Crystal structure of the kinase domain of human vascular endothelial growth factor receptor 2: a key enzyme in angiogenesis (Q27618672)

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Language	Label	Description	Also known as
English	Crystal structure of the kinase domain of human vascular endothelial growth factor receptor 2: a key enzyme in angiogenesis	scientific article

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scholarly article

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Crystal structure of the kinase domain of human vascular endothelial growth factor receptor 2: a key enzyme in angiogenesis (English)

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crystal structure

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author name string

M A McTigue

1

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J A Wickersham

2

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C Pinko

3

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R E Showalter

4

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C V Parast

5

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A Tempczyk-Russell

6

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M R Gehring

7

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B Mroczkowski

8

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C C Kan

9

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J E Villafranca

10

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K Appelt

11

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language of work or name

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publication date

15 March 1999

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7

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3

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319-30

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Differentiation of endothelium.

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Positive and negative regulation of angiogenesis: from cell biology to the clinic

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Clinical research on antiangiogenic therapy

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Angiogenic factors in the development of diabetic iris neovascularization and retinopathy

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The biology of vascular endothelial growth factor

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Inhibition of vascular endothelial growth factor prevents retinal ischemia-associated iris neovascularization in a nonhuman primate

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Hyperplasia of lymphatic vessels in VEGF-C transgenic mice

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Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

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Deletion or substitution within the alpha platelet-derived growth factor receptor kinase insert domain: effects on functional coupling with intracellular signaling pathways

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Tyrosine mutations within the alpha platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transduction

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Interkinase domain of kit contains the binding site for phosphatidylinositol 3' kinase

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Domain movements in protein kinases

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10.1016/S0969-2126(99)80042-2

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24 November 2022

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