Activation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with age (Q28740775)

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Mikiyo Nakata

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Shunsuke Chikuma

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Nakako Izumi

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Le Thi Huong

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Mikako Maruya

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Hitoshi Nagaoka

Creative Commons Attribution 4.0 International

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language of work or name

English

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publication date

2011

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e29141

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start time

28 December 2011

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April 2022 Public Data File from Crossref

copyrighted

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cites work

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Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming

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AID is required to initiate Nbs1/gamma-H2AX focus formation and mutations at sites of class switching

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Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

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Two subsets of memory T lymphocytes with distinct homing potentials and effector functions

17 March 2017

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Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

17 March 2017

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Generalized lacZ expression with the ROSA26 Cre reporter strain

17 March 2017

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

17 March 2017

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Visualizing spatiotemporal dynamics of multicellular cell-cycle progression

7 April 2017

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Activation-induced cytidine deaminase mediates central tolerance in B cells

7 April 2017

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Activation-induced cytidine deaminase (AID) is required for B-cell tolerance in humans

3 June 2018

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Activation of AID by human T-cell leukemia virus Tax oncoprotein and the possible role of its constitutive expression in ATL genesis

3 June 2018

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Memory B and memory plasma cells

3 June 2018

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Preferential localization of IgG memory B cells adjacent to contracted germinal centers.

3 June 2018

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APOBEC3G generates nonsense mutations in human T-cell leukemia virus type 1 proviral genomes in vivo

3 June 2018

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Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells

3 June 2018

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Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency.

3 June 2018

1 reference

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B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers

3 June 2018

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PD-1+ memory phenotype CD4+ T cells expressing C/EBPalpha underlie T cell immunodepression in senescence and leukemia

3 June 2018

1 reference

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Activation-induced cytidine deaminase expression and activity in the absence of germinal centers: insights into hyper-IgM syndrome

3 June 2018

1 reference

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Interleukin-10 production by Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose

3 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

Nine lives: plasticity among T helper cell subsets

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

AID expression levels determine the extent of cMyc oncogenic translocations and the incidence of B cell tumor development

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

Instructive role of the transcription factor E2A in early B lymphopoiesis and germinal center B cell development

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

Class switch recombination and somatic hypermutation in early mouse B cells are mediated by B cell and Toll-like receptors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

Role of AID in tumorigenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

Regulation of AID expression in the immune response

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

Development in motion: helper T cells at work

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

T-independent activation-induced cytidine deaminase expression, class-switch recombination, and antibody production by immature/transitional 1 B cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

Faithful activation of an extra-bright red fluorescent protein in "knock-in" Cre-reporter mice ideally suited for lineage tracing studies.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

Activation-induced cytidine deaminase (AID) is expressed in normal spermatogenesis but only infrequently in testicular germ cell tumours.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

Spontaneous and homeostatic proliferation of CD4 T cells are regulated by different mechanisms

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

Hepatitis C virus induces a mutator phenotype: enhanced mutations of immunoglobulin and protooncogenes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

Molecular mechanism of class switch recombination: linkage with somatic hypermutation

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

Altered T cell development in mice with a targeted mutation of the CD3-epsilon gene

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin mu chain gene

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3247255

Activation-induced deaminase (AID)-directed hypermutation in the immunoglobulin Smu region: implication of AID involvement in a common step of class switch recombination and somatic hypermutation

3 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029141

AID is required for germinal center-derived lymphomagenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029141

AID is required for c-myc/IgH chromosome translocations in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029141

Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029141

Constitutive expression of AID leads to tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029141

Tissue-specific sensitivity to AID expression in transgenic mouse models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029141

A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029141

T cell-independent somatic hypermutation in murine B cells with an immature phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029141

Visualizing Memory Phenotype Development afterin VitroStimulation of CD4+T Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029141

IgA production without mu or delta chain expression in developing B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029141

Preferential generation of follicular B helper T cells from Foxp3+ T cells in gut Peyer's patches

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029141

Critical roles of activation-induced cytidine deaminase in the homeostasis of gut flora

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029141

Locus-specific somatic hypermutation in germinal centre T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029141

Multiple layers of B cell memory with different effector functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029141

The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029141

Requirement for lymphoid tissue-inducer cells in isolated follicle formation and T cell-independent immunoglobulin A generation in the gut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029141

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0029141

Physiologic activation of T cells via the T cell receptor induces NF-kappa B

21 January 2018

1 reference

12 December 2020

Recent immune status determines the source of antigens that drive homeostatic T cell expansion

1 reference

12 December 2020

Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium

1 reference

12 December 2020

Cutting edge: TLR2 directly triggers Th1 effector functions

1 reference

12 December 2020