The FEN1 E359K germline mutation disrupts the FEN1-WRN interaction and FEN1 GEN activity, causing aneuploidy-associated cancers. (Q34161115)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24608430%20AND%20SRC:MED&resulttype=core&format=json

10 March 2020

title

The FEN1 E359K germline mutation disrupts the FEN1-WRN interaction and FEN1 GEN activity, causing aneuploidy-associated cancers (English)

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10 March 2020

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10 March 2020

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10 March 2020

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10 March 2020

L Chung

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10 March 2020

D Onyango

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10 March 2020

Z Guo

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10 March 2020

P Jia

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10 March 2020

H Dai

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10 March 2020

M Zhou

1 reference

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10 March 2020

W Lin

1 reference

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10 March 2020

I Pang

1 reference

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10 March 2020

H Li

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10 March 2020

Y-C Yuan

1 reference

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10 March 2020

Q Huang

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10 March 2020

L Zheng

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10 March 2020

A Nicolas

1 reference

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10 March 2020

W Chai

1 reference

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10 March 2020

D Raz

1 reference

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10 March 2020

B Shen

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10 March 2020

language of work or name

English

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publication date

10 March 2014

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10 March 2020

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10 March 2020

volume

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10 March 2020

issue

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10 March 2020

page(s)

902-911

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DNA secondary structures: stability and function of G-quadruplex structures

10 March 2020

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Structural basis for DNA strand separation by the unconventional winged-helix domain of RecQ helicase WRN

5 July 2018

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5 July 2018

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5 July 2018

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Human flap endonuclease I is in complex with telomerase and is required for telomerase-mediated telomere maintenance

5 July 2018

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Flap endonuclease 1 contributes to telomere stability

5 July 2018

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Comprehensive mapping of the C-terminus of flap endonuclease-1 reveals distinct interaction sites for five proteins that represent different DNA replication and repair pathways

5 July 2018

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5 July 2018

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5 July 2018

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Disruption of the FEN-1/PCNA interaction results in DNA replication defects, pulmonary hypoplasia, pancytopenia, and newborn lethality in mice

5 July 2018

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5 July 2018

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Complex minisatellite rearrangements generated in the total or partial absence of Rad27/hFEN1 activity occur in a single generation and are Rad51 and Rad52 dependent.

5 July 2018

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The DNA-protein interaction modes of FEN-1 with gap substrates and their implication in preventing duplication mutations.

5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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Chromosomal breakage-fusion-bridge events cause genetic intratumor heterogeneity

5 July 2018

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5 July 2018

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Lagging Strand DNA Synthesis at the Eukaryotic Replication Fork Involves Binding and Stimulation of FEN-1 by Proliferating Cell Nuclear Antigen

5 July 2018

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How Shelterin Solves the Telomere End-Protection Problem

5 July 2018

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Concerted action of exonuclease and Gap-dependent endonuclease activities of FEN-1 contributes to the resolution of triplet repeat sequences (CTG)n- and (GAA)n-derived secondary structures formed during maturation of Okazaki fragments

21 January 2018

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FEN1 ensures telomere stability by facilitating replication fork re-initiation

21 January 2018

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Fen1 mutations result in autoimmunity, chronic inflammation and cancers

21 January 2018

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FEN1 contributes to telomere stability in ALT-positive tumor cells

21 January 2018

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Expansion and length-dependent fragility of CTG repeats in yeast

28 October 2018

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A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2014.19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24608430%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

10 March 2020

0 references

1 reference

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10 March 2020

PubMed publication ID

24608430

1 reference

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