubmed.ncbi.nlm.nih.gov/17662091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patterns of azathioprine metabolites in neutrophils, lymphocytes, reticulocytes, and erythrocytes: relevance to toxicity and monitoring in recipients of renal allografts

1 reference

https://pubmed.ncbi.nlm.nih.gov/17662091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacogenetics of thiopurine therapy in paediatric IBD patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17662091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and properties of 5-phosphoribosyl pyrophosphate amidotransferase from adenocarcinoma 755 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17662091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship between thiopurine methyltransferase activity and genotype in blasts from patients with acute leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17662091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiopurine methyltransferase biochemical genetics: human lymphocyte activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17662091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Medical therapy for ulcerative colitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17662091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphic thiopurine methyltransferase in erythrocytes is indicative of activity in leukemic blasts from children with acute lymphoblastic leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17662091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of 6-thioguanine in peripheral blood leukocyte DNA in Crohn's disease patients on maintenance 6-mercaptopurine therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/17662091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-performance liquid chromatographic assay of the methyl and nucleotide metabolites of 6-mercaptopurine: quantitation of red blood cell 6-thioguanine nucleotide, 6-thioinosinic acid and 6-methylmercaptopurine metabolites in a single sample

1 reference

https://pubmed.ncbi.nlm.nih.gov/17662091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Assignment of the human type I IMP dehydrogenase gene (IMPDH1) to chromosome 7q31.3-q32)

1 reference

https://pubmed.ncbi.nlm.nih.gov/17662091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic variation in response to 6-mercaptopurine for childhood acute lymphoblastic leukaemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/17662091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Therapy for Crohn disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17662091

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1365-2125.2007.02985.X

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q36535994&oldid=1637340427"