VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation (Q28272241)

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Language	Label	Description	Also known as
English	VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation	scientific article

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scholarly article

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VprBP targets Merlin to the Roc1-Cul4A-DDB1 E3 ligase complex for degradation (English)

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author name string

J Huang

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J Chen

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language of work or name

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publication date

3 July 2008

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27

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29

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4056-64

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Cyclic AMP-dependent protein kinase phosphorylates merlin at serine 518 independently of p21-activated kinase and promotes merlin-ezrin heterodimerization

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

Molecular architecture and assembly of the DDB1-CUL4A ubiquitin ligase machinery

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

HIV-1 Vpr-mediated G2 arrest involves the DDB1-CUL4AVPRBP E3 ubiquitin ligase

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

ERM-Merlin and EBP50 protein families in plasma membrane organization and function

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

Evidence for a cytoskeleton attachment domain at the N-terminus of the NF2 protein

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

Interdomain interaction of merlin isoforms and its influence on intermolecular binding to NHE-RF

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

Molecular insights into neurofibromatosis 2.

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligases

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

Stealing the spotlight: CUL4-DDB1 ubiquitin ligase docks WD40-repeat proteins to destroy

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

The biphenyl/polychlorinated biphenyl-degradation locus (bph) of Pseudomonas sp. LB400 encodes four additional metabolic enzymes

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

Merlin, the Product of the Nf2 Tumor Suppressor Gene, Is an Inhibitor of the p21-Activated Kinase, Pak1

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

Merlin facilitates ubiquitination and degradation of transactivation-responsive RNA-binding protein.

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac.

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

Merlin/NF-2 mediates contact inhibition of growth by suppressing recruitment of Rac to the plasma membrane

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

Regulation of the neurofibromatosis type 2 tumor suppressor protein, merlin, by adhesion and growth arrest stimuli

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling.

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

The HIV1 protein Vpr acts to promote G2 cell cycle arrest by engaging a DDB1 and Cullin4A-containing ubiquitin ligase complex using VprBP/DCAF1 as an adaptor

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

Merlin differentially associates with the microtubule and actin cytoskeleton

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

Cytoplasmic retention of HIV-1 regulatory protein Vpr by protein-protein interaction with a novel human cytoplasmic protein VprBP.

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https://api.crossref.org/works/10.1038%2FONC.2008.44

31 March 2020

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10.1038/ONC.2008.44

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