Exploiting the yeast Saccharomyces cerevisiae for the study of the organization and evolution of complex genomes

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

A new bacteriophage P1-derived vector for the propagation of large human DNA fragments

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Segments missing from the draft human genome sequence can be isolated by transformation-associated recombination cloning in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Specific cloning of human DNA as yeast artificial chromosomes by transformation-associated recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Direct isolation of human BRCA2 gene by transformation-associated recombination in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Generation of large insert yeast artificial chromosome libraries

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Chromosome length controls mitotic chromosome segregation in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

pYAC-4 Neo, a yeast artificial chromosome vector which codes for G418 resistance in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Amplification of large artificial chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Yeast artificial chromosome vectors for efficient clone manipulation and mapping

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

A new yeast artificial chromosome vector designed for gene transfer into mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Transgenic mice generated by pronuclear injection of a yeast artificial chromosome.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Construction of human chromosome 21-specific yeast artificial chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Construction and characterization of a yeast artificial chromosome library for Xpter-Xq27.3: a systematic determination of cocloning rate and X-chromosome representation

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Characterization of four human YAC libraries for clone size, chimerism and X chromosome sequence representation

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Detection and characterization of chimeric yeast artificial-chromosome clones

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Chimeric YACs were generated at unreduced rates in conditions that suppress coligation

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Reduced occurrence of chimeric YACs in recombination-deficient hosts

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Large human YACs constructed in a rad52 strain show a reduced rate of chimerism

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Isolation of chromosome 21-specific yeast artificial chromosomes from a total human genome library

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Construction and characterization of yeast artificial chromosome libraries from the mouse genome

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

A yeast artificial chromosome (YAC) library containing 10 haploid chicken genome equivalents

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Construction and characterization of a 10-genome equivalent yeast artificial chromosome library for the laboratory rat, Rattus norvegicus

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

A bovine YAC library containing four- to five-fold genome equivalents

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Construction of a YAC library from barley cultivar Franka and identification of YAC-derived markers linked to the Rh2 gene conferring resistance to scald (Rhynchosporium secalis).

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Physical mapping of the Myxococcus xanthus genome by random cloning in yeast artificial chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Use of yeast artificial chromosome clones for mapping and walking within human chromosome segment 18q21.3.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Sequence of Plasmodium falciparum chromosomes 2, 10, 11 and 14

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Sequence and analysis of chromosome 2 of Dictyostelium discoideum

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Current methods for YAC clone characterization

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Modification and transfer into an embryonal carcinoma cell line of a 360-kilobase human-derived yeast artificial chromosome

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Recovery and potential utility of YACs as circular YACs/BACs

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Directed mutagenesis of YAC-cloned DNA using a rapid, PCR-based screening protocol

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Identification of tumor suppressor candidate genes by physical and sequence mapping of the TSLC1 region of human chromosome 11q23.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Chromosomal region of the cystic fibrosis gene in yeast artificial chromosomes: a model for human genome mapping

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Meiotic recombination between yeast artificial chromosomes yields a single clone containing the entire BCL2 protooncogene

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Reconstruction of the 2.4 Mb human DMD-gene by homologous YAC recombination

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

YAC transgenics and the study of genetics and human disease

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Generation of transgenic rats with YACs and BACs: preparation procedures and integrity of microinjected DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Transfer of YACs up to 2.3 Mb intact into human cells with polyethylenimine

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Alterations of yeast artificial chromosome transgenic sequences in stretched embryonic stem-cell chromatin visualized by fluorescence in situ hybridization

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Genomic targeting with a positive-selection lox integration vector allows highly reproducible gene expression in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

A cre-lox recombination system for the targeted integration of circular yeast artificial chromosomes into embryonic stem cells

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Introduction and expression of the 400 kilobase amyloid precursor protein gene in transgenic mice [corrected]

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Construction of a panel of transgenic mice containing a contiguous 2-Mb set of YAC/P1 clones from human chromosome 21q22.2.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Effect of deletion of 5'HS3 or 5'HS2 of the human beta-globin locus control region on the developmental regulation of globin gene expression in beta-globin locus yeast artificial chromosome transgenic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Plasmid construction by homologous recombination in yeast.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Protein engineering by cDNA recombination in yeasts: shuffling of mammalian cytochrome P-450 functions

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

A new vector for recombination-based cloning of large DNA fragments from yeast artificial chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Minimum Length of Sequence Homology Required forin VivoCloning by Homologous Recombination in Yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Efficient manipulation of the human adenovirus genome as an infectious yeast artificial chromosome clone

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Recombination during transformation as a source of chimeric mammalian artificial chromosomes in yeast (YACs)

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Isolation of a circular derivative of yeast chromosome III: implications for the mechanism of mating type interconversion

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Isolation and characterization of yeast ring chromosome III by a method applicable to other circular DNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Eukaryotic DNA segments capable of autonomous replication in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

The ARS309 chromosomal replicator of Saccharomyces cerevisiae depends on an exceptional ARS consensus sequence.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

A genetic system for direct selection of gene-positive clones during recombinational cloning in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Defining the minimal length of sequence homology required for selective gene isolation by TAR cloning

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Highly selective isolation of human DNAs from rodent-human hybrid cells as circular yeast artificial chromosomes by transformation-associated recombination cloning

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Genetic variation at the O-antigen biosynthetic locus in Pseudomonas aeruginosa

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

A general cloning system to selectively isolate any eukaryotic or prokaryotic genomic region in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

DNA sequence elements required for transcription initiation of the Schizosaccharomyces pombe ADH gene in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Orientation-dependent and sequence-specific expansions of CTG/CAG trinucleotide repeats in Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Optimum conditions for selective isolation of genes from complex genomes by transformation-associated recombination cloning

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Structural instability of human tandemly repeated DNA sequences cloned in yeast artificial chromosome vectors

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Stabilisation of a yeast artificial chromosome containing plant DNA using a recombination-deficient host

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

A model system to assess the integrity of mammalian YACs during transformation and propagation in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Stabilization of yeast artificial chromosome clones in a rad54-3 recombination-deficient host strain

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Integrity of human YACs during propagation in recombination-deficient yeast strains

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Yeast kar1 mutants provide an effective method for YAC transfer to new hosts

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Functional copies of a human gene can be directly isolated by transformation-associated recombination cloning with a small 3' end target sequence.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Construction of human chromosome 16- and 5-specific circular YAC/BAC libraries by in vivo recombination in yeast (TAR cloning).

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Low-frequency chimeric yeast artificial chromosome libraries from flow-sorted human chromosomes 16 and 21.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Mapping of metastasis suppressor gene(s) for rat prostate cancer on the short arm of human chromosome 8 by irradiated microcell-mediated chromosome transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Isolation of a functional copy of the human BRCA1 gene by transformation-associated recombination in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Specific isolation of human rDNA genes by TAR cloning

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Direct cloning of human 10q25 neocentromere DNA using transformation-associated recombination (TAR) in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

The 10q25 neocentromere and its inactive progenitor have identical primary nucleotide sequence: further evidence for epigenetic modification

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Radial transformation-associated recombination cloning from the mouse genome: isolation of Tg.AC transgene with flanking DNAs

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Discovery of a novel, paternally expressed ubiquitin-specific processing protease gene through comparative analysis of an imprinted region of mouse chromosome 7 and human chromosome 19q13.4

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

The human telomerase gene: complete genomic sequence and analysis of tandem repeat polymorphisms in intronic regions

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

SKP2 associates with p130 and accelerates p130 ubiquitylation and degradation in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Large-insert BAC/YAC libraries for selective re-isolation of genomic regions by homologous recombination in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Sequence variability and candidate gene analysis in complex disease: association of mu opioid receptor gene variation with substance dependence

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Haplotypes vs single marker linkage disequilibrium tests: what do we gain?

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Cloning defined regions of the human genome by microdissection of banded chromosomes and enzymatic amplification

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Blocks of limited haplotype diversity revealed by high-resolution scanning of human chromosome 21.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Amplification and analysis of DNA sequences in single human sperm and diploid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Haplotype of multiple polymorphisms resolved by enzymatic amplification of single DNA molecules

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Repeat unit sequence variation in minisatellites: a novel source of DNA polymorphism for studying variation and mutation by single molecule analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Spermatid-specific expression of the novel X-linked gene product SPAN-X localized to the nucleus of human spermatozoa

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

A bacterial artificial chromosome library for sequencing the complete human genome

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Cloning of human centromeres by transformation-associated recombination in yeast and generation of functional human artificial chromosomes.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Human mini-chromosomes with minimal centromeres

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Formation of de novo centromeres and construction of first-generation human artificial microchromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Construction of YAC-based mammalian artificial chromosomes

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

CENP-B box is required for de novo centromere chromatin assembly on human alphoid DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Lethality of palindromic DNA and its use in selection of recombinant plasmids

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Occurrence of potential cruciform and H-DNA forming sequences in genomic DNA

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Tandem repeats 3' of the IGHA genes in the human immunoglobulin heavy chain gene cluster

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Non-clonability correlates with genomic instability: a case study of a unique DNA region

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Transformation-associated recombination between diverged and homologous DNA repeats is induced by strand breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Recombination between similar but not identical DNA sequences during yeast transformation occurs within short stretches of identity

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Homologous, homeologous, and illegitimate repair of double-strand breaks during transformation of a wild-type strain and a rad52 mutant strain of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Sequences flanking the centromere of human chromosome 10 are a complex patchwork of arm-specific sequences, stable duplications and unstable sequences with homologies to telomeric and other centromeric locations

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

The mosaic structure of human pericentromeric DNA: a strategy for characterizing complex regions of the human genome

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Segmental duplications: organization and impact within the current human genome project assembly

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

A novel strategy for analysis of gene homologues and segmental genome duplications

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Evolutionary parameters of the transcribed mammalian genome: an analysis of 2,820 orthologous rodent and human sequences

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

ASPM is a major determinant of cerebral cortical size

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Analysis of primate genomic variation reveals a repeat-driven expansion of the human genome

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021

Majority of divergence between closely related DNA samples is due to indels

1 reference

https://api.crossref.org/works/10.1016%2FS0168-6445%2803%2900070-6

7 January 2021