Signal transmission, rather than reception, is the underlying neurochemical abnormality in schizophrenia. (Q34011793)

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English	Signal transmission, rather than reception, is the underlying neurochemical abnormality in schizophrenia.	scientific article

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10954386%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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Signal transmission, rather than reception, is the underlying neurochemical abnormality in schizophrenia (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10954386%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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1

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9 November 2019

author name string

B Dean

1

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30 July 2017

publication date

1 August 2000

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9 November 2019

Australian and New Zealand Journal of Psychiatry

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9 November 2019

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9 November 2019

4

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9 November 2019

560-569

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9 November 2019

Schizophrenia--a brain disease? A critical review of structural and functional cerebral abnormality in the disorder

1 reference

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21 January 2018

Biological studies in schizophrenia

1 reference

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Increased brain dopamine and reduced glutamic acid decarboxylase and choline acetyl transferase activity in schizophrenia and related psychoses

1 reference

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21 January 2018

Increased concentrations and lateral asymmetry of amygdala dopamine in schizophrenia

1 reference

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Determination of monoamine and monoamine metabolites in the human brain: post mortem studies in a group of suicides and in a control group

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21 January 2018

Multiple receptors for dopamine

1 reference

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21 January 2018

Molecular biology of dopamine receptors

1 reference

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Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

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Clozapine. A novel antipsychotic agent

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Dopamine receptor transcript expression in striatum and prefrontal and occipital cortex. Focal abnormalities in orbitofrontal cortex in schizophrenia

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21 January 2018

[3H]raclopride binding to brain tissue from subjects with schizophrenia: methodological aspects

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Elevation of D4 dopamine receptor mRNA in postmortem schizophrenic brain

1 reference

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21 January 2018

No difference in the expression of the D4 gene in post-mortem frontal cortex from controls and schizophrenics

1 reference

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21 January 2018

Selective loss of dopamine D3-type receptor mRNA expression in parietal and motor cortices of patients with chronic schizophrenia

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Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects

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Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from a novel positron emission tomography method

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The evolution of the serotonin-dopamine antagonist concept

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Neurotransmitter Receptors in Frontal Cortex of Schizophrenics

1 reference

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21 January 2018

Decreased serotonin S2 and increased dopamine D2 receptors in chronic schizophrenics

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21 January 2018

Alterations in the cortical serotonergic system in schizophrenia: A postmortem study

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21 January 2018

Decreased serotonin2A receptors in Brodmann's area 9 from schizophrenic subjects. A pathological or pharmacological phenomenon?

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21 January 2018

5-HT1A and 5-HT2A receptor mRNAs and binding site densities are differentially altered in schizophrenia

1 reference

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21 January 2018

Serotonin 5-HT2 receptors in schizophrenia: a PET study using [18F]setoperone in neuroleptic-naive patients and normal subjects.

1 reference

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21 January 2018

No serotonin 5-HT2A receptor density abnormality in the cortex of schizophrenic patients studied with PET.

1 reference

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21 January 2018

Selective abnormalities of prefrontal serotonergic receptors in schizophrenia. A postmortem study.

1 reference

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21 January 2018

Serotonin1A receptors are increased in postmortem prefrontal cortex in schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2FJ.1440-1614.2000.00747.X

21 January 2018

Serotonin uptake sites and serotonin receptors are altered in the limbic system of schizophrenics

1 reference

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21 January 2018

No change in the density of the serotonin1A receptor, the serotonin4 receptor or the serotonin transporter in the dorsolateral prefrontal cortex from subjects with schizophrenia.

1 reference

https://api.crossref.org/works/10.1080%2FJ.1440-1614.2000.00747.X

21 January 2018

Differential changes in serotonin 5-HT1A and 5-HT2 receptor binding in patients with chronic schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2FJ.1440-1614.2000.00747.X

21 January 2018

Changes in the serotonin transporter in the hippocampus of subjects with schizophrenia identified using [3H]paroxetine.

1 reference

https://api.crossref.org/works/10.1080%2FJ.1440-1614.2000.00747.X

21 January 2018

Alterations in phencyclidine and sigma binding sites in schizophrenic brains. Effects of disease process and neuroleptic medication

1 reference

https://api.crossref.org/works/10.1080%2FJ.1440-1614.2000.00747.X

21 January 2018

Increased density of glutamate/N-methyl-D-aspartate receptors in putamen from schizophrenic patients

1 reference

https://api.crossref.org/works/10.1080%2FJ.1440-1614.2000.00747.X

21 January 2018

NR2B-containing NMDA receptors are up-regulated in temporal cortex in schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2FJ.1440-1614.2000.00747.X

21 January 2018

Increased [3H]kainic acid binding in the prefrontal cortex in schizophrenia

1 reference

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21 January 2018

Frontal cortical and left temporal glutamatergic dysfunction in schizophrenia

1 reference

https://api.crossref.org/works/10.1080%2FJ.1440-1614.2000.00747.X

21 January 2018

Neurotransmitters, receptors and neuropeptides in post-mortem brains of chronic schizophrenic patients.

1 reference

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21 January 2018

Quantitative autoradiographic analysis of glutamate binding sites in the hippocampal formation in normal and schizophrenic brain post mortem

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21 January 2018

Alpha-[3H]amino-3-hydroxy-5-methylisoxazole-4-propionic acid binding to human cerebral cortical membranes: minimal changes in postmortem brains of chronic schizophrenics

1 reference

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21 January 2018

Distribution of kainate receptor subunit mRNAs in human hippocampus, neocortex and cerebellum, and bilateral reduction of hippocampal GluR6 and KA2 transcripts in schizophrenia

1 reference

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Immunoautoradiographic evidence for a loss of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate-preferring non-N-methyl-D-aspartate glutamate receptors within the medial temporal lobe in schizophrenia

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Measurement of Glutamate and Glutamine in the Medial Prefrontal Cortex of Never-Treated Schizophrenic Patients and Healthy Controls by Proton Magnetic Resonance Spectroscopy

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Regionally selective deficits in uptake sites for glutamate and gamma-aminobutyric acid in the basal ganglia in schizophrenia

1 reference

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21 January 2018

Deficits of [3H]D-aspartate binding to glutamate uptake sites in striatal and accumbens tissue in patients with schizophrenia

1 reference

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gamma-Aminobutyric acid (Gaba) and the dopamine hypothesis of schizophrenia

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Gamma-aminobutyric-acid deficiency in brain of schizophrenic patients

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Chronic GABA treatment downregulates the GABAA receptor alpha 2 and alpha 3 subunit mRNAS as well as polypeptide expression in primary cultured cerebral cortical neurons

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Up-regulation of GABAA receptor binding on neurons of the prefrontal cortex in schizophrenic subjects

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21 January 2018

Changes in serotonin2A and GABA(A) receptors in schizophrenia: studies on the human dorsolateral prefrontal cortex

1 reference

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21 January 2018

Differences in the subregional and cellular distribution of GABAA receptor binding in the hippocampal formation of schizophrenic brain

1 reference

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21 January 2018

Benzodiazepine receptors in the post-mortem brain of suicide victims and schizophrenic subjects

1 reference

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Reduced [3H]flunitrazepam binding in cingulate cortex and hippocampus of postmortem schizophrenic brains: is selective loss of glutamatergic neurons associated with major psychoses?

1 reference

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21 January 2018

GABAA receptor subunit gene expression in human prefrontal cortex: comparison of schizophrenics and controls

1 reference

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Altered ratios of alternatively spliced long and short gamma2 subunit mRNAs of the gamma-amino butyrate type A receptor in prefrontal cortex of schizophrenics

1 reference

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21 January 2018

Correlation between reduced in vivo benzodiazepine receptor binding and severity of psychotic symptoms in schizophrenia

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Cognitive functioning and GABAA/benzodiazepine receptor binding in schizophrenia: a 123I-iomazenil SPET study.

1 reference

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21 January 2018

Deficit and hemispheric asymmetry of GABA uptake sites in the hippocampus in schizophrenia

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Schizophrenia and the parvalbumin-containing class of cortical local circuit neurons

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Gene expression for glutamic acid decarboxylase is reduced without loss of neurons in prefrontal cortex of schizophrenics.

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Abnormal regulation of corticopetal cholinergic neurons and impaired information processing in neuropsychiatric disorders

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Olanzapine versus haloperidol in the treatment of schizophrenia and schizoaffective and schizophreniform disorders: results of an international collaborative trial

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Radioreceptor binding profile of the atypical antipsychotic olanzapine

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Possible changes in striatal and limbic cholinergic systems in schizophrenia

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Various enzymes involved with putative neurotransmitters. Regional distribution in the brain of deceased mentally normal, chronic schizophrenics or organic brain syndrome patients

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Choline acetyltransferase in schizophrenia

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Increased muscarinic cholinergic receptors in prefrontal cortices of medicated schizophrenics

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Muscarinic1 and 2 receptor mRNA in the human caudate-putamen: no change in m1 mRNA in schizophrenia.

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The structural era of endocytosis

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(3H]MK-801 binding sites in postmortem brain regions of schizophrenic patients

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Autoradiography with [3H]8-OH-DPAT reveals increases in 5-HT1A receptors in ventral prefrontal cortex in schizophrenia

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10.1080/J.1440-1614.2000.00747.X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10954386%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10954386%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

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