Role of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis (Q33756825)

29 July 2017

title

Role of the lysophospholipid mediators lysophosphatidic acid and sphingosine 1-phosphate in lung fibrosis (English)

1 reference

29 July 2017

1 reference

Barry S Shea

1 reference

29 July 2017

Andrew M Tager

series ordinal

1 reference

29 July 2017

publication date

1 July 2012

1 reference

Proceedings of the American Thoracic Society

29 July 2017

published in

1 reference

29 July 2017

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29 July 2017

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29 July 2017

page(s)

102-110

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Integrin αvβ5-mediated TGF-β activation by airway smooth muscle cells in asthma

29 July 2017

cites work

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Synthetic analogs of FTY720 [2-amino-2-(2-[4-octylphenyl]ethyl)-1,3-propanediol] differentially regulate pulmonary vascular permeability in vivo and in vitro

21 June 2018

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Recent advances in molecular targets and treatment of idiopathic pulmonary fibrosis: focus on TGFbeta signaling and the myofibroblast

21 June 2018

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Subcellular origin of sphingosine 1-phosphate is essential for its toxic effect in lyase-deficient neurons

21 June 2018

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Hypoxia enhances sphingosine kinase 2 activity and provokes sphingosine-1-phosphate-mediated chemoresistance in A549 lung cancer cells.

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Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor-beta-stimulated collagen production by cardiac fibroblasts

21 June 2018

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Differential regulation of sphingosine kinases 1 and 2 in lung injury

21 June 2018

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Sphingosine 1-phosphate rescues canine LPS-induced acute lung injury and alters systemic inflammatory cytokine production in vivo

21 June 2018

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Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells

21 June 2018

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Role of the chemokine receptor CXCR2 in bleomycin-induced pulmonary inflammation and fibrosis

21 June 2018

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High density lipoprotein-associated sphingosine 1-phosphate promotes endothelial barrier function

21 June 2018

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21 June 2018

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21 June 2018

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Sphingosine 1-phosphate potentiates human lung fibroblast chemotaxis through the S1P2 receptor

21 June 2018

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Principles of bioactive lipid signalling: lessons from sphingolipids

21 June 2018

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Does current knowledge explain the pathogenesis of idiopathic pulmonary fibrosis? A perspective

21 June 2018

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21 June 2018

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Accelerated variant of idiopathic pulmonary fibrosis: clinical behavior and gene expression pattern

21 June 2018

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Pulmonary endothelial cell barrier enhancement by FTY720 does not require the S1P1 receptor

21 June 2018

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Essential role of MMP-12 in Fas-induced lung fibrosis

21 June 2018

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Lysophosphatidic acid promoting corneal epithelial wound healing by transactivation of epidermal growth factor receptor

21 June 2018

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Immunomodulator FTY720 induces myofibroblast differentiation via the lysophospholipid receptor S1P3 and Smad3 signaling

21 June 2018

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Combinatorial activation of FAK and AKT by transforming growth factor-beta1 confers an anoikis-resistant phenotype to myofibroblasts

21 June 2018

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Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix

21 June 2018

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Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.

21 June 2018

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Transforming growth factor beta: a central modulator of pulmonary and airway inflammation and fibrosis

21 June 2018

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Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development

21 June 2018

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Role of epithelial cells in idiopathic pulmonary fibrosis: from innocent targets to serial killers

21 June 2018

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Evolving concepts of apoptosis in idiopathic pulmonary fibrosis

21 June 2018

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Ligation of protease-activated receptor 1 enhances alpha(v)beta6 integrin-dependent TGF-beta activation and promotes acute lung injury.

21 June 2018

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The role of CCL12 in the recruitment of fibrocytes and lung fibrosis.

21 June 2018

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Pathogenetic pathways and novel pharmacotherapeutic targets in idiopathic pulmonary fibrosis.

21 June 2018

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Proteolytic activation of latent TGF-beta precedes caspase-3 activation and enhances apoptotic death of lung epithelial cells

21 June 2018

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Emerging medicinal roles for lysophospholipid signaling

21 June 2018

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21 June 2018

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21 June 2018

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Absence of proteinase-activated receptor-1 signaling affords protection from bleomycin-induced lung inflammation and fibrosis

21 June 2018

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21 June 2018

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Early growth response gene 1-mediated apoptosis is essential for transforming growth factor beta1-induced pulmonary fibrosis

21 June 2018

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Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis

21 June 2018

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The ins and outs of lysophosphatidic acid signaling.

21 June 2018

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Mechanisms of lysophosphatidic acid production

21 June 2018

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21 June 2018

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Lysophosphatidic acid production and action: validated targets in cancer?

21 June 2018

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21 June 2018

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TGF-beta signaling and the fibrotic response

21 June 2018

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Phosphorylation and action of the immunomodulator FTY720 inhibits vascular endothelial cell growth factor-induced vascular permeability.

21 June 2018

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Coagulation, fibrinolysis, and fibrin deposition in acute lung injury

21 June 2018

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Lysophosphatidic acid as a novel cell survival/apoptotic factor.

21 June 2018

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Coagulation cascade proteases and tissue fibrosis

21 June 2018

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21 June 2018

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Cytoskeletal regulation of pulmonary vascular permeability

21 June 2018

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Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement

21 June 2018

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Topical application of the phospholipid growth factor lysophosphatidic acid promotes wound healing in vivo

21 June 2018

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21 June 2018

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21 June 2018

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PAI-1, fibrosis, and the elusive provisional fibrin matrix

21 June 2018

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Role of RhoA and Rho kinase in lysophosphatidic acid-induced endothelial barrier dysfunction

21 June 2018

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Bleomycin-induced pulmonary fibrosis in fibrinogen-null mice.

21 June 2018

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Lysophosphatidic acid prevents apoptosis in fibroblasts via G(i)-protein-mediated activation of mitogen-activated protein kinase

21 June 2018

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A gonadotropin-releasing hormone-responsive phosphatase hydrolyses lysophosphatidic acid within the plasma membrane of ovarian cancer cells

21 June 2018

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A total fibrinogen deficiency is compatible with the development of pulmonary fibrosis in mice

21 June 2018

1 reference

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Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate

21 June 2018

1 reference

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21 June 2018

Cutaneous wound healing

1 reference

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Modulation of intestinal epithelial wound healing in vitro and in vivo by lysophosphatidic acid.

21 June 2018

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The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis

21 June 2018

1 reference

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Expression of the human integrin beta6 subunit in alveolar type II cells and bronchiolar epithelial cells reverses lung inflammation in beta6 knockout mice

21 June 2018

1 reference

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Adenovector-mediated gene transfer of active transforming growth factor-beta1 induces prolonged severe fibrosis in rat lung

21 June 2018

1 reference

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Latent transforming growth factor-beta: structural features and mechanisms of activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455616

Wound healing--aiming for perfect skin regeneration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455616

Bleomycin-induced pulmonary fibrosis in transgenic mice that either lack or overexpress the murine plasminogen activator inhibitor-1 gene

21 June 2018

1 reference

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Fibroblast chemotactic response elicited by native bronchoalveolar lavage fluid from patients with fibrosing alveolitis

21 June 2018

1 reference

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Disruption of epithelial cell-matrix interactions induces apoptosis

21 June 2018

1 reference

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Effect of antibody to transforming growth factor beta on bleomycin induced accumulation of lung collagen in mice

21 June 2018

1 reference

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Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

21 June 2018

1 reference

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An immunohistochemical study of architectural remodeling and connective tissue synthesis in pulmonary fibrosis

21 June 2018

1 reference

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Bleomycin-induced interstitial pulmonary disease in the nude, athymic mouse

21 June 2018

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Idiopathic Pulmonary Fibrosis

21 June 2018

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https://api.crossref.org/works/10.1513%2FPATS.201201-005AW

Prevention of bleomycin-induced lung fibrosis by aerosolization of heparin or urokinase in rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1513%2FPATS.201201-005AW

Inhibition of pulmonary fibrosis by the chemokine IP-10/CXCL10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1513%2FPATS.201201-005AW

The lysophosphatidic acid receptor LPA1 links pulmonary fibrosis to lung injury by mediating fibroblast recruitment and vascular leak

21 January 2018

1 reference

https://api.crossref.org/works/10.1513%2FPATS.201201-005AW

Prostaglandin F(2alpha) receptor signaling facilitates bleomycin-induced pulmonary fibrosis independently of transforming growth factor-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1513%2FPATS.201201-005AW

Restoration of beta1A integrins is required for lysophosphatidic acid-induced migration of beta1-null mouse fibroblastic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1513%2FPATS.201201-005AW

Lysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alpha(q).

21 January 2018

1 reference

https://api.crossref.org/works/10.1513%2FPATS.201201-005AW

TGF-beta 1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1513%2FPATS.201201-005AW

Protective effects of sphingosine 1-phosphate in murine endotoxin-induced inflammatory lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1513%2FPATS.201201-005AW

Sphingosine 1-phosphate reduces vascular leak in murine and canine models of acute lung injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1513%2FPATS.201201-005AW

Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1513%2FPATS.201201-005AW

Sphingosine 1-phosphate inhibits ischemia reperfusion injury following experimental lung transplantation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1513%2FPATS.201201-005AW

Sphingosine-1-phosphate and its analogue FTY720 diminish acute pulmonary injury in rats with acute necrotizing pancreatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1513%2FPATS.201201-005AW

Matrilysin shedding of syndecan-1 regulates chemokine mobilization and transepithelial efflux of neutrophils in acute lung injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1513%2FPATS.201201-005AW

Growth factor-like phospholipids generated after corneal injury

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5455616

Inhibition of myofibroblast apoptosis by transforming growth factor beta(1)

30 October 2018

1 reference

12 December 2020

Sphingosine 1-Phosphate Mediates Proliferation and Survival of Mesoangioblasts

1 reference

12 December 2020

The functional PDGFbeta receptor-S1P1 receptor signaling complex is involved in regulating migration of mouse embryonic fibroblasts in response to platelet derived growth factor

1 reference

12 December 2020

MMP expression and abnormal lung permeability are important determinants of outcome in IPF

1 reference

12 December 2020

Neutralization of the CXC chemokine, macrophage inflammatory protein-2, attenuates bleomycin-induced pulmonary fibrosis

1 reference

12 December 2020

Induction of Apoptosis and Pulmonary Fibrosis in Mice in Response to Ligation of Fas Antigen

1 reference

12 December 2020

P21Waf1/Cip1/Sdi1 and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosis

1 reference

12 December 2020

T cell independence of bleomycin-induced pulmonary fibrosis

1 reference

12 December 2020

Influence of early neutrophil depletion on MMPs/TIMP-1 balance in bleomycin-induced lung fibrosis

1 reference

12 December 2020

Expression of apoptotic and antiapoptotic markers in epithelial cells in idiopathic pulmonary fibrosis

1 reference

12 December 2020

Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice

1 reference

12 December 2020

10.1513/PATS.201201-005AW

Identifiers

DOI

1 reference

29 July 2017

1 reference

29 July 2017

1 reference