Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels (Q33782557)

28507138

29 July 2017

title

Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels (English)

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29 July 2017

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10 June 2020

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10 June 2020

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10 June 2020

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10 June 2020

William J Hadden

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10 June 2020

Jennifer L Young

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Meg L McFetridge

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10 June 2020

Du Yong Kim

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Hermes Taylor-Weiner

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10 June 2020

Jessica H Wen

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10 June 2020

Karen Bieback

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10 June 2020

Brendan F Kennedy

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Joachim P Spatz

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10 June 2020

language of work or name

English

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publication date

15 May 2017

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28507138

Proceedings of the National Academy of Sciences of the United States of America

29 July 2017

published in

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volume

114

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issue

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page(s)

5647-5652

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describes a project that uses

10 June 2020

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

MRTF potentiates TEAD-YAP transcriptional activity causing metastasis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

High content image analysis of focal adhesion-dependent mechanosensitive stem cell differentiation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Vascular smooth muscle cell durotaxis depends on extracellular matrix composition

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Context-dependent switch in chemo/mechanotransduction via multilevel crosstalk among cytoskeleton-regulated MRTF and TAZ and TGFβ-regulated Smad3

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Quantitative micro-elastography: imaging of tissue elasticity using compression optical coherence elastography.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

In vitro cancer cell-ECM interactions inform in vivo cancer treatment

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Conformal nanopatterning of extracellular matrix proteins onto topographically complex surfaces.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Interplay of matrix stiffness and protein tethering in stem cell differentiation.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Mesenchymal stem cell durotaxis depends on substrate stiffness gradient strength

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Fabrication of hydrogels with steep stiffness gradients for studying cell mechanical response

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Complex stiffness gradient substrates for studying mechanotactic cell migration.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

The alignment and fusion assembly of adipose-derived stem cells on mechanically patterned matrices

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Extracellular-matrix tethering regulates stem-cell fate

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

In situ mechanical analysis of myofibrillar perturbation and aging on soft, bilayered Drosophila myocardium

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Mechanical derivation of functional myotubes from adipose-derived stem cells.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Role of YAP/TAZ in mechanotransduction

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Stiffness gradients mimicking in vivo tissue variation regulate mesenchymal stem cell fate

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Substrate Stiffness and Cell Area Predict Cellular Traction Stresses in Single Cells and Cells in Contact

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Hydrogels with time-dependent material properties enhance cardiomyocyte differentiation in vitro

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Mechanical regulation of cell function with geometrically modulated elastomeric substrates.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Matrix strains induced by cells: Computing how far cells can feel.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

How deeply cells feel: methods for thin gels.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Yap is a novel regulator of C2C12 myogenesis

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

PEGDA hydrogels with patterned elasticity: Novel tools for the study of cell response to substrate rigidity

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Vascular smooth muscle cell durotaxis depends on substrate stiffness gradient strength

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Fibroblast adaptation and stiffness matching to soft elastic substrates

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Physical plasticity of the nucleus in stem cell differentiation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Nuclear actin regulates dynamic subcellular localization and activity of the SRF cofactor MAL.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Rational design of hydrogels for tissue engineering: impact of physical factors on cell behavior

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Matrix elasticity directs stem cell lineage specification

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Regulation of human neural precursor cells by laminin and integrins

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Tissue cells feel and respond to the stiffness of their substrate

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Lamin A/C expression is a marker of mouse and human embryonic stem cell differentiation.

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Tensional homeostasis and the malignant phenotype

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Substrate compliance versus ligand density in cell on gel responses

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Megakaryoblastic Leukemia-1/2, a Transcriptional Co-activator of Serum Response Factor, Is Required for Skeletal Myogenic Differentiation

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Actin dynamics control SRF activity by regulation of its coactivator MAL

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Neurite branching on deformable substrates

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Cell locomotion and focal adhesions are regulated by the mechanical properties of the substrate

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

In vitro tubulogenesis of endothelial cells by relaxation of the coupling extracellular matrix-cytoskeleton

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Substrate flexibility regulates growth and apoptosis of normal but not transformed cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Cell movement is guided by the rigidity of the substrate

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Transfection of constitutively active mitogen-activated protein/extracellular signal-regulated kinase kinase confers tumorigenic and metastatic potentials to NIH3T3 cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Surface Chemical Gradient Affects the Differentiation of Human Adipose-Derived Stem Cells via ERK1/2 Signaling Pathway.

4 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1618239114

The influence of substrate stiffness gradients on primary human dermal fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1618239114

Directed Movement of Vascular Smooth Muscle Cells on Gradient-Compliant Hydrogels†

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1618239114

High throughput kinetic analysis of photopolymer conversion using composition and exposure time gradients

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1618239114

Micro-composite substrates for the study of cell-matrix mechanical interactions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1618239114

Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1618239114

Mechanical regulation of a molecular clutch defines force transmission and transduction in response to matrix rigidity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1618239114

MicroRNA-21 preserves the fibrotic mechanical memory of mesenchymal stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1618239114

Quantitative comparison of spot detection methods in fluorescence microscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1618239114

Preparation of hydrogel substrates with tunable mechanical properties

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5465928

Screening of rat mesenchymal stem cell behaviour on polydimethylsiloxane stiffness gradients

30 October 2018

1 reference

12 December 2020

Assaying stem cell mechanobiology on microfabricated elastomeric substrates with geometrically modulated rigidity

1 reference

12 December 2020

Creating stiffness gradient polyvinyl alcohol hydrogel using a simple gradual freezing-thawing method to investigate stem cell differentiation behaviors

1 reference

12 December 2020

Cytosolic free calcium and the cytoskeleton in the control of leukocyte chemotaxis

1 reference

12 December 2020

Neutrophil chemotaxis in linear and complex gradients of interleukin-8 formed in a microfabricated device

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1618239114

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28507138%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

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10 June 2020

28507138

1 reference

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