Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum (Q28649962)

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English	Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

25 June 2017

Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum (English)

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25 June 2017

Plasmodium falciparum

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calcium-dependent protein kinase 5

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11 September 2018

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Matthew Berriman

27

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Grennady Wirjanata

11

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10

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Iñigo Angulo-Barturen

18

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6

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Thomas D Otto

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Kiaran Kirk

26

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Vicky M Avery

23

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Susan A. Charman

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Susan A Charman

17

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Natalie J Spillman

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Natalie J Spillman

7

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Andrea Ruecker

24

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Michael Delves

25

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Matthew Berriman

27

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Matthew Berriman

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25 June 2017

29

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Jeremy Burrows

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25 June 2017

author name string

Akhil B Vaidya

1

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25 June 2017

Joanne M Morrisey

2

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25 June 2017

Zhongsheng Zhang

3

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25 June 2017

Sudipta Das

4

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25 June 2017

Thomas M Daly

5

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25 June 2017

Matthew Wyvratt

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Peter Siegl

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Boni F Sebayang

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Ric N Price

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25 June 2017

Arnab Chatterjee

14

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Advait Nagle

15

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Marcin Stasiak

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25 June 2017

Santiago Ferrer

19

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25 June 2017

María Belén Jiménez-Díaz

20

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25 June 2017

María Santos Martínez

21

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25 June 2017

Francisco Javier Gamo

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Sandhya Kortagere

28

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25 June 2017

Erkang Fan

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25 June 2017

Lawrence W Bergman

31

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25 June 2017

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publication date

25 November 2014

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25 June 2017

Nature Communications

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25 June 2017

5

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25 June 2017

5521

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Europe PubMed Central

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25 June 2017

copyright license

Creative Commons Attribution 4.0 International

25 November 2014

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April 2022 Public Data File from Crossref

copyright status

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describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4263321/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Na(+) regulation in the malaria parasite Plasmodium falciparum involves the cation ATPase PfATP4 and is a target of the spiroindolone antimalarials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

17 March 2017

Ion and nutrient uptake by malaria parasite-infected erythrocytes

1 reference

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17 March 2017

Spiroindolones, a potent compound class for the treatment of malaria

1 reference

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17 March 2017

Estimating the global clinical burden of Plasmodium falciparum malaria in 2007

1 reference

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17 March 2017

Artemisinin Resistance in Plasmodium falciparum Malaria

1 reference

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Improved murine model of malaria using Plasmodium falciparum competent strains and non-myelodepleted NOD-scid IL2Rgammanull mice engrafted with human erythrocytes

1 reference

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A murine model of falciparum-malaria by in vivo selection of competent strains in non-myelodepleted mice engrafted with human erythrocytes

1 reference

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Efficient site-specific integration in Plasmodium falciparum chromosomes mediated by mycobacteriophage Bxb1 integrase

1 reference

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Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique

1 reference

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7 April 2017

Transformation with human dihydrofolate reductase renders malaria parasites insensitive to WR99210 but does not affect the intrinsic activity of proguanil

1 reference

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7 April 2017

A plant-like kinase in Plasmodium falciparum regulates parasite egress from erythrocytes

1 reference

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9 May 2017

Animal models of efficacy to accelerate drug discovery in malaria

1 reference

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3 June 2018

Male and female Plasmodium falciparum mature gametocytes show different responses to antimalarial drugs

1 reference

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3 June 2018

Malaria parasites tolerate a broad range of ionic environments and do not require host cation remodelling

1 reference

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3 June 2018

Comparative ex vivo activity of novel endoperoxides in multidrug-resistant plasmodium falciparum and P. vivax

1 reference

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3 June 2018

Variation among Plasmodium falciparum strains in their reliance on mitochondrial electron transport chain function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

3 June 2018

The state of the art in anti-malarial drug discovery and development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4263321

3 June 2018

Development and host cell modifications of Plasmodium falciparum blood stages in four dimensions.

1 reference

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3 June 2018

Artemisinin resistance—the clock is ticking

1 reference

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3 June 2018

Sodium or potassium efflux ATPase a fungal, bryophyte, and protozoal ATPase

1 reference

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Iterative Correction of Reference Nucleotides (iCORN) using second generation sequencing technology

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Structure-based design of novel small-molecule inhibitors of Plasmodium falciparum

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Amplification-free Illumina sequencing-library preparation facilitates improved mapping and assembly of (G+C)-biased genomes

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Artemisinin-based combination treatment of falciparum malaria.

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Artemisinin-based combinations

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Chloroquine-resistant malaria

1 reference

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3 June 2018

Perturbation of the pump-leak balance for Na(+) and K(+) in malaria-infected erythrocytes.

1 reference

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Membrane transport in the malaria-infected erythrocyte

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Expression and functional characterization of a Plasmodium falciparum Ca2+-ATPase (PfATP4) belonging to a subclass unique to apicomplexan organisms

1 reference

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Variations in frequencies of drug resistance in Plasmodium falciparum

1 reference

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3 June 2018

Artemisinin resistance on the Thai-Cambodian border

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6521

21 January 2018

Analysis of a cation-transporting ATPase of Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6521

21 January 2018

Na+ extrusion imposes an acid load on the intraerythrocytic malaria parasite

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6521

21 January 2018

Identifiers

10.1038/NCOMMS6521

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Europe PubMed Central

PubMed publication ID

25 June 2017

2014NatCo...5.5521V

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Consolidated OpenCitations Corpus – April 2017

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PMC publication ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Europe PubMed Central

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25 June 2017

ResearchGate publication ID

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