ABCB1 genotype and PGP expression, function and therapeutic drug response: a critical review and recommendations for future research. (Q36592129)

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scientific article published on 12 September 2006

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English	ABCB1 genotype and PGP expression, function and therapeutic drug response: a critical review and recommendations for future research.	scientific article published on 12 September 2006

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scholarly article

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30 December 2019

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Europe PubMed Central

ABCB1 genotype and PGP expression, function and therapeutic drug response: a critical review and recommendations for future research (English)

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30 December 2019

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30 December 2019

Munir Pirmohamed

3

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30 December 2019

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Leschziner GD

1

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30 December 2019

Johnson MR

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30 December 2019

publication date

12 September 2006

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30 December 2019

The Pharmacogenomics Journal

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30 December 2019

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30 December 2019

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30 December 2019

154-179

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Relationship between the C3435T and G2677T(A) polymorphisms in the ABCB1 gene and P-glycoprotein expression in human liver

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Drug-drug interaction mediated by inhibition and induction of P-glycoprotein

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MDR1 Ala893 polymorphism is associated with inflammatory bowel disease

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MDR1 genotypes do not influence the absorption of a single oral dose of 1 mg digoxin in healthy white males

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Role of human MDR1 gene polymorphism in bioavailability and interaction of digoxin, a substrate of P-glycoprotein.

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The MDR1 polymorphisms at exons 21 and 26 predict steroid weaning in pediatric heart transplant patients

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The effect of CYP3A5 and MDR1 (ABCB1) polymorphisms on cyclosporine and tacrolimus dose requirements and trough blood levels in stable renal transplant patients

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Impact of CYP3A5 and MDR1(ABCB1) C3435T polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients

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Influence of CYP3A5 and MDR1 (ABCB1) polymorphisms on the pharmacokinetics of tacrolimus in renal transplant recipients

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C3435T mutation in exon 26 of the human MDR1 gene and cyclosporine pharmacokinetics in healthy subjects.

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Consequences of genetic polymorphisms for sirolimus requirements after renal transplant in patients on primary sirolimus therapy

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Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4, and CYP3A5 genes.

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Control of confounding of genetic associations in stratified populations

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Statistical significance for genomewide studies

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Carbamazepine is not a substrate for P-glycoprotein

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Association study designs for complex diseases

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On the allelic spectrum of human disease

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The future of genetic studies of complex human diseases

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Logistic regression protects against population structure in genetic association studies

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An utter refutation of the "fundamental theorem of the HapMap".

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Digoxin pharmacokinetics and MDR1 genetic polymorphisms

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Association of Multidrug Resistance in Epilepsy with a Polymorphism in the Drug-Transporter GeneABCB1

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Human MDR1 polymorphism: G2677T/A and C3435T have no effect on MDR1 transport activities

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Intestinal inflammation induces adaptation of P-glycoprotein expression and activity

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Modulation of steady-state kinetics of digoxin by haplotypes of the P-glycoprotein MDR1 gene

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MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects

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Guidelines for association studies in Human Molecular Genetics

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MDR1 C3435T genetic polymorphism does not influence the response to antiretroviral therapy in drug-naive HIV-positive patients

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Failure to confirm association of a polymorphism in ABCB1 with multidrug-resistant epilepsy

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Association of an ABCB1 gene haplotype with pharmacoresistance in temporal lobe epilepsy

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Association of 5' CpG demethylation and altered chromatin structure in the promoter region with transcriptional activation of the multidrug resistance 1 gene in human cancer cells

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In vitro translation of a 2.3-kb splicing variant of the hamster pgp1 gene whose presence in transfectants is associated with decreased drug resistance

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Identification of polymorphisms on the MDR1 gene among Turkish population and their effects on multidrug resistance in acute leukemia patients

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Linkage disequilibrium mapping of complex disease: fantasy or reality?

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7 January 2021

based on heuristic

inferred from DOI database lookup

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