Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and application of statins as a novel effective therapeutic approach against Acanthamoeba infections (Q36505318)

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scientific article published on 31 October 2012

Language	Label	Description	Also known as
English	Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and application of statins as a novel effective therapeutic approach against Acanthamoeba infections	scientific article published on 31 October 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and application of statins as a novel effective therapeutic approach against Acanthamoeba infections (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

object named as

Brendan Loftus

7

0 references

José E. Piñero

object named as

José E Piñero

10

0 references

Jacob Lorenzo-Morales

object named as

Jacob Lorenzo-Morales

2

0 references

Atteneri López-Arencibia

object named as

Atteneri López-Arencibia

4

0 references

author name string

Carmen María Martín-Navarro

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Rubén P Machin

3

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

José Manuel García-Castellano

5

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Isabel de Fuentes

6

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Sutherland K Maciver

8

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Basilio Valladares

9

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

language of work or name

0 references

publication date

31 October 2012

1 reference

Europe PubMed Central

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14 August 2017

Antimicrobial Agents and Chemotherapy

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Europe PubMed Central

PMC publication ID

14 August 2017

57

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

375-381

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

Structure-based design and screen of novel inhibitors for class II 3-hydroxy-3-methylglutaryl coenzyme A reductase from Streptococcus pneumoniae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535909

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The differential effects of statins on the metastatic behaviour of prostate cancer.

1 reference

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30 September 2017

Targeting tumor cell metabolism with statins.

1 reference

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30 September 2017

Biology and pathogenesis of Acanthamoeba

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535909

30 September 2017

Statins and their influence on brain cholesterol

1 reference

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MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

1 reference

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30 September 2017

Low doses of simvastatin therapy ameliorate cardiac inflammatory remodeling in Trypanosoma cruzi-infected dogs.

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30 September 2017

Therapeutic potential of a combination of two gene-specific small interfering RNAs against clinical strains of Acanthamoeba

1 reference

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Atorvastatin as a potential anti-malarial drug: in vitro synergy in combinational therapy with quinine against Plasmodium falciparum

1 reference

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Acanthamoeba castellanii Neff: In vitro activity against the trophozoite stage of a natural sesquiterpene and a synthetic cobalt(II)-lapachol complex

1 reference

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30 September 2017

Statins as potential antimalarial drugs: low relative potency and lack of synergy with conventional antimalarial drugs

1 reference

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30 September 2017

The potential pathogenicity of chlorhexidine-sensitive Acanthamoeba strains isolated from contact lens cases from asymptomatic individuals in Tenerife, Canary Islands, Spain

1 reference

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30 September 2017

Efficacy of contact lens systems against recent clinical and tap water Acanthamoeba isolates

1 reference

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30 September 2017

Comparison of polyhexamethylene biguanide and chlorhexidine as monotherapy agents in the treatment of Acanthamoeba keratitis

1 reference

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30 September 2017

Acanthamoeba: biology and increasing importance in human health

1 reference

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Universal behavior of membranes with sterols.

1 reference

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30 September 2017

Potential applications for RNAi to probe pathogenesis and develop new treatments for ocular disorders

1 reference

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30 September 2017

Development of colorimetric microtiter plate assay for assessment of antimicrobials against Acanthamoeba

1 reference

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30 September 2017

Chemical, pharmacokinetic and pharmacodynamic properties of statins: an update

1 reference

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30 September 2017

Free-living amoebae as opportunistic and non-opportunistic pathogens of humans and animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535909

30 September 2017

Pathogenesis of Acanthamoeba infections

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535909

30 September 2017

Acanthamoebaspp. as Agents of Disease in Humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535909

30 September 2017

Structural mechanism for statin inhibition of HMG-CoA reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535909

30 September 2017

Primer3 on the WWW for general users and for biologist programmers

1 reference

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30 September 2017

Mevinolin (lovastatin) potentiates the antiproliferative effects of ketoconazole and terbinafine against Trypanosoma (Schizotrypanum) cruzi: in vitro and in vivo studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535909

30 September 2017

3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors lovastatin and simvastatin inhibit in vitro development of Plasmodium falciparum and Babesia divergens in human erythrocytes

1 reference

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Sterol biosynthesis de nova via cycloartenol by the soil amoeba Acanthamoeba polyphaga

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Characterization and regulation of Leishmania major 3-hydroxy-3-methylglutaryl-CoA reductase.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3535909

28 June 2018

Sterols of Acanthamoeba culbertsoni strain A-1.

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28 June 2018

Influence of long-term treatment with pravastatin on the survival, evolution of cutaneous lesion and weight of animals infected by Leishmania amazonensis.

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Statins alone are ineffective in cerebral malaria but potentiate artesunate

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Simvastatin treatment shows no effect on the incidence of cerebral malaria or parasitemia during experimental malaria

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Acanthamoeba keratitis: persistent organisms without inflammation after 1 year of topical chlorhexidine

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21 September 2018

RNA interference (RNAi) for the silencing of extracellular serine proteases genes in Acanthamoeba: molecular analysis and effect on pathogenecity.

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Antischistosomal action of atorvastatin alone and concurrently with medroxyprogesterone acetate on Schistosoma haematobium harboured in hamster: surface ultrastructure and parasitological study.

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Changes in the lipid composition and activities of isocitrate dehydrogenase and isocitrate lyase during encystation of Acanthamoeba culbertsoni strain A-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/23114753

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7-Dehydrostigmasterol and ergosterol: the major sterols of an amoeba

1 reference

https://pubmed.ncbi.nlm.nih.gov/23114753

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inferred from PubMed ID database lookup

Growth inhibition of Candida species and Aspergillus fumigatus by statins

1 reference

https://pubmed.ncbi.nlm.nih.gov/23114753

12 December 2020

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inferred from PubMed ID database lookup

Antischistosomal action of mevinolin: evidence that 3-hydroxy-methylglutaryl-coenzyme a reductase activity in Schistosoma mansoni is vital for parasite survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/23114753

12 December 2020

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Synergism in vitro of lovastatin and miconazole as anti-leishmanial agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/23114753

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Statins inhibit Toxoplasma gondii multiplication in macrophages in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/23114753

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/AAC.01426-12

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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