Epigenomic plasticity enables human pancreatic α to β cell reprogramming. (Q30536573)

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English	Epigenomic plasticity enables human pancreatic α to β cell reprogramming.	scientific article

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3582140

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15 August 2017

title

Epigenomic plasticity enables human pancreatic α to β cell reprogramming. (English)

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author name string

Nuria C Bramswig

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Logan J Everett

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15 August 2017

Jonathan Schug

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Craig Dorrell

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Chengyang Liu

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Yanping Luo

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Philip R Streeter

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Ali Naji

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Markus Grompe

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Klaus H Kaestner

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10

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publication date

22 February 2013

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15 August 2017

published in

Journal of Clinical Investigation

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15 August 2017

volume

123

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issue

3

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page(s)

1275-1284

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Derepression of Polycomb targets during pancreatic organogenesis allows insulin-producing beta-cells to adopt a neural gene activity program

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Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss

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A map of open chromatin in human pancreatic islets

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The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells

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In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

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Histone deacetylase inhibitors modify pancreatic cell fate determination and amplify endocrine progenitors

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Hepatocyte Nuclear Factor 3β is Involved in Pancreatic β-Cell-Specific Transcription of the pdx-1 Gene

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20 June 2018

Epigenetics as a unifying principle in the aetiology of complex traits and diseases

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Isolation of major pancreatic cell types and long-term culture-initiating cells using novel human surface markers

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Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny

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Identifiers

DOI

10.1172/JCI66514

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stated in

Europe PubMed Central

PMC publication ID

3582140

retrieved

15 August 2017

PMC publication ID

3582140

1 reference

stated in

Europe PubMed Central

PMC publication ID

3582140

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15 August 2017

PubMed publication ID

23434589

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stated in

Europe PubMed Central

PMC publication ID

3582140

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15 August 2017

 

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