Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation (Q35663953)

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scientific article published on 28 February 2007

Language	Label	Description	Also known as
English	Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation	scientific article published on 28 February 2007

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

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Jesper M Mathiesen

object named as

Jesper Mosolff Mathiesen

2

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object named as

Trond Ulven

5

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author name string

Lena Uller

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Lisa Alenmyr

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Magnus Korsgren

4

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Thomas Högberg

6

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Gunnar Andersson

7

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Carl G A Persson

8

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Evi Kostenis

9

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

publication date

28 February 2007

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Respiratory Research

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

16

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Resolution of airway disease: removal of inflammatory cells through apoptosis, egression or both?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810525

27 July 2018

Update on the role of prostaglandins in allergic lung inflammation: separating friends from foes, harder than you might think

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810525

27 July 2018

5. IgE, mast cells, basophils, and eosinophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810525

27 July 2018

Effects of steroid treatment on lung CC chemokines, apoptosis and transepithelial cell clearance during development and resolution of allergic airway inflammation.

1 reference

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27 July 2018

9alpha,11beta-PGF2 and its stereoisomer PGF2alpha are novel agonists of the chemoattractant receptor, CRTH2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810525

27 July 2018

Prostaglandin D2 induces chemotaxis in eosinophils via its receptor CRTH2 and eosinophils may cause severe ocular inflammation in patients with allergic conjunctivitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810525

27 July 2018

Activation of the prostaglandin D2 receptor DP2/CRTH2 increases allergic inflammation in mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810525

27 July 2018

Airway wall remodelling: the influence of corticosteroids

1 reference

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27 July 2018

Mast cells and basophils: friends as well as foes in bronchial asthma?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810525

27 July 2018

Structural determinants of arylacetic acid nonsteroidal anti-inflammatory drugs necessary for binding and activation of the prostaglandin D2 receptor CRTH2.

1 reference

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27 July 2018

Pharmacology and signaling of prostaglandin receptors: multiple roles in inflammation and immune modulation

1 reference

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27 July 2018

T-cell trafficking in asthma: lipid mediators grease the way.

1 reference

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27 July 2018

Thromboxane A2 inhibition: therapeutic potential in bronchial asthma

1 reference

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27 July 2018

11-Dehydro-thromboxane B2, a stable thromboxane metabolite, is a full agonist of chemoattractant receptor-homologous molecule expressed on TH2 cells (CRTH2) in human eosinophils and basophils

1 reference

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27 July 2018

Prostaglandin D2 reinforces Th2 type inflammatory responses of airways to low-dose antigen through bronchial expression of macrophage-derived chemokine

1 reference

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27 July 2018

An orally bioavailable small molecule antagonist of CRTH2, ramatroban (BAY u3405), inhibits prostaglandin D2-induced eosinophil migration in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810525

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Scintillation proximity assay of inositol phosphates in cell extracts: high-throughput measurement of G-protein-coupled receptor activation

1 reference

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27 July 2018

Asthma -- a need for a rethink?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810525

27 July 2018

Selective modulation of chemokinesis, degranulation, and apoptosis in eosinophils through the PGD2 receptors CRTH2 and DP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810525

27 July 2018

Prostaglandin D2 selectively induces chemotaxis in T helper type 2 cells, eosinophils, and basophils via seven-transmembrane receptor CRTH2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810525

27 July 2018

Allergic lung responses are increased in prostaglandin H synthase-deficient mice.

1 reference

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27 July 2018

The effect of ramatroban (BAY u 3405), a thromboxane A2 receptor antagonist, on nasal cavity volume and minimum cross-sectional area and nasal mucosal hemodynamics after nasal mucosal allergen challenge in patients with perennial allergic rhinitis

1 reference

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27 July 2018

Stimulation with thromboxane A2 (TXA2) receptor agonist enhances ICAM-1, VCAM-1 or ELAM-1 expression by human vascular endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810525

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810525

27 July 2018

Differential antagonism of airway contractile responses to prostaglandin (PG)D2 and 9 alpha, 11 beta-PGF2 by atropine, SK&F 88046 and SQ 29,548 in the guinea pig.

1 reference

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27 July 2018

Molecular Cloning and Characterization of the Human Prostanoid DP Receptor

1 reference

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27 July 2018

Molecular cloning of the human eosinophil peroxidase. Evidence for the existence of a peroxidase multigene family

1 reference

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27 July 2018

The effects of an oral thromboxane TP receptor antagonist BAY u 3405, on prostaglandin D2- and histamine-induced bronchoconstriction in asthma, and relationship to plasma drug concentrations

1 reference

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27 July 2018

Prostaglandin D2 plays an essential role in chronic allergic inflammation of the skin via CRTH2 receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810525

25 September 2018

1 reference

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25 September 2018

On the mechanism of interaction of potent surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2

1 reference

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25 September 2018

Minor structural modifications convert the dual TP/CRTH2 antagonist ramatroban into a highly selective and potent CRTH2 antagonist

1 reference

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A highly conserved glycine within linker I and the extreme C terminus of G protein alpha subunits interact cooperatively in switching G protein-coupled receptor-to-effector specificity

1 reference

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25 September 2018

Effects of prostaglandin D2, 15-deoxy-Delta12,14-prostaglandin J2, and selective DP1 and DP2 receptor agonists on pulmonary infiltration of eosinophils in Brown Norway rats

1 reference

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25 September 2018

Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor

1 reference

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25 September 2018

A critical role for eosinophils in allergic airways remodeling

1 reference

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25 September 2018

Defining a link with asthma in mice congenitally deficient in eosinophils.

1 reference

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25 September 2018

Differential modulation of human basophil functions through prostaglandin D2 receptors DP and chemoattractant receptor-homologous molecule expressed on Th2 cells/DP2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810525

25 September 2018

Chemoattractant receptor-homologous molecule expressed on Th2 cells activation in vivo increases blood leukocyte counts and its blockade abrogates 13,14-dihydro-15-keto-prostaglandin D2-induced eosinophilia in rats

1 reference

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25 September 2018

Delta 12-prostaglandin J2, a plasma metabolite of prostaglandin D2, causes eosinophil mobilization from the bone marrow and primes eosinophils for chemotaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810525

25 September 2018

The role of chemical mediators in eosinophil infiltration in allergic rhinitis in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1810525

25 September 2018

Selective cyclooxygenase-1 and -2 inhibitors each increase allergic inflammation and airway hyperresponsiveness in mice

1 reference

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25 September 2018

Lung tissue eosinophils may be cleared through luminal entry rather than apoptosis: effects of steroid treatment

1 reference

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25 September 2018

Allergic eosinophil-rich inflammation develops in lungs and airways of B cell-deficient mice

1 reference

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25 September 2018

The effect of a thromboxane A2 receptor antagonist BAY-u-3405 on experimental allergic reactions

1 reference

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25 September 2018

Prostaglandin D2 generation after activation of rat and human mast cells with anti-IgE.

1 reference

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25 September 2018

Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor

1 reference

https://api.crossref.org/works/10.1186%2F1465-9921-8-16

21 January 2018

Cutting edge: chemoattractant receptor-homologous molecule expressed on Th2 cells plays a restricting role on IL-5 production and eosinophil recruitment

1 reference

https://pubmed.ncbi.nlm.nih.gov/17328802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prostaglandin D2 as a mediator of allergic asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17328802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of thromboxane A2 receptor antagonist (Bay u 3405) on nasal symptoms after antigen challenge in sensitized guinea pigs

1 reference

https://pubmed.ncbi.nlm.nih.gov/17328802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

BAY u3405, a thromboxane A2 antagonist, reduces bronchial hyperresponsiveness in asthmatics

1 reference

https://pubmed.ncbi.nlm.nih.gov/17328802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-5 secretion by allergen-stimulated CD4+ T cells in primary culture: Relationship to expression of allergic disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17328802

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1465-9921-8-16

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

ResearchGate publication ID

0 references

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