Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy. (Q27340721)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677466%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

title

Gain-of-function defects of astrocytic Kir4.1 channels in children with autism spectrum disorders and epilepsy (English)

1 reference

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Potassium inwardly-rectifying channel, subfamily J, member 10a

24 March 2020

main subject

autism spectrum disorder

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1 reference

GOA release 2020-03-11

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1 reference

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24 March 2020

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24 March 2020

1 reference

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24 March 2020

1 reference

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24 March 2020

Maria Stefania Brignone

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24 March 2020

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24 March 2020

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24 March 2020

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24 March 2020

Maria Cristina D'Adamo

1 reference

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24 March 2020

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24 March 2020

Filippo Maria Santorelli

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24 March 2020

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24 March 2020

Ilenio Servettini

1 reference

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24 March 2020

Giulia Valvo

1 reference

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24 March 2020

Angela Lanciotti

1 reference

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24 March 2020

Alessandro Grottesi

1 reference

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24 March 2020

Sara Baldini

1 reference

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24 March 2020

Fabio Franciolini

1 reference

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24 March 2020

language of work or name

English

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publication date

28 September 2016

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24 March 2020

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24 March 2020

volume

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24 March 2020

page(s)

34325

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Creative Commons Attribution 4.0 International

24 March 2020

start time

28 September 2016

1 reference

April 2022 Public Data File from Crossref

copyrighted

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cites work

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Episodic ataxia type-1 mutations in the hKv1.1 cytoplasmic pore region alter the gating properties of the channel

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Identification of a heteromeric interaction that influences the rectification, gating, and pH sensitivity of Kir4.1/Kir5.1 potassium channels

21 March 2017

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Mutations in the KCNA1 gene associated with episodic ataxia type-1 syndrome impair heteromeric voltage-gated K(+) channel function

21 March 2017

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21 March 2017

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Conditional knock-out of Kir4.1 leads to glial membrane depolarization, inhibition of potassium and glutamate uptake, and enhanced short-term synaptic potentiation

21 March 2017

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Analysis of astroglial K+ channel expression in the developing hippocampus reveals a predominant role of the Kir4.1 subunit

21 March 2017

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Downregulation of Kir4.1 inward rectifying potassium channel subunits by RNAi impairs potassium transfer and glutamate uptake by cultured cortical astrocytes

21 March 2017

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Potassium channel Kir4.1 macromolecular complex in retinal glial cells

21 March 2017

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21 March 2017

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The role of glial-specific Kir4.1 in normal and pathological states of the CNS.

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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29 September 2017

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Genetic Inactivation of Kcnj16 Identifies Kir5.1 as an Important Determinant of Neuronal PCO2/pH Sensitivity

29 September 2017

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Astrocytes and human cognition: modeling information integration and modulation of neuronal activity.

29 September 2017

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Cholesterol and ion channels

29 September 2017

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Linkage and linkage disequilibrium scan for autism loci in an extended pedigree from Finland

29 September 2017

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Seizures, sensorineural deafness, ataxia, mental retardation, and electrolyte imbalance (SeSAME syndrome) caused by mutations in KCNJ10.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5039625

Functional implications for Kir4.1 channels in glial biology: from K+ buffering to cell differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5039625

Distinct detergent-resistant membrane microdomains (lipid rafts) respectively harvest K(+) and water transport systems in brain astroglia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5039625

Functional expression of Kir4.1 channels in spinal cord astrocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5039625

New possible roles for aquaporin-4 in astrocytes: cell cytoskeleton and functional relationship with connexin43.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5039625

Mislocalization of Kir channels in malignant glia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5039625

pH gating of ROMK (K(ir)1.1) channels: control by an Arg-Lys-Arg triad disrupted in antenatal Bartter syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5039625

Subunit positional effects revealed by novel heteromeric inwardly rectifying K+ channels

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5039625

Intracellular pH transients of mammalian astrocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5039625

A conserved cytoplasmic region of ROMK modulates pH sensitivity, conductance, and gating.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5039625

Mechanisms of H+ and Na+ changes induced by glutamate, kainate, and D-aspartate in rat hippocampal astrocytes.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5039625

Autism with seizures and intellectual disability: possible causative role of gain-of-function of the inwardly-rectifying K+ channel Kir4.1.

2 June 2018

1 reference

Quantitative assessment of autism symptom-related traits in probands and parents: Broader Phenotype Autism Symptom Scale

21 January 2018

1 reference

pH dependence of the inwardly rectifying potassium channel, Kir5.1, and localization in renal tubular epithelia

21 January 2018

1 reference

A novel ATP-dependent inward rectifier potassium channel expressed predominantly in glial cells.

21 January 2018

1 reference

Astroglial potassium clearance contributes to short-term plasticity of synaptically evoked currents at the tripartite synapse

21 January 2018

1 reference

The potassium channel Kir4.1 associates with the dystrophin-glycoprotein complex via alpha-syntrophin in glia

21 January 2018

1 reference

Functional characterisation of missense variations in the Kir4.1 potassium channel (KCNJ10) associated with seizure susceptibility.

21 January 2018

1 reference

Contributions of the C-terminal domain to gating properties of inward rectifier potassium channels

21 January 2018

1 reference

Enhancement of glutamate uptake transport by CO(2)/bicarbonate in the leech giant glial cell

21 January 2018

1 reference

12 December 2020

Evidence that glial cells modulate extracellular pH transients induced by neuronal activity in the leech central nervous system

1 reference

12 December 2020

An inwardly rectifying K(+) channel, Kir4.1, expressed in astrocytes surrounds synapses and blood vessels in brain

1 reference

12 December 2020

Intracellular acidification and Ca2+ transients in cultured rat cerebellar astrocytes evoked by glutamate agonists and noradrenaline

1 reference

12 December 2020

Identifiers

DOI

10.1038/SREP34325

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677466%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

24 March 2020

1001539308

0 references

OpenCitations bibliographic resource ID

3306431

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3306431

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677466%20AND%20SRC:MED&resulttype=core&format=json

24 March 2020

PubMed publication ID

27677466

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27677466%20AND%20SRC:MED&resulttype=core&format=json