Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway (Q28217024)

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scientific article (publication date: May 2002)

Language	Label	Description	Also known as
English	Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway	scientific article (publication date: May 2002)

Statements

scholarly article

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Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway (English)

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phosphorylation

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author name string

Sharon Amit

1

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Ada Hatzubai

2

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Yaara Birman

3

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Jens S Andersen

4

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Etti Ben-Shushan

5

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Matthias Mann

6

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Yinon Ben-Neriah

7

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Irit Alkalay

8

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language of work or name

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publication date

1 May 2002

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Genes & Development

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16

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9

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1066-76

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1 reference

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A newly synthesized selective casein kinase I inhibitor, N-(2-aminoethyl)-5-chloroisoquinoline-8-sulfonamide, and affinity purification of casein kinase I from bovine testis

1 reference

https://pubmed.ncbi.nlm.nih.gov/12000790

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1101/GAD.230302

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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