Anti-Ro52 autoantibodies from patients with Sjögren's syndrome inhibit the Ro52 E3 ligase activity by blocking the E3/E2 interface. (Q35378702)

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11 February 2020

title

Anti-Ro52 autoantibodies from patients with Sjögren's syndrome inhibit the Ro52 E3 ligase activity by blocking the E3/E2 interface (English)

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11 February 2020

1 reference

1 reference

Madhanagopal Anandapadamanaban

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11 February 2020

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11 February 2020

Marie Wahren-Herlenius

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11 February 2020

Alexander Espinosa

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11 February 2020

Janosch Hennig

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11 February 2020

Aurélie Ambrosi

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11 February 2020

Martina Sandberg Abelius

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11 February 2020

Yi Sheng

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11 February 2020

Filippa Nyberg

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11 February 2020

Maria Sunnerhagen

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11 February 2020

language of work or name

English

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publication date

23 August 2011

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Journal of Biological Chemistry

11 February 2020

published in

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11 February 2020

volume

286

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11 February 2020

issue

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11 February 2020

page(s)

36478-36491

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Structural and functional comparison of the RING domains of two p53 E3 ligases, Mdm2 and Pirh2.

11 February 2020

cites work

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Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23-Th17 pathway

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12 July 2018

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Interactions between the quality control ubiquitin ligase CHIP and ubiquitin conjugating enzymes

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The fellowship of the RING: the RING-B-box linker region interacts with the RING in TRIM21/Ro52, contains a native autoantigenic epitope in Sjögren syndrome, and is an integral and conserved region in TRIM proteins

12 July 2018

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Interferon-alpha induces up-regulation and nuclear translocation of the Ro52 autoantigen as detected by a panel of novel Ro52-specific monoclonal antibodies

12 July 2018

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E2-BRCA1 RING interactions dictate synthesis of mono- or specific polyubiquitin chain linkages

12 July 2018

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Cutting edge: autoantigen Ro52 is an interferon inducible E3 ligase that ubiquitinates IRF-8 and enhances cytokine expression in macrophages

12 July 2018

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Structural basis for PRYSPRY-mediated tripartite motif (TRIM) protein function

12 July 2018

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TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

12 July 2018

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Structure, interactions, and dynamics of the RING domain from human TRAF6

12 July 2018

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Regulation of p27 degradation and S-phase progression by Ro52 RING finger protein

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Structural organization and Zn2+-dependent subdomain interactions involving autoantigenic epitopes in the Ring-B-box-coiled-coil (RBCC) region of Ro52

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Structurally derived mutations define congenital heart block-related epitopes within the 200-239 amino acid stretch of the Ro52 protein

12 July 2018

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Crossref

https://api.crossref.org/works/10.1074%2FJBC.M111.241786

Combined chemical shift changes and amino acid specific chemical shift mapping of protein-protein interactions

21 January 2018

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12 December 2020

A serologic marker for fetal risk of congenital heart block

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Revised criteria for the classification of rheumatoid arthritis

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12 December 2020

Characterisation of a novel cysteine/histidine-rich metal binding domain from Xenopus nuclear factor XNF7

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Maternal HLA antigens and antibodies to SS-A/Ro and SS-B/La. Comparison with systemic lupus erythematosus and primary Sjögren's syndrome

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12 December 2020

Ro/SS-A and La/SS-B Antibody Level Variation in Patients with Sjögren's Syndrome and Systemic Lupus Erythematosus

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12 December 2020

Ubiquitin and the control of protein fate in the secretory and endocytic pathways

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Altered flexibility in the substrate-binding site of related native and engineered high-alkaline Bacillus subtilisins

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Ubiquitin transfer from the E2 perspective: why is UbcH5 so promiscuous?

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Identifiers

DOI

10.1074/JBC.M111.241786

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21862588%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

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11 February 2020

PubMed publication ID

21862588

1 reference

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