Antioxidant therapies for traumatic brain injury (Q33637858)

28 July 2017

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title

Antioxidant therapies for traumatic brain injury (English)

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28 July 2017

main subject

traumatic brain injury

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author name string

Edward D Hall

series ordinal

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28 July 2017

Radhika A Vaishnav

series ordinal

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28 July 2017

Ayman G Mustafa

series ordinal

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28 July 2017

publication date

1 January 2010

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28 July 2017

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28 July 2017

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28 July 2017

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28 July 2017

page(s)

51-61

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Mitochondrial protection after traumatic brain injury by scavenging lipid peroxyl radicals

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Dietary curcumin supplementation counteracts reduction in levels of molecules involved in energy homeostasis after brain trauma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Deferoxamine reduces intracerebral hematoma-induced iron accumulation and neuronal death in piglets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Neuroprotection by resveratrol against traumatic brain injury in rats

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Nitric oxide as a cellular antioxidant: a little goes a long way.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Dietary curcumin counteracts the outcome of traumatic brain injury on oxidative stress, synaptic plasticity, and cognition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Efficacy and safety of dexanabinol in severe traumatic brain injury: results of a phase III randomised, placebo-controlled, clinical trial

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Clinical trials in head injury

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Free radical pathways in CNS injury

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Calcium channel blockers for acute traumatic brain injury

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Double-blind, randomized, vehicle-controlled study of high-dose tirilazad mesylate in women with aneurysmal subarachnoid hemorrhage. Part II. A cooperative study in North America

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

A multicenter trial on the efficacy of using tirilazad mesylate in cases of head injury.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Expression of nitric oxide synthase in the cerebral microvasculature after traumatic brain injury in the rat.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Attenuation of acute and chronic damage following traumatic brain injury in copper, zinc-superoxide dismutase transgenic mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Reduction of the neurological deficit in mice with traumatic brain injury by nitric oxide synthase inhibitors.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Neuroprotective efficacy of microvascularly-localized versus brain-penetrating antioxidants.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Cerebroprotective effect of stable nitroxide radicals in closed head injury in the rat.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Transgenic mice and knockout mutants in the study of oxidative stress in brain injury

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Randomized, double-blind, vehicle-controlled trial of tirilazad mesylate in patients with aneurysmal subarachnoid hemorrhage: a cooperative study in Europe, Australia, and New Zealand

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Free radicals in CNS injury.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Therapeutic potential of the lazaroids (21-aminosteroids) in acute central nervous system trauma, ischemia and subarachnoid hemorrhage.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Glutamate release and free radical production following brain injury: effects of posttraumatic hypothermia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Immunosuppressant FK506 promotes neurite outgrowth in cultures of PC12 cells and sensory ganglia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Regional lipid peroxidation in rat brain in vitro: possible role of endogenous iron

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Beneficial effects of acute intravenous ibuprofen on neurologic recovery of head-injured mice: comparison of cyclooxygenase inhibition with inhibition of thromboxane A2 synthetase or 5-lipoxygenase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Effects of the 21-aminosteroid U74006F on experimental head injury in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Oxygen radicals in brain injury

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Superoxide production in experimental brain injury

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Hemoglobin-mediated oxidant damage to the central nervous system requires endogenous ascorbate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Oxygen radicals in CNS damage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Effects of a 21-aminosteroid (U-74006F) on cerebral metabolites and edema after severe experimental head trauma.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

U-78517F: a potent inhibitor of lipid peroxidation with activity in experimental brain injury and ischemia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

The double-edged role of nitric oxide in brain function and superoxide-mediated injury

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

The novel 21-aminosteroid U74006F attenuates cerebral edema and improves survival after brain injury in the rat.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Biochemistry and pharmacology of lipid antioxidants in acute brain and spinal cord injury

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Dextran-coupled deferoxamine improves outcome in a murine model of head injury

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Direct measurement of hydroxyl radicals, lipid peroxidation, and blood-brain barrier disruption following unilateral cortical impact head injury in the rat.

21 June 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

Reduction of tyrosine nitration after N(omega)-nitro-L-arginine-methylester treatment of mice with traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

Early treatment with a novel inhibitor of lipid peroxidation (LY341122) improves histopathological outcome after moderate fluid percussion brain injury in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

Role of nitric oxide in traumatic brain injury in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

Effects of L-NAME and 7-NI on NOS catalytic activity and behavioral outcome after traumatic brain injury in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

Traumatic neuroprotection with inhibitors of nitric oxide and ADP-ribosylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

Protective effect of melatonin in a model of traumatic brain injury in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

Brain hydroxyl radical generation in acute experimental head injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

Innate gender-based proclivity in response to cytotoxicity and programmed cell death pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

Prevention of mitochondrial dysfunction in post-traumatic mouse brain by superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

Neuroprotective effects of resveratrol against traumatic brain injury in immature rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

Protective effect of melatonin against head trauma-induced hippocampal damage and spatial memory deficits in immature rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

The protective effect of alpha lipoic acid against traumatic brain injury in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

Oxidative stress following traumatic brain injury in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

alpha-Phenyl-tert-N-butyl nitrone (PBN) improves functional and morphological outcome after cortical contusion injury in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

The Mechanism by which 4-hydroxy-2,2,6,6-tetramethylpiperidene-1-oxyl (tempol) diverts peroxynitrite decomposition from nitrating to nitrosating species

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

Neuroprotective effects of tempol, a catalytic scavenger of peroxynitrite-derived free radicals, in a mouse traumatic brain injury model

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

Deferoxamine improves spatial memory performance following experimental brain injury in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

Peroxynitrite-mediated oxidative damage to brain mitochondria: Protective effects of peroxynitrite scavengers

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

Carbonyl scavenger and antiatherogenic effects of hydrazine derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.NURT.2009.10.021

Hydralazine inhibits compression and acrolein-mediated injuries in ex vivo spinal cord

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Effect of melatonin on brain oxidative damage induced by traumatic brain injury in immature rats.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-kappaB and AP-1.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Inducible nitric oxide synthase expression after traumatic brain injury and neuroprotection with aminoguanidine treatment in rats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Antioxidant, OPC-14117, attenuates edema formation, and subsequent tissue damage following cortical contusion in rats.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Mechanism of brain protection by nitroxide radicals in experimental model of closed-head injury

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Structure activity relationships of peroxynitrite scavengers an approach to nitric oxide neurotoxicity.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818465

Effects of melatonin on lipid peroxidation induced by oxygen radicals

30 October 2018

1 reference

12 December 2020

The reaction of melatonin with peroxynitrite: formation of melatonin radical cation and absence of stable nitrated products

1 reference

12 December 2020

Traumatic injury to rat brain upregulates neuronal nitric oxide synthase expression and L-[3H]nitroarginine binding

1 reference

12 December 2020

Temporal profiles and cellular sources of three nitric oxide synthase isoforms in the brain after experimental contusion

1 reference

12 December 2020

Peroxynitrite scavengers for the acute treatment of traumatic brain injury

1 reference

12 December 2020

Melatonin as a free radical scavenger in experimental head trauma

1 reference

12 December 2020

4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl (Tempol) inhibits peroxynitrite-mediated phenol nitration

1 reference

12 December 2020

Hemoglobin. A biologic fenton reagent

1 reference

12 December 2020

PEG-SOD after head injury

1 reference

12 December 2020

Reduction of the neurological deficit in mice with traumatic brain injury by nitric oxide synthase inhibitors

1 reference

12 December 2020

Reaction of peroxynitrite with melatonin: A mechanistic study

1 reference

12 December 2020

10.1016/J.NURT.2009.10.021

Identifiers

DOI

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Dimensions Publication ID

28 July 2017

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28 July 2017

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