Protein kinase C and AKT/protein kinase B in CD4+ T-lymphocytes: new partners in TCR/CD28 signal integration (Q34666940)

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English	Protein kinase C and AKT/protein kinase B in CD4+ T-lymphocytes: new partners in TCR/CD28 signal integration	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

1 reference

Europe PubMed Central

Protein kinase C and AKT/protein kinase B in CD4+ T-lymphocytes: new partners in TCR/CD28 signal integration (English)

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

author name string

Birgit Bauer

1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Gottfried Baier

2

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Europe PubMed Central

PubMed publication ID

3 August 2017

language of work or name

1 reference

based on heuristic

inferred from title

publication date

1 June 2002

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Molecular Immunology

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Europe PubMed Central

PubMed publication ID

3 August 2017

38

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

15

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

1087-1099

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

Protein kinase Ctheta: a new essential superstar on the T-cell stage

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Helper T cell anergy: from biochemistry to cancer pathophysiology and therapeutics.

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Co-stimulation-dependent activation of a JNK-kinase in T lymphocytes

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Molecular cloning and characterization of PKC theta, a novel member of the protein kinase C (PKC) gene family expressed predominantly in hematopoietic cells

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Protein kinase C-theta isoenzyme selective stimulation of the transcription factor complex AP-1 in T lymphocytes

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Cell-cycle regulation in immunity, tolerance and autoimmunity

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Complex formation and cooperation of protein kinase C theta and Akt1/protein kinase B alpha in the NF-kappa B transactivation cascade in Jurkat T cells

1 reference

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T cell expressed PKCtheta demonstrates cell-type selective function

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Protein kinase C theta and epsilon promote T-cell survival by a rsk-dependent phosphorylation and inactivation of BAD.

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Antigen-induced translocation of PKC-theta to membrane rafts is required for T cell activation

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Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1

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Role of the protein kinase C lambda/iota isoform in nuclear factor-kappaB activation by interleukin-1beta or tumor necrosis factor-alpha: cell type specificities

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Phosphatidylinositol 3-Kinase Couples the Interleukin-2 Receptor to the Cell Cycle Regulator E2F

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

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Activation-induced cell death

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Cutting edge: distinct motifs within CD28 regulate T cell proliferation and induction of Bcl-XL.

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Targeting of p300 to the interleukin-2 promoter via CREB-Rel cross-talk during mitogen and oncogenic molecular signaling in activated T-cells

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Coordinate transactivation of the interleukin-2 CD28 response element by c-Rel and ATF-1/CREB2.

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AKT/PKB and other D3 phosphoinositide-regulated kinases: kinase activation by phosphoinositide-dependent phosphorylation

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Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

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Regulation of protein kinase C zeta by PI 3-kinase and PDK-1

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NF-kappa B activation induced by T cell receptor/CD28 costimulation is mediated by protein kinase C-theta

1 reference

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SHP-1 regulates Lck-induced phosphatidylinositol 3-kinase phosphorylation and activity

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Cellular survival: a play in three Akts

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Protein kinase C isozymes and the regulation of diverse cell responses

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Impaired Fas response and autoimmunity in Pten+/- mice

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Synergistic activation of NF-kappa B by functional cooperation between vav and PKCtheta in T lymphocytes

1 reference

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Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

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Protein kinase Czeta is a negative regulator of protein kinase B activity

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CREB is a regulatory target for the protein kinase Akt/PKB

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The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

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Costimulation: building an immunological synapse

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Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells.

1 reference

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Cbl-b, a RING-type E3 ubiquitin ligase, targets phosphatidylinositol 3-kinase for ubiquitination in T cells.

1 reference

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Vav is a regulator of cytoskeletal reorganization mediated by the T-cell receptor

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Protein kinase C-zeta mediates NF-kappa B activation in human immunodeficiency virus-infected monocytes.

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Analysis of the role of protein kinase C-alpha, -epsilon, and -zeta in T cell activation

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Protein kinase Ctheta, a selective upstream regulator of JNK/SAPK and IL-2 promoter activation in Jurkat T cells

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CD2 signalling induces phosphorylation of CREB in primary lymphocytes

1 reference

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Co-stimulation of human peripheral blood mononuclear cells with IL-2 and anti-CD3 monoclonal antibodies induces phosphorylation of CREB.

1 reference

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Critical requirement for the membrane-proximal cytosolic tyrosine residue for CD28-mediated costimulation in vivo

1 reference

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Vav synergizes with protein kinase C theta to mediate IL-4 gene expression in response to CD28 costimulation in T cells

1 reference

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ZAP-70 and SLP-76 regulate protein kinase C-theta and NF-kappa B activation in response to engagement of CD3 and CD28.

1 reference

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1 reference

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The role of lipid rafts in T cell antigen receptor (TCR) signalling

1 reference

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Regulation of activation-induced cell death of mature T-lymphocyte populations

1 reference

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1 reference

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1 reference

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1 reference

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Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines

1 reference

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Signal transduction by the TCR for antigen

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Induction of NF-kappaB by the Akt/PKB kinase

1 reference

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inferred from DOI database lookup

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1 reference

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Subcellular localization and translocation of protein kinase C isoforms zeta and epsilon in human peripheral blood lymphocytes

1 reference

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based on heuristic

inferred from DOI database lookup

The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes

1 reference

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1 reference

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inferred from DOI database lookup

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1 reference

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inferred from DOI database lookup

Direct control of the Forkhead transcription factor AFX by protein kinase B

1 reference

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inferred from DOI database lookup

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1 reference

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The T cell antigen receptor activates phosphatidylinositol 3-kinase-regulated serine kinases protein kinase B and ribosomal S6 kinase 1

1 reference

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1 reference

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7 January 2021

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inferred from DOI database lookup

Activation of IkappaB kinase beta by protein kinase C isoforms

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

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1 reference

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1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

1 reference

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7 January 2021

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1 reference

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daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans

1 reference

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7 January 2021

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Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta

1 reference

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7 January 2021

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Regulation of protein kinase Ctheta function during T cell activation by Lck-mediated tyrosine phosphorylation

1 reference

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7 January 2021

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Inhibition of protein kinase C alpha expression by antisense RNA in transfected Jurkat cells

1 reference

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7 January 2021

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Partners in transcription: NFAT and AP-1.

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7 January 2021

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1 reference

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Inhibition of insulin-induced activation of Akt by a kinase-deficient mutant of the epsilon isozyme of protein kinase C

1 reference

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Direct interaction between protein kinase C theta (PKC theta) and 14-3-3 tau in T cells: 14-3-3 overexpression results in inhibition of PKC theta translocation and function

1 reference

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Oncogenic transformation induced by membrane-targeted Akt2 and Akt3.

1 reference

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7 January 2021

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inferred from DOI database lookup

Selective modulation of protein kinase C-theta during T-cell activation

1 reference

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7 January 2021

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inferred from DOI database lookup

Binding of protein kinase C isoforms to actin in Aplysia

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Monitoring the duration of antigen-receptor occupancy by calcineurin/glycogen-synthase-kinase-3 control of NF-AT nuclear shuttling.

1 reference

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Determination of the specific substrate sequence motifs of protein kinase C isozymes

1 reference

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7 January 2021

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The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans

1 reference

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inferred from DOI database lookup

Phosphatidylinositol 3-kinase/Akt activity regulates c-FLIP expression in tumor cells

1 reference

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7 January 2021

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inferred from DOI database lookup

Ligation of the T cell co-stimulatory receptor CD28 activates the serine-threonine protein kinase protein kinase B.

1 reference

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Expression of Active Protein Kinase B in T Cells Perturbs Both T and B Cell Homeostasis and Promotes Inflammation

1 reference

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Akt phosphorylates and regulates the orphan nuclear receptor Nur77

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Tcl1 enhances Akt kinase activity and mediates its nuclear translocation

1 reference

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7 January 2021

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inferred from DOI database lookup

The Actin Cytoskeleton and Lymphocyte Activation

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7 January 2021

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Molecular analysis of the interactions between protein kinase C-epsilon and filamentous actin

1 reference

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inferred from DOI database lookup

Identification and localization of an actin-binding motif that is unique to the epsilon isoform of protein kinase C and participates in the regulation of synaptic function

1 reference

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7 January 2021

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Membrane raft association of CD47 is necessary for actin polymerization and protein kinase C theta translocation in its synergistic activation of T cells

1 reference

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7 January 2021

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Phosphatidylinositol 3-kinase links the interleukin-2 receptor to protein kinase B and p70 S6 kinase

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7 January 2021

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Differential downstream functions of protein kinase Ceta and -theta in EL4 mouse thymoma cells

1 reference

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7 January 2021

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inferred from DOI database lookup

Inhibition of T cell apoptosis by IFN-beta rapidly reverses nuclear translocation of protein kinase C-delta.

1 reference

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7 January 2021

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Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation

1 reference

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7 January 2021

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Protein kinase C-theta participates in the activation of cyclic AMP-responsive element-binding protein and its subsequent binding to the -180 site of the IL-2 promoter in normal human T lymphocytes

1 reference

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T cell death and memory

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Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Targeting Src homology 2 domain-containing tyrosine phosphatase (SHP-1) into lipid rafts inhibits CD3-induced T cell activation

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

T Cell-Specific Loss of Pten Leads to Defects in Central and Peripheral Tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

T cell antigen receptor dependent signalling in human lymphocytes: cholera toxin inhibits interleukin-2 receptor expression but not interleukin-2 synthesis by preventing activation of a protein kinase C isotype, PKC-alpha

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Defective insulin-induced GLUT4 translocation in skeletal muscle of high fat-fed rats is associated with alterations in both Akt/protein kinase B and atypical protein kinase C (zeta/lambda) activities

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein kinase C and calcineurin synergize to activate IkappaB kinase and NF-kappaB in T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The PI3K-PDK1 connection: more than just a road to PKB

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Protein kinase C-theta mediates a selective T cell survival signal via phosphorylation of BAD

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Synergistic action of protein kinase C θ and calcineurin is sufficient for Fas ligand expression and induction of a crmA-sensitive apoptosis pathway in Jurkat T cells

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The amplification of TCR signaling by dynamic membrane microdomains

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

T-cell activation and the dynamic world of rafts

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The tumor suppressor PTEN regulates T cell survival and antigen receptor signaling by acting as a phosphatidylinositol 3-phosphatase

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Phosphoinositide 3-kinases in T lymphocyte activation

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Calcineurin preferentially synergizes with PKC-theta to activate JNK and IL-2 promoter in T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

T-cell signal transduction and the role of protein kinase C

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Membrane compartmentation is required for efficient T cell activation.

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Blocking of c-FLIP(L)--independent cycloheximide-induced apoptosis or Fas-mediated apoptosis by the CC chemokine receptor 9/TECK interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Multiple signals required for cyclic AMP-responsive element binding protein (CREB) binding protein interaction induced by CD3/CD28 costimulation

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Roles of the SHP-1 tyrosine phosphatase in the negative regulation of cell signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of membrane-associated adaptors in T cell receptor signalling

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases

1 reference

https://api.crossref.org/works/10.1016%2FS0161-5890%2802%2900011-1

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S0161-5890(02)00011-1

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

3 August 2017

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