Suppression of leukemia development caused by PTEN loss (Q34533833)

2 August 2017

title

Suppression of leukemia development caused by PTEN loss (English)

1 reference

2 August 2017

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Marileila Varella-Garcia

object named as

Marileila Varella-Garcia

1 reference

2 August 2017

Wei Guo

1 reference

2 August 2017

Suzanne Schubbert

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2 August 2017

James Y Chen

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2 August 2017

Bahram Valamehr

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2 August 2017

Sherly Mosessian

1 reference

2 August 2017

Hubing Shi

1 reference

2 August 2017

Nhi H Dang

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2 August 2017

Consuelo Garcia

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2 August 2017

Mariana F Theodoro

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2 August 2017

Hong Wu

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2 August 2017

language of work or name

English

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publication date

6 January 2011

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Proceedings of the National Academy of Sciences of the United States of America

2 August 2017

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inferred from page(s)

published in

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2 August 2017

volume

108

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2 August 2017

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2 August 2017

page(s)

1409-1414

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Regulation of PTEN by CK2 and Notch1 in primary T-cell acute lymphoblastic leukemia: rationale for combined use of CK2- and gamma-secretase inhibitors

2 August 2017

cites work

1 reference

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Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes

7 July 2018

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High frequency of PTEN, PI3K, and AKT abnormalities in T-cell acute lymphoblastic leukemia

7 July 2018

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The impact of NOTCH1, FBW7 and PTEN mutations on prognosis and downstream signaling in pediatric T-cell acute lymphoblastic leukemia: a report from the Children's Oncology Group

7 July 2018

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Bidirectional transport of amino acids regulates mTOR and autophagy

7 July 2018

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Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia.

7 July 2018

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Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation

7 July 2018

1 reference

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Critical roles of the PI3K/Akt signaling pathway in T cell development

7 July 2018

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7 July 2018

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Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

7 July 2018

1 reference

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Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation.

7 July 2018

1 reference

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Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment

7 July 2018

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Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers

7 July 2018

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New therapeutic strategies for the treatment of acute lymphoblastic leukaemia

7 July 2018

1 reference

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Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia

7 July 2018

1 reference

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Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

7 July 2018

1 reference

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Essential role of PI3Kdelta and PI3Kgamma in thymocyte survival

7 July 2018

1 reference

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Perturbations of the AKT signaling pathway in human cancer

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029702

Notch promotes survival of pre-T cells at the beta-selection checkpoint by regulating cellular metabolism

7 July 2018

1 reference

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

7 July 2018

1 reference

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Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

7 July 2018

1 reference

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The loss of PTEN allows TCR alphabeta lineage thymocytes to bypass IL-7 and Pre-TCR-mediated signaling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029702

Enforcing order within a complex locus: current perspectives on the control of V(D)J recombination at the murine T-cell receptor alpha/delta locus

7 July 2018

1 reference

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Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029702

Take care of your chromosomes lest cancer take care of you.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029702

NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029702

Cre/loxP-mediated inactivation of the murine Pten tumor suppressor gene.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029702

Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification

7 July 2018

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Generalized lacZ expression with the ROSA26 Cre reporter strain

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029702

RAG-1-deficient mice have no mature B and T lymphocytes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029702

Distinct roles for PTEN in prevention of T cell lymphoma and autoimmunity in mice

7 July 2018

1 reference

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Regulation of the TCRalpha repertoire by the survival window of CD4(+)CD8(+) thymocytes.

21 January 2018

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IFNalpha activates dormant haematopoietic stem cells in vivo.

21 January 2018

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Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1006937108

AKT signaling in normal and malignant cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1006937108

mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1006937108

Cutting edge: T cell development requires the combined activities of the p110gamma and p110delta catalytic isoforms of phosphatidylinositol 3-kinase.

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.1006937108

VE-Cadherin-Cre-recombinase transgenic mouse: a tool for lineage analysis and gene deletion in endothelial cells.

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.1006937108

Developmental and molecular characterization of emerging beta- and gammadelta-selected pre-T cells in the adult mouse thymus

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029702

Acceleration of apoptosis in CD4+CD8+ thymocytes by rapamycin accompanied by increased CD4+CD25+ T cells in the periphery

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3029702

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

27 October 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1006937108

Immunophenotyping of acute leukemia by flow cytometric analysis. Use of CD45 and right-angle light scatter to gate on leukemic blasts in three-color analysis

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21212363

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The effect of rapamycin on T cell development in mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21212363

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1006937108

1 reference

2 August 2017

0 references

1 reference

2 August 2017

1 reference