Antibiotics. Targeting DnaN for tuberculosis therapy using novel griselimycins (Q27700967)

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Deepak V Almeida

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Armin Bauer

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Evelyne Fontaine

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Sylvie Sordello

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Nestor Zaburannyi

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Jennifer Herrmann

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Silke C Wenzel

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Claudia König

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Nicole C Ammerman

0 references

María Belén Barrio

0 references

Kai Borchers

0 references

Florence Bordon-Pallier

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Mark Brönstrup

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Gilles Courtemanche

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Martin Gerlitz

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Michel Geslin

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Peter Hammann

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Dirk W Heinz

0 references

Holger Hoffmann

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Sylvie Klieber

0 references

Markus Kohlmann

0 references

Michael Kurz

0 references

Christine Lair

0 references

Hans Matter

0 references

Eric Nuermberger

0 references

Sandeep Tyagi

0 references

Laurent Fraisse

0 references

Jacques H Grosset

0 references

Sophie Lagrange

0 references

Rolf Müller

Towards a new tuberculosis drug: pyridomycin - nature's isoniazid

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language of work or name

English

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publication date

5 June 2015

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published in

Science

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volume

348

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issue

6239

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page(s)

1106-12

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cites work

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

Structural basis for recruitment of translesion DNA polymerase Pol IV/DinB to the -clamp

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

Structural and biochemical analysis of sliding clamp/ligand interactions suggest a competition between replicative and translesion DNA polymerases

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

Binding inhibitors of the bacterial sliding clamp by design

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

MRBAYES: Bayesian inference of phylogenetic trees

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

Protein production by auto-induction in high density shaking cultures

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

ExPASy: The proteomics server for in-depth protein knowledge and analysis

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

Data processing and analysis with the autoPROC toolbox

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

Scaling and assessment of data quality

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

Linking Crystallographic Model and Data Quality

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

Phasercrystallographic software

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

PHENIX: a comprehensive Python-based system for macromolecular structure solution

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

Crystal structure of DNA polymerase III β sliding clamp from Mycobacterium tuberculosis

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

Features and development of Coot

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

Towards automated crystallographic structure refinement with phenix.refine

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

Electrostatics of nanosystems: application to microtubules and the ribosome

22 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.AAA4690

Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2)

22 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Geneious Basic: an integrated and extendable desktop software platform for the organization and analysis of sequence data

22 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Mauve: multiple alignment of conserved genomic sequence with rearrangements

22 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Basic local alignment search tool

22 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Natural products as sources of new drugs over the 30 years from 1981 to 2010

22 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

LigPlot+: multiple ligand-protein interaction diagrams for drug discovery

22 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

A controlled trial of 6 months' chemotherapy in pulmonary tuberculosis. Final report: results during the 36 months after the end of chemotherapy and beyond. British Thoracic Society

22 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Aspects of the antituberculous activity of 27753-RP, a new semisynthetic derivative of griselimycine

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Transcription analysis of the dnaA gene and oriC region of the chromosome of Mycobacterium smegmatis and Mycobacterium bovis BCG, and its regulation by the DnaA protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Organization of the origins of replication of the chromosomes of Mycobacterium smegmatis, Mycobacterium leprae and Mycobacterium tuberculosis and isolation of a functional origin from M. smegmatis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

A bipartite polymerase-processivity factor interaction: only the internal beta binding site of the alpha subunit is required for processive replication by the DNA polymerase III holoenzyme.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Discovery of lead compounds targeting the bacterial sliding clamp using a fragment-based approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Quinolone-mediated bacterial death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

A bacterial toxin inhibits DNA replication elongation through a direct interaction with the β sliding clamp.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Conservation of eubacterial replicases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Identification of 4-amino-2-cyclohexylaminoquinazolines as metabolically stable melanin-concentrating hormone receptor 1 antagonists

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Structure-activity-relationship studies around the 2-amino group and pyridine core of antimalarial 3,5-diarylaminopyridines lead to a novel series of pyrazine analogues with oral in vivo activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Detection and classification of mutagens: a set of base-specific Salmonella tester strains

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Paradoxical effect of isoniazid on the activity of rifampin-pyrazinamide combination in a mouse model of tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Bioavailability of rifampin in experimental murine tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Treatment of Tuberculosis with Rifamycin-containing Regimens in Immune-deficient Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Determination of minimum inhibitory concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Analysis of genes involved in 6-deoxyhexose biosynthesis and transfer in Saccharopolyspora erythraea

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

How good are my data and what is the resolution?

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690

Coupling reagents and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.AAA4690