Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor (Q24300354)

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Language	Label	Description	Also known as
English	Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor	scientific article

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scholarly article

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1 reference

Europe PubMed Central

Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor (English)

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F-box protein 5

1 reference

GOA release 2020-03-11

negative regulation of ubiquitin protein ligase activity

1 reference

GOA release 2020-03-11

object named as

David V Hansen

3

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Norman L. Lehman

object named as

Norman L Lehman

5

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Maxence V. Nachury

object named as

Maxence V Nachury

4

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author name string

Julie J Miller

1

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Matthew K Summers

2

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Alex Loktev

6

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Peter K Jackson

7

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language of work or name

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publication date

1 September 2006

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Genes & Development

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20

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17

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2410-20

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describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC1560415/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

19 March 2017

Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome

1 reference

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19 March 2017

The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex

1 reference

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19 March 2017

Prophase destruction of Emi1 by the SCF(betaTrCP/Slimb) ubiquitin ligase activates the anaphase promoting complex to allow progression beyond prometaphase

1 reference

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19 March 2017

E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

19 March 2017

Pseudosubstrate regulation of the SCF(beta-TrCP) ubiquitin ligase by hnRNP-U

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

19 March 2017

Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

19 March 2017

The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1

1 reference

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19 March 2017

TRIADs: a new class of proteins with a novel cysteine-rich signature

1 reference

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19 March 2017

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

1 reference

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19 March 2017

The WD40 propeller domain of Cdh1 functions as a destruction box receptor for APC/C substrates

1 reference

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19 March 2017

Doc1 mediates the activity of the anaphase-promoting complex by contributing to substrate recognition.

1 reference

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19 March 2017

Control of cyclin ubiquitination by CDK-regulated binding of Hct1 to the anaphase promoting complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

19 March 2017

CDC20 and CDH1: a family of substrate-specific activators of APC-dependent proteolysis.

1 reference

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19 March 2017

S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function

1 reference

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19 March 2017

Feedback control of mitosis in budding yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

19 March 2017

Cyclin is degraded by the ubiquitin pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

19 March 2017

How do so few control so many?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

19 March 2017

Timing and checkpoints in the regulation of mitotic progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

19 March 2017

Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

19 March 2017

Control of meiotic and mitotic progression by the F box protein beta-Trcp1 in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

19 March 2017

Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

19 March 2017

The anaphase inhibitor Pds1 binds to the APC/C-associated protein Cdc20 in a destruction box-dependent manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

19 March 2017

Emi1 is a mitotic regulator that interacts with Cdc20 and inhibits the anaphase promoting complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

19 March 2017

Identification of a cullin homology region in a subunit of the anaphase-promoting complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

19 March 2017

Anaphase-promoting complex/cyclosome-dependent proteolysis of human cyclin A starts at the beginning of mitosis and is not subject to the spindle assembly checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

19 March 2017

Yeast Hct1 is a regulator of Clb2 cyclin proteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

7 April 2017

Assembly of an APC-Cdh1-substrate complex is stimulated by engagement of a destruction box.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

27 September 2017

A role for the anaphase-promoting complex inhibitor Emi2/XErp1, a homolog of early mitotic inhibitor 1, in cytostatic factor arrest of Xenopus eggs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

27 September 2017

Xenopus polo-like kinase Plx1 regulates XErp1, a novel inhibitor of APC/C activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

27 September 2017

The anaphase-promoting complex: a key factor in the regulation of cell cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

27 September 2017

Stuck in division or passing through: what happens when cells cannot satisfy the spindle assembly checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

27 September 2017

Linking tumor suppression, DNA damage and the anaphase-promoting complex.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

27 September 2017

The anaphase-promoting complex: it's not just for mitosis any more.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

27 September 2017

Substrate recognition by the Cdc20 and Cdh1 components of the anaphase-promoting complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

27 September 2017

Hsl1p, a Swe1p inhibitor, is degraded via the anaphase-promoting complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

27 September 2017

Mutagenic analysis of the destruction signal of mitotic cyclins and structural characterization of ubiquitinated intermediates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

27 September 2017

Activation of the anaphase-promoting complex and degradation of cyclin B is not required for progression from Meiosis I to II in Xenopus oocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

30 May 2018

The APC subunit Doc1 promotes recognition of the substrate destruction box.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

29 November 2018

Cell cycle-regulated recognition of the destruction box of cyclin B by the APC/C in Xenopus egg extracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

29 November 2018

New B-type cyclin synthesis is required between meiosis I and II during Xenopus oocyte maturation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1560415

29 November 2018

Identifiers

10.1101/GAD.1454006

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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