The IKK complex: an integrator of all signals that activate NF-kappaB? (Q33877083)

29 July 2017

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title

The IKK complex: an integrator of all signals that activate NF-kappaB? (English)

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29 July 2017

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A Israël

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29 July 2017

language of work or name

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1 April 2000

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29 July 2017

published in

Trends in Cell Biology

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29 July 2017

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29 July 2017

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29 July 2017

page(s)

129-133

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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

29 July 2017

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Identification and characterization of an IkappaB kinase

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IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

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7 January 2021

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

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A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

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IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

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IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

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7 January 2021

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

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7 January 2021

IkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complex

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Multiple signals converging on NF-kappaB.

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Bridging the gap: composition, regulation, and physiological function of the IkappaB kinase complex

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A ubiquitin ligase complex essential for the NF-kappaB, Wnt/Wingless, and Hedgehog signaling pathways

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7 January 2021

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

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7 January 2021

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

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7 January 2021

Severe liver degeneration in mice lacking the IkappaB kinase 2 gene

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7 January 2021

Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

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IKK1-deficient mice exhibit abnormal development of skin and skeleton

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Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinase

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Limb and skin abnormalities in mice lacking IKKalpha

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Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB.

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Role of Rel/NF-kappaB transcription factors during the outgrowth of the vertebrate limb.

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7 January 2021

Inhibition of NF-kappaB activity results in disruption of the apical ectodermal ridge and aberrant limb morphogenesis.

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7 January 2021

IKKgamma mediates the interaction of cellular IkappaB kinases with the tax transforming protein of human T cell leukemia virus type 1.

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7 January 2021

Identification of a cell protein (FIP-3) as a modulator of NF-kappaB activity and as a target of an adenovirus inhibitor of tumor necrosis factor alpha-induced apoptosis

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IKAP is a scaffold protein of the IkappaB kinase complex

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The kinetics of association and phosphorylation of IkappaB isoforms by IkappaB kinase 2 correlate with their cellular regulation in human endothelial cells

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7 January 2021

IKK-i, a novel lipopolysaccharide-inducible kinase that is related to IkappaB kinases

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IKKepsilon is part of a novel PMA-inducible IkappaB kinase complex

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7 January 2021

The kinase TAK1 can activate the NIK-I kappaB as well as the MAP kinase cascade in the IL-1 signalling pathway

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7 January 2021

Functional interactions of transforming growth factor beta-activated kinase 1 with IkappaB kinases to stimulate NF-kappaB activation

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7 January 2021

The proto-oncogene Cot kinase participates in CD3/CD28 induction of NF-kappaB acting through the NF-kappaB-inducing kinase and IkappaB kinases

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7 January 2021

Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinase

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7 January 2021

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

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NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

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7 January 2021

Activation of phosphatidylinositol 3-kinase in response to interleukin-1 leads to phosphorylation and activation of the NF-kappaB p65/RelA subunit

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7 January 2021

IKKgamma serves as a docking subunit of the IkappaB kinase (IKK) and mediates interaction of IKK with the human T-cell leukemia virus Tax protein

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7 January 2021

Role of Adapter Function in Oncoprotein-mediated Activation of NF-κB

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7 January 2021

NF-kappaB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase

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7 January 2021

NAK is an IkappaB kinase-activating kinase

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7 January 2021

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Identifiers

DOI

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29 July 2017

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