Cdc6 protein causes premature entry into S phase in a mammalian cell-free system (Q24533451)

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English	Cdc6 protein causes premature entry into S phase in a mammalian cell-free system	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

4 July 2017

Cdc6 protein causes premature entry into S phase in a mammalian cell-free system (English)

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Europe PubMed Central

PubMed publication ID

4 July 2017

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T Krude

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T

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Krude

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20 October 2023

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K Stoeber

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Stoeber

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4 July 2017

A D Mills

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Mills

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4 July 2017

Y Kubota

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Kubota

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4 July 2017

P Romanowski

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Romanowski

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4 July 2017

K Marheineke

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Marheineke

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4 July 2017

R A Laskey

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Laskey

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4 July 2017

G H Williams

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Williams

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4 July 2017

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publication date

1 December 1998

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4 July 2017

The EMBO Journal

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Europe PubMed Central

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4 July 2017

17

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4 July 2017

24

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Europe PubMed Central

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4 July 2017

7219-7229

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

24 March 2017

The Cdc4/34/53 pathway targets Cdc6p for proteolysis in budding yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

24 March 2017

A human protein related to yeast Cdc6p

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

24 March 2017

Different roles for cyclins D1 and E in regulation of the G1-to-S transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

24 March 2017

Human cyclin E, a nuclear protein essential for the G1-to-S phase transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

24 March 2017

Conserved initiator proteins in eukaryotes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

24 March 2017

Dual functions of CDC6: a yeast protein required for DNA replication also inhibits nuclear division

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

24 March 2017

Components and Dynamics of DNA Replication Complexes in S. cerevisiae: Redistribution of MCM Proteins and Cdc45p during S Phase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

24 March 2017

Loading of an Mcm protein onto DNA replication origins is regulated by Cdc6p and CDKs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

24 March 2017

Cdc6p-dependent loading of Mcm proteins onto pre-replicative chromatin in budding yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

24 March 2017

An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

24 March 2017

The Saccharomyces cerevisiae CDC6 gene is transcribed at late mitosis and encodes a ATP/GTPase controlling S phase initiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

24 March 2017

Cell cycle-regulated nuclear import and export of Cdc47, a protein essential for initiation of DNA replication in budding yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

24 March 2017

Initiation of DNA replication in eukaryotic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

24 March 2017

The Xenopus Cdc6 protein is essential for the initiation of a single round of DNA replication in cell-free extracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

24 March 2017

ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

24 March 2017

Over-production of proteins in Escherichia coli: mutant hosts that allow synthesis of some membrane proteins and globular proteins at high levels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

7 April 2017

Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

7 April 2017

Two steps in the assembly of complexes at yeast replication origins in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

7 April 2017

Chemical inhibitors of cyclin-dependent kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Regulated chromosomal DNA replication in the absence of a nucleus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Ectopic induction of Clb2 in early G1 phase is sufficient to block prereplicative complex formation in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

G1 cyclin-dependent kinases are sufficient to initiate DNA synthesis in quiescent human fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Cell cycle control of DNA replication.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Phosphorylation of MCM4 by cdc2 protein kinase inhibits the activity of the minichromosome maintenance complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

XMCM7, a novel member of the Xenopus MCM family, interacts with XMCM3 and colocalizes with it throughout replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Coordinating DNA replication with cell division: current status of the licensing concept

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Replication origins in eukaroytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Activation of S-phase-promoting CDKs in late G1 defines a "point of no return" after which Cdc6 synthesis cannot promote DNA replication in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

cdc18+ regulates initiation of DNA replication in Schizosaccharomyces pombe.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Chromotin binding, nuclear localization and phosphorylation of Xenopus cdc21 are cell-cycle dependent and associated with the control of initiation of DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Preventing re-replication of DNA in a single cell cycle: evidence for a replication licensing factor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Reversible effects of nuclear membrane permeabilization on DNA replication: evidence for a positive licensing factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Initiation of DNA replication in nuclei from quiescent cells requires permeabilization of the nuclear membrane

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

DNA polymerase alpha associated protein P1, a murine homolog of yeast MCM3, changes its intranuclear distribution during the DNA synthetic period.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

BM28, a human member of the MCM2-3-5 family, is displaced from chromatin during DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Dominant mutants identify new roles for p34cdc2 in mitosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

MCM3 complex required for cell cycle regulation of DNA replication in vertebrate cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Identification of the yeast MCM3-related protein as a component of Xenopus DNA replication licensing factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Cdc6 is an unstable protein whose de novo synthesis in G1 is important for the onset of S phase and for preventing a 'reductional' anaphase in the budding yeast Saccharomyces cerevisiae.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Nuclear DNA synthesis in vitro is mediated via stable replication forks assembled in a temporally specific fashion in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

A role for the nuclear envelope in controlling DNA replication within the cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Protein-DNA interactions at a yeast replication origin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Regulatory roles of the nuclear envelope

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Acceleration of the G1/S phase transition by expression of cyclins D1 and E with an inducible system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

27 September 2017

Putting It All Together: Building a Prereplicative Complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

30 May 2018

Interaction between the origin recognition complex and the replication licensing system in Xenopus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

30 May 2018

Determination of initiation of DNA replication before and after nuclear formation in Xenopus egg cell free extracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

30 May 2018

Purification of an MCM-containing complex as a component of the DNA replication licensing system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

30 May 2018

The nuclear membrane prevents replication of human G2 nuclei but not G1 nuclei in Xenopus egg extract

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

30 May 2018

Mechanisms restricting DNA replication to once per cell cycle: MCMS, pre-replicative complexes and kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

29 November 2018

Protein kinase inhibition in G2 causes mammalian Mcm proteins to reassociate with chromatin and restores ability to replicate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

29 November 2018

Cdc6p establishes and maintains a state of replication competence during G1 phase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

29 November 2018

Human replication proteins hCdc21, hCdc46 and P1Mcm3 bind chromatin uniformly before S-phase and are displaced locally during DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

29 November 2018

S-phase-promoting cyclin-dependent kinases prevent re-replication by inhibiting the transition of replication origins to a pre-replicative state

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

29 November 2018

Role for a Xenopus Orc2-related protein in controlling DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

29 November 2018

Regulation of progression through the G1 phase of the cell cycle by the rum1+ gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

29 November 2018

Inhibition of cyclin-dependent kinases by purine analogues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

29 November 2018

The fission yeast cdc18+ gene product couples S phase to START and mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

29 November 2018

Mammalian Cell Fusion : Studies on the Regulation of DNA Synthesis and Mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1171068

29 November 2018

The Xenopus origin recognition complex is essential for DNA replication and MCM binding to chromatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/9857179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p25rum1 orders S phase and mitosis by acting as an inhibitor of the p34cdc2 mitotic kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9857179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rum1 and Cdc18 link inhibition of cyclin-dependent kinase to the initiation of DNA replication in Schizosaccharomyces pombe

1 reference

https://pubmed.ncbi.nlm.nih.gov/9857179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nuclear envelope prevents reinitiation of replication by regulating the binding of MCM3 to chromatin in Xenopus egg extracts

1 reference

https://pubmed.ncbi.nlm.nih.gov/9857179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclin/Cdk-Dependent Initiation of DNA Replication in a Human Cell-Free System

1 reference

https://pubmed.ncbi.nlm.nih.gov/9857179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms restricting DNA replication to once per cell cycle: the role of Cdc6p and ORC

1 reference

https://pubmed.ncbi.nlm.nih.gov/9857179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ORC and Cdc6p interact and determine the frequency of initiation of DNA replication in the genome

1 reference

https://pubmed.ncbi.nlm.nih.gov/9857179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p65cdc18 plays a major role controlling the initiation of DNA replication in fission yeast

1 reference

https://pubmed.ncbi.nlm.nih.gov/9857179

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/EMBOJ/17.24.7219

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

release_bcqu2s7ypjhqldlsnytscjhdzy

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PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 July 2017

ResearchGate publication ID

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