The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation (Q36098246)

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English	The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation (English)

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Europe PubMed Central

PMC publication ID

12 August 2017

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Meenhard Herlyn

11

object named as

Meenhard Herlyn

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Europe PubMed Central

PMC publication ID

12 August 2017

1

object named as

Takaomi Okawa

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Europe PubMed Central

12 August 2017

PMC publication ID

3

object named as

Jiri Kalabis

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Europe PubMed Central

12 August 2017

PMC publication ID

Carmen Z Michaylira

2

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Carmen Z Michaylira

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Europe PubMed Central

12 August 2017

PMC publication ID

author name string

Douglas B Stairs

4

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Europe PubMed Central

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12 August 2017

Hiroshi Nakagawa

5

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Europe PubMed Central

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12 August 2017

Claudia D Andl

6

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Europe PubMed Central

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12 August 2017

Cameron N Johnstone

7

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Europe PubMed Central

PMC publication ID

12 August 2017

Andres J Klein-Szanto

8

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Europe PubMed Central

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12 August 2017

Wafik S El-Deiry

9

1 reference

Europe PubMed Central

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12 August 2017

Edna Cukierman

10

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Europe PubMed Central

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12 August 2017

Anil K Rustgi

12

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12 August 2017

publication date

1 November 2007

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12 August 2017

Genes & Development

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12 August 2017

21

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Europe PubMed Central

PMC publication ID

12 August 2017

21

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

2788-2803

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Combinatorial activation of FAK and AKT by transforming growth factor-beta1 confers an anoikis-resistant phenotype to myofibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Cancer metastasis: building a framework

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

AKT induces senescence in primary esophageal epithelial cells but is permissive for differentiation as revealed in organotypic culture.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Cancer invasion and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Tensional homeostasis and the malignant phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Stroma-derived three-dimensional matrices are necessary and sufficient to promote desmoplastic differentiation of normal fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Matrix metalloproteinase inhibitors as anticancer therapeutics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Stromagenesis: the changing face of fibroblastic microenvironments during tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

The molecular mechanisms of oesophageal cancer

1 reference

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2 October 2017

Matrix metalloproteinases as therapeutic targets in cancer

1 reference

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2 October 2017

The tension mounts: mechanics meets morphogenesis and malignancy

1 reference

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2 October 2017

Expression of cell adhesion molecules in oesophageal carcinoma and its prognostic value

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

p53: traffic cop at the crossroads of DNA repair and recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Cancer genes and the pathways they control

1 reference

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2 October 2017

Ha-Ras(G12V) induces senescence in primary and immortalized human esophageal keratinocytes with p53 dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Molecular aspects of esophageal squamous cell carcinoma carcinogenesis

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Tumour invasion and matrix metalloproteinases.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

The tissue microenvironment as an epigenetic tumor modifier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Genetic Alterations in Esophageal Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Specific beta1 integrin site selectively regulates Akt/protein kinase B signaling via local activation of protein phosphatase 2A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Epidermal growth factor receptor mediates increased cell proliferation, migration, and aggregation in esophageal keratinocytes in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Telomerase activity in esophageal squamous cell carcinoma: down-regulation by chemotherapeutic agent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Tumors are unique organs defined by abnormal signaling and context

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Telomerase activity of cultured human pancreatic carcinoma cell lines correlates with their potential for migration and invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Matrix metalloproteinase 9 promoter activity is induced coincident with invasion during tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Akt/protein kinase B isoforms are differentially regulated by epidermal growth factor stimulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Genetic steps in the development of squamous cell carcinoma of the esophagus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Mitogen-activated protein kinase (MAPK) regulates the expression of progelatinase B (MMP-9) in breast epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Inhibition of the p38 mitogen-activated protein kinase by SB 203580 blocks PMA-induced Mr 92,000 type IV collagenase secretion and in vitro invasion

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2 October 2017

Metastatic potential correlates with enzymatic degradation of basement membrane collagen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 October 2017

Telomerase induces immortalization of human esophageal keratinocytes without p16INK4a inactivation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 July 2018

Requirement for specific proteases in cancer cell intravasation as revealed by a novel semiquantitative PCR-based assay.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 July 2018

Construction and characterization of a conditionally active version of the serine/threonine kinase Akt.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

2 July 2018

Matrix metalloproteinases expression correlates with survival in patients with esophageal squamous cell carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2045132

23 September 2018

Structures of p53 cancer mutants and mechanism of rescue by second-site suppressor mutations

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23 September 2018

The stroma as a crucial target in rat mammary gland carcinogenesis

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23 September 2018

Esophageal Cancer

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23 September 2018

Phosphatidylinositol 3-kinase activity in epidermal growth factor-stimulated matrix metalloproteinase-9 production and cell surface association.

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23 September 2018

Sustained activation of the mitogen-activated protein kinase pathway. A mechanism underlying receptor tyrosine kinase specificity for matrix metalloproteinase-9 induction and cell migration.

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23 September 2018

Telomerase activity and expression of the telomerase catalytic subunit, hTERT, in meningioma progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17974918

12 December 2020

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Matrix metalloproteinase 9 and the epidermal growth factor signal pathway in operable non-small cell lung cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17974918

12 December 2020

based on heuristic

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Gelatinolytic activity of matrix metalloproteinase-2 and -9 in oesophageal carcinoma; a study using in situ zymography

1 reference

https://pubmed.ncbi.nlm.nih.gov/17974918

12 December 2020

based on heuristic

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The discovery of anthranilic acid-based MMP inhibitors. Part 2: SAR of the 5-position and P1(1) groups

1 reference

https://pubmed.ncbi.nlm.nih.gov/17974918

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased expression of MMP-2 and MMP-9 in esophageal squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17974918

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular biology of esophageal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17974918

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prognostic significance of epidermal growth factor receptor in esophageal squamous cell carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/17974918

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Invasion and metastasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17974918

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase activity in human bladder cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17974918

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Telomerase and telomere length in the development and progression of premalignant lesions to colorectal cancer

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https://pubmed.ncbi.nlm.nih.gov/17974918

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Clinical significance of telomerase activation and telomeric restriction fragment (TRF) in cervical cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17974918

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Role of ERK and JNK pathways in regulating cell motility and matrix metalloproteinase 9 production in growth factor-stimulated human epidermal keratinocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17974918

12 December 2020

based on heuristic

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Epidermal growth factor receptor and cyclin D1 are independently amplified and overexpressed in esophageal squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17974918

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1101/GAD.1544507

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

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