Dual phosphorylations underlie modulation of unitary KCNQ K(+) channels by Src tyrosine kinase (Q28575228)

31 January 2017

title

Dual phosphorylations underlie modulation of unitary KCNQ K(+) channels by Src tyrosine kinase (English)

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regulation of cation transmembrane transport

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main subject

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Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1904062

negative regulation of cation transmembrane transport

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Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1904063

positive regulation of cation transmembrane transport

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Gene Ontology release 2020-05-02

Nikita Gamper

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Yang Li

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31 January 2017

Paul Langlais

series ordinal

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31 January 2017

Feng Liu

series ordinal

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31 January 2017

Mark S. Shapiro

series ordinal

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31 January 2017

language of work or name

English

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publication date

29 October 2004

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Journal of Biological Chemistry

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published in

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volume

279

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31 January 2017

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31 January 2017

page(s)

45399–45407

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Activation of protein tyrosine kinase PYK2 by the m1 muscarinic acetylcholine receptor

31 January 2017

cites work

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Association of Src tyrosine kinase with a human potassium channel mediated by SH3 domain

21 January 2018

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A mechanism for combinatorial regulation of electrical activity: Potassium channel subunits capable of functioning as Src homology 3-dependent adaptors

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Two adaptor proteins differentially modulate the phosphorylation and biophysics of Kv1.3 ion channel by SRC kinase

21 January 2018

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Potentiation of neuronal L calcium channels by IGF-1 requires phosphorylation of the alpha1 subunit on a specific tyrosine residue

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IGF-1 Modulates N and L Calcium Channels in a PI 3-Kinase-Dependent Manner

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Novel form of crosstalk between G protein and tyrosine kinase pathways

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KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel

21 January 2018

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KCNQ4, a novel potassium channel expressed in sensory outer hair cells, is mutated in dominant deafness

21 January 2018

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Antibodies and a cysteine-modifying reagent show correspondence of M current in neurons to KCNQ2 and KCNQ3 K+ channels

21 January 2018

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K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

21 January 2018

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Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

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Calmodulin mediates Ca2+-dependent modulation of M-type K+ channels

21 January 2018

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Recovery from muscarinic modulation of M current channels requires phosphatidylinositol 4,5-bisphosphate synthesis

21 January 2018

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Regulation of KCNQ2/KCNQ3 current by G protein cycling: the kinetics of receptor-mediated signaling by Gq.

21 January 2018

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PIP(2) activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents

21 January 2018

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AKAP150 signaling complex promotes suppression of the M-current by muscarinic agonists

21 January 2018

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The hunting of the Src

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The Src family tyrosine kinases are required for platelet-derived growth factor-mediated signal transduction in NIH 3T3 cells

21 January 2018

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Single-channel analysis of KCNQ K+ channels reveals the mechanism of augmentation by a cysteine-modifying reagent.

21 January 2018

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Differential tetraethylammonium sensitivity of KCNQ1-4 potassium channels

21 January 2018

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Protein tyrosine kinase structure and function

21 January 2018

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Tyr527 is phosphorylated in pp60c-src: implications for regulation

21 January 2018

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beta-arrestin1 interacts with the catalytic domain of the tyrosine kinase c-SRC. Role of beta-arrestin1-dependent targeting of c-SRC in receptor endocytosis

21 January 2018

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Effect of the KCNQ potassium channel opener retigabine on single KCNQ2/3 channels expressed in CHO cells

21 January 2018

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Mechanisms underlying modulation of neuronal KCNQ2/KCNQ3 potassium channels by extracellular protons

21 January 2018

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C-terminal interaction of KCNQ2 and KCNQ3 K+ channels

21 January 2018

1 reference

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A carboxy-terminal domain determines the subunit specificity of KCNQ K+ channel assembly

21 January 2018

1 reference

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Interdomain Interactions Underlying Activation of Cyclic Nucleotide-Gated Channels

21 January 2018

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Alterations in conserved Kir channel-PIP2 interactions underlie channelopathies

21 January 2018

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Searching for specificity in SH domains

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M408410200

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31 January 2017

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