Protein folding and conformational stress in microbial cells producing recombinant proteins: a host comparative overview (Q36569895)

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scientific article published on 4 April 2008

Language	Label	Description	Also known as
English	Protein folding and conformational stress in microbial cells producing recombinant proteins: a host comparative overview	scientific article published on 4 April 2008

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

1 reference

Europe PubMed Central

Protein folding and conformational stress in microbial cells producing recombinant proteins: a host comparative overview (English)

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

protein folding

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3

object named as

Ursula Rinas

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Martin Dragosits

object named as

Martin Dragosits

4

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Brigitte Gasser

object named as

Brigitte Gasser

1

0 references

object named as

Pau Ferrer

12

0 references

Maria Luisa Tutino

object named as

Maria Luisa Tutino

13

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Ermenegilda Parrilli

object named as

Ermenegilda Parrilli

8

0 references

Diethard Mattanovich

object named as

Diethard Mattanovich

14

0 references

Antonio Villaverde

object named as

Antonio Villaverde

15

0 references

author name string

Markku Saloheimo

2

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Escarlata Rodríguez-Carmona

5

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Kristin Baumann

6

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Maria Giuliani

7

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Paola Branduardi

9

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Christine Lang

10

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Danilo Porro

11

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

publication date

4 April 2008

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Microbial Cell Factories

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

7

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Divergent genetic control of protein solubility and conformational quality in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

ERADicate ER stress or die trying

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Tipping the delicate balance: defining how proteasome maturation affects the degradation of a substrate for autophagy and endoplasmic reticulum associated degradation (ERAD).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Transcriptomics-based identification of novel factors enhancing heterologous protein secretion in yeasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Increase of calnexin gene dosage boosts the secretion of heterologous proteins by Hansenula polymorpha

1 reference

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30 September 2017

Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Chaperone-based procedure to increase yields of soluble recombinant proteins produced in E. coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Signal integration in the endoplasmic reticulum unfolded protein response

1 reference

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30 September 2017

Genomic analysis of the secretion stress response in the enzyme-producing cell factory Aspergillus niger

1 reference

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30 September 2017

Process technology for production and recovery of heterologous proteins with Pichia pastoris

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Expression and assembly of a functional type IV secretion system elicit extracytoplasmic and cytoplasmic stress responses in Escherichia coli

1 reference

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30 September 2017

Inclusion body anatomy and functioning of chaperone-mediated in vivo inclusion body disassembly during high-level recombinant protein production in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

The chaperone DnaK controls the fractioning of functional protein between soluble and insoluble cell fractions in inclusion body-forming cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

A flow cytometric assay for screening improved heterologous protein secretion in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Overview of bacterial expression systems for heterologous protein production: from molecular and biochemical fundamentals to commercial systems

1 reference

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30 September 2017

Applications of cell sorting in biotechnology

1 reference

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30 September 2017

Production of soluble and active transferrin receptor-targeting single-chain antibody using Saccharomyces cerevisiae

1 reference

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30 September 2017

Common features and interesting differences in transcriptional responses to secretion stress in the fungi Trichoderma reesei and Saccharomyces cerevisiae

1 reference

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30 September 2017

Persistent glycoprotein misfolding activates the glucosidase II/UGT1-driven calnexin cycle to delay aggregation and loss of folding competence

1 reference

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30 September 2017

Saccharomyces cerevisiae adaptation to weak acids involves the transcription factor Haa1p and Haa1p-regulated genes.

1 reference

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30 September 2017

Coping with cold: the genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125

1 reference

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30 September 2017

Aggregation as bacterial inclusion bodies does not imply inactivation of enzymes and fluorescent proteins

1 reference

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30 September 2017

ERAD: the long road to destruction

1 reference

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30 September 2017

Cloning, expression and characterisation of a single-chain Fv antibody fragment against domoic acid in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Lon and ClpP proteases participate in the physiological disintegration of bacterial inclusion bodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Effect of increased expression of protein disulfide isomerase and heavy chain binding protein on antibody secretion in a recombinant CHO cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Transcriptome analysis of recombinant protein secretion by Aspergillus nidulans and the unfolded-protein response in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Localization of chaperones DnaK and GroEL in bacterial inclusion bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Bioprocessing strategies to improve heterologous protein production in filamentous fungal fermentations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Soluble expression of recombinant proteins in the cytoplasm of Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Differential gene expression in recombinant Pichia pastoris analysed by heterologous DNA microarray hybridisation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Advanced genetic strategies for recombinant protein expression in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Quality control in the bacterial periplasm

1 reference

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30 September 2017

Catalysis of disulfide bond formation and isomerization in the Escherichia coli periplasm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Recombinant protein folding and misfolding in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Stress in recombinant protein producing yeasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Bottlenecks in the expression and secretion of heterologous proteins in Bacillus subtilis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Modulation of Aspergillus awamori thaumatin secretion by modification of bipA gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Strategies for the recovery of active proteins through refolding of bacterial inclusion body proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Prokaryotic expression of antibodies and affibodies.

1 reference

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30 September 2017

The effect of hyperosmotic pressure on antibody production and gene expression in the GS-NS0 cell line

1 reference

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30 September 2017

Recombinant protein production in Antarctic Gram-negative bacteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Protein folding and quality control in the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Roles of heat-shock chaperones in the production of recombinant proteins in Escherichia coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Stress induced by recombinant protein production in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Structure of Ero1p, source of disulfide bonds for oxidative protein folding in the cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Protein quality control in the bacterial periplasm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Oxidative protein folding in eukaryotes: mechanisms and consequences

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Protein disulfide isomerase, but not binding protein, overexpression enhances secretion of a non-disulfide-bonded protein in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Yeast Golgi apparatus--dynamics and sorting.

1 reference

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30 September 2017

Molecular chaperones: structure of a protein disaggregase

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30 September 2017

The transcription factor HACA mediates the unfolded protein response in Aspergillus niger, and up-regulates its own transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Improvement of foreign-protein production in Aspergillus niger var. awamori by constitutive induction of the unfolded-protein response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Protein aggregation in recombinant bacteria: biological role of inclusion bodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Novel insights into the osmotic stress response of yeast

1 reference

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30 September 2017

Effects of inactivation and constitutive expression of the unfolded- protein response pathway on protein production in the yeast Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Calnexin co-expression and the use of weaker promoters increase the expression of correctly assembled Shaker potassium channel in insect cells

1 reference

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30 September 2017

Activation mechanisms of the HAC1-mediated unfolded protein response in filamentous fungi

1 reference

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30 September 2017

Decreased protein expression and intermittent recoveries in BiP levels result from cellular stress during heterologous protein expression in Saccharomyces cerevisiae.

1 reference

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30 September 2017

Prevention and reversion of protein aggregation by molecular chaperones in the E. coli cytosol: implications for their applicability in biotechnology

1 reference

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30 September 2017

Construction and deconstruction of bacterial inclusion bodies

1 reference

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30 September 2017

Impaired cutinase secretion in Saccharomyces cerevisiae induces irregular endoplasmic reticulum (ER) membrane proliferation, oxidative stress, and ER-associated degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Calnexin overexpression increases manganese peroxidase production in Aspergillus niger

1 reference

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30 September 2017

XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor

1 reference

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30 September 2017

The unfolding tale of the unfolded protein response

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30 September 2017

Block of HAC1 mRNA translation by long-range base pairing is released by cytoplasmic splicing upon induction of the unfolded protein response

1 reference

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30 September 2017

Translocation of proteins across the cell envelope of Gram-positive bacteria

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30 September 2017

Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation

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30 September 2017

Intracellular signaling from the endoplasmic reticulum to the nucleus: the unfolded protein response in yeast and mammals

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30 September 2017

Genomic expression programs in the response of yeast cells to environmental changes

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30 September 2017

Monitoring of genes that respond to overproduction of an insoluble recombinant protein in Escherichia coli glucose-limited fed-batch fermentations.

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30 September 2017

Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

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30 September 2017

The heat shock response of Escherichia coli.

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30 September 2017

Efficient folding of proteins with multiple disulfide bonds in the Escherichia coli cytoplasm

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30 September 2017

Evaluation of bottlenecks in the late stages of protein secretion in Bacillus subtilis.

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30 September 2017

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

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30 September 2017

Expression of active human tissue-type plasminogen activator in Escherichia coli.

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30 September 2017

Disulfide bond formation in the Escherichia coli cytoplasm: an in vivo role reversal for the thioredoxins

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30 September 2017

Expression and secretion of defined cutinase variants by Aspergillus awamori.

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30 September 2017

Chaperone coexpression plasmids: differential and synergistic roles of DnaK-DnaJ-GrpE and GroEL-GroES in assisting folding of an allergen of Japanese cedar pollen, Cryj2, in Escherichia coli

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30 September 2017

The response to extracytoplasmic stress in Escherichia coli is controlled by partially overlapping pathways

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30 September 2017

Recombinant protein expression at low temperatures under the transcriptional control of the major Escherichia coli cold shock promoter cspA.

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30 September 2017

tRNA ligase is required for regulated mRNA splicing in the unfolded protein response

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30 September 2017

A novel mechanism for regulating activity of a transcription factor that controls the unfolded protein response

1 reference

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30 September 2017

Reduction of BiP levels decreases heterologous protein secretion in Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase

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30 September 2017

Overexpression of bacterial hemoglobin causes incorporation of pre-beta-lactamase into cytoplasmic inclusion bodies

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30 September 2017

Regulation of the Escherichia coli heat-shock response.

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30 September 2017

Saccharomyces cerevisiae CNE1 encodes an endoplasmic reticulum (ER) membrane protein with sequence similarity to calnexin and calreticulin and functions as a constituent of the ER quality control apparatus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Isolation and characterization of Bacillus subtilis groE regulatory mutants: evidence for orf39 in the dnaK operon as a repressor gene in regulating the expression of both groE and dnaK

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Constitutive overexpression of secreted heterologous proteins decreases extractable BiP and protein disulfide isomerase levels in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Factors influencing inclusion body formation in the production of a fused protein in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Protein folding in the cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Gene expression in yeast: protein secretion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Protein aggregation in vitro and in vivo: a quantitative model of the kinetic competition between folding and aggregation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Two novel heat shock genes encoding proteins produced in response to heterologous protein expression in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

30 September 2017

Effect of cultivating conditions on alpha-galactosidase production by a novel Aspergillus foetidus ZU-G1 strain in solid-state fermentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

28 June 2018

A novel high-throughput screen reveals yeast genes that increase secretion of heterologous proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

28 June 2018

Effect of media composition and growth conditions on production of beta-glucosidase by Aspergillus niger C-6.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

28 June 2018

Cell viability and secretion of active proteins in Schizosaccharomyces pombe do not require the chaperone function of calnexin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

28 June 2018

Effect of doxycycline-regulated calnexin and calreticulin expression on specific thrombopoietin productivity of recombinant Chinese hamster ovary cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

28 June 2018

Optimal conditions for the expression of a single-chain antibody (scFv) gene in Pichia pastoris

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

28 June 2018

Lipid modification of prelipoproteins is dispensable for growth but essential for efficient protein secretion in Bacillus subtilis: characterization of the Lgt gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

28 June 2018

Increasing the secretory capacity of Saccharomyces cerevisiae for production of single-chain antibody fragments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

28 June 2018

Molecular chaperones, folding catalysts, and the recovery of active recombinant proteins fromE. coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

28 June 2018

Overexpression of binding protein and disruption of the PMR1 gene synergistically stimulate secretion of bovine prochymosin but not plant thaumatin in yeast.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

28 June 2018

Protein disulfide isomerase mutant lacking its isomerase activity accelerates protein folding in the cell.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

28 June 2018

The levels of endoplasmic reticulum proteins and ATP affect folding and secretion of selective proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

28 June 2018

Protein composition of Vitreoscilla hemoglobin inclusion bodies produced in Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

28 June 2018

Protein compositional analysis of inclusion bodies produced in recombinant Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

28 June 2018

The cold-active Lip1 lipase from the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125 is a member of a new bacterial lipolytic enzyme family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Hypoxic fed-batch cultivation of Pichia pastoris increases specific and volumetric productivity of recombinant proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Protocol for preparing proteins with improved solubility by co-expressing with molecular chaperones in Escherichia coli.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Transcriptional response of P. pastoris in fed-batch cultivations to Rhizopus oryzae lipase production reveals UPR induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Role of the chaperone DnaK in protein solubility and conformational quality in inclusion body-forming Escherichia coli cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Enhancing the production of Fc fusion protein in fed-batch fermentation of Pichia pastoris by design of experiments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Expression of Cu, Zn-superoxide dismutase gene from Saccharomyces cerevisiae in Pichia pastoris and its resistance to oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Fermentation process for tetrameric human collagen prolyl 4-hydroxylase in Escherichia coli: improvement by gene optimisation of the PDI/beta subunit and repeated addition of the inducer anhydrotetracycline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Cooverexpression of chaperones for enhanced secretion of a single-chain antibody fragment in Pichia pastoris

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

The evaluation of the factors that cause aggregation during recombinant expression in E. coli is simplified by the employment of an aggregation-sensitive reporter.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Induced fit of passenger proteins fused to Archaea maltose binding proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Engineering of Pichia pastoris for improved production of antibody fragments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Improvement of cell viability and hirudin production by ascorbic acid in Pichia pastoris fermentation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Functional expression of single-chain variable fragment antibody against c-Met in the cytoplasm of Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Enhancement of protein secretion in Pichia pastoris by overexpression of protein disulfide isomerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Elevated expression temperature in a mesophilic host results in increased secretion of a hyperthermophilic enzyme and decreased cell stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Secretion of human serum albumin by Kluyveromyces lactis overexpressing KlPDI1 and KlERO1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Folding of a misfolding-prone beta-galactosidase in absence of DnaK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Amyloid-like properties of bacterial inclusion bodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Engineering of a Pichia pastoris expression system for secretion of high amounts of intact human parathyroid hormone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Efficient secretion of human lysozyme from the yeast, Kluyveromyces lactis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

The effect of specific growth rate on protein synthesis and secretion in the filamentous fungus Trichoderma reesei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Endoplasmic reticulum stress leads to the selective transcriptional downregulation of the glucoamylase gene in Aspergillus niger.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

The solubility and stability of recombinant proteins are increased by their fusion to NusA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Bacteria co-transformed with recombinant proteins and chaperones cloned in independent plasmids are suitable for expression tuning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Effects of gene dosage, promoters, and substrates on unfolded protein stress of recombinant Pichia pastoris

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Production of a biotinylated single-chain antibody fragment in the cytoplasm of Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Temperature effect on inclusion body formation and stress response in the periplasm of Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

The effects of drugs inhibiting protein secretion in the filamentous fungus Trichoderma reesei. Evidence for down-regulation of genes that encode secreted proteins in the stressed cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Refolding of substrates bound to small Hsps relies on a disaggregation reaction mediated most efficiently by ClpB/DnaK.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Role of molecular chaperones in inclusion body formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Genomic analysis of the unfolded protein response in Arabidopsis shows its connection to important cellular processes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Coexpression of BiP increased antithrombotic hirudin production in recombinant Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

DsbA and DsbC-catalyzed oxidative folding of proteins with complex disulfide bridge patterns in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Production of functional single-chain Fv antibodies in the cytoplasm of Escherichia coli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Overproduction of BiP negatively affects the secretion of Aspergillus niger glucose oxidase by the yeast Hansenula polymorpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Gene expression response to misfolded protein as a screen for soluble recombinant protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

The foldase CYPB is a component of the secretory pathway of Aspergillus niger and contains the endoplasmic reticulum retention signal HEEL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Effects of calnexin deletion in Saccharomyces cerevisiae on the secretion of glycosylated lysozymes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Production of correctly folded Fab antibody fragment in the cytoplasm of Escherichia coli trxB gor mutants via the coexpression of molecular chaperones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

A novel two-component regulatory system in Bacillus subtilis for the survival of severe secretion stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Production of tissue plasminogen activator (t-PA) in Aspergillus niger

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Low-temperature increases the yield of biologically active herring antifreeze protein in Pichia pastoris

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Low external pH induces HOG1-dependent changes in the organization of the Saccharomyces cerevisiae cell wall.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Enhanced secretion of hydrophobic peptide fused lysozyme by the introduction of N-glycosylation signal and the disruption of calnexin gene in Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Specific aggregation of partially folded polypeptide chains: the molecular basis of inclusion body composition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Eukaryotic protein disulfide isomerase complements Escherichia coli dsbA mutants and increases the yield of a heterologous secreted protein with disulfide bonds.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Characterization of inclusion bodies in recombinant Escherichia coli producing high levels of porcine somatotropin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 September 2018

Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2322954

21 October 2018

Recombinant protein solubility—does more mean better?

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of the role of the gene bipA, encoding the major endoplasmic reticulum chaperone protein in the secretion of homologous and heterologous proteins in black Aspergilli

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of heat-shock response and inclusion body formation during temperature-induced production of basic fibroblast growth factor in high-cell-density cultures of recombinant Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The PrsA lipoprotein is essential for protein secretion in Bacillus subtilis and sets a limit for high-level secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A genetic link between the unfolded protein response and vesicle formation from the endoplasmic reticulum

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small heat shock proteins, ClpB and the DnaK system form a functional triade in reversing protein aggregation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple roles of the cellulase CBHI in enhancing production of fusion antibodies by the filamentous fungus Trichoderma reesei

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Facilitating the formation of disulfide bonds in the Escherichia coli periplasm via coexpression of yeast protein disulfide isomerase

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improving heterologous protein folding via molecular chaperone and foldase co-expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic interactions of Hrd3p and Der3p/Hrd1p with Sec61p suggest a retro-translocation complex mediating protein transport for ER degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of aggregation-prone recombinant proteins at low temperatures: a comparative study of the Escherichia coli cspA and tac promoter systems

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A defined level of protein disulfide isomerase expression is required for optimal secretion of thaumatin by Aspegillus awamori

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat-shock and stringent responses have overlapping protease activity in Escherichia coli. Implications for heterologous protein yield

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scale-up and optimization of the low-temperature inducible cspA promoter system

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The expression of recombinant genes from bacteriophage lambda strong promoters triggers the SOS response inEscherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of hyposmotic stress on exocytosis in isolated turbot, Scophthalmus maximus, hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein disulfide isomerase overexpression increases secretion of foreign proteins in Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretion of human proteins from yeast: stimulation by duplication of polyubiquitin and protein disulfide isomerase genes in Kluyveromyces lactis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A study of the yeast cell wall composition and structure in response to growth conditions and mode of cultivation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The CssRS two-component regulatory system controls a general secretion stress response in Bacillus subtilis

1 reference

https://pubmed.ncbi.nlm.nih.gov/18394160

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1475-2859-7-11

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

15 August 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

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