Toxoplasma histone acetylation remodelers as novel drug targets (Q22305931)

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English	Toxoplasma histone acetylation remodelers as novel drug targets	scientific article

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19 February 2020

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Toxoplasma histone acetylation remodelers as novel drug targets (English)

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19 February 2020

histone acetylation

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based on heuristic

inferred from title

Victoria Jeffers

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Victoria Jeffers

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Victoria

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Jeffers

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19 February 2020

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Laura Vanagas

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19 February 2020

Silvina S Bogado

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19 February 2020

Maria C Dalmasso

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19 February 2020

William J Sullivan

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Sullivan

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19 February 2020

Sergio O Angel

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Sergio O

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Angel

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19 February 2020

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1 October 2012

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19 February 2020

Expert Review of Anti-infective Therapy

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19 February 2020

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19 February 2020

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19 February 2020

1189-1201

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19 February 2020

Regulation of chromatin by histone modifications

1 reference

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19 March 2017

Regulation of cellular metabolism by protein lysine acetylation

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19 March 2017

MYST family histone acetyltransferases in the protozoan parasite Toxoplasma gondii

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19 March 2017

Evolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteins

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19 March 2017

Acetylation of histones and transcription-related factors

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19 March 2017

Translating the Histone Code

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19 March 2017

Lysine acetylation targets protein complexes and co-regulates major cellular functions

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19 March 2017

Chromatin modifications and their function

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19 March 2017

The language of covalent histone modifications

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6 April 2017

Toxoplasma gondii lysine acetyltransferase GCN5-A functions in the cellular response to alkaline stress and expression of cyst genes

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Histone deacetylases play a major role in the transcriptional regulation of the Plasmodium falciparum life cycle

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Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase

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Histone variants: deviants?

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7 April 2017

Histone acetyltransferase complexes: one size doesn't fit all

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7 April 2017

Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum

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Telomeric heterochromatin propagation and histone acetylation control mutually exclusive expression of antigenic variation genes in malaria parasites

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A protein interaction network of the malaria parasite Plasmodium falciparum

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Histone variants and epigenetic inheritance

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27 September 2017

Lysine acetylation is widespread on proteins of diverse function and localization in the protozoan parasite Toxoplasma gondii

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HDAC inhibitors for the treatment of cutaneous T-cell lymphomas

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New antibacterials for the treatment of toxoplasmosis; a patent review

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27 September 2017

Small molecule inhibitors of histone acetyltransferases as epigenetic tools and drug candidates

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27 September 2017

Aberrant regulation of HDAC2 mediates proliferation of hepatocellular carcinoma cells by deregulating expression of G1/S cell cycle proteins

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27 September 2017

HDAC inhibitors in parasitic diseases

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27 September 2017

Mechanisms of Toxoplasma gondii persistence and latency

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Congenital parasitic infections: a review

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Promoting Illiteracy in Epigenetics: An Emerging Therapeutic Strategy

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Targeting HDACs: a promising therapy for Alzheimer's disease.

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Involvement of a Toxoplasma gondii chromatin remodeling complex ortholog in developmental regulation

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Vorinostat-induced apoptosis in mantle cell lymphoma is mediated by acetylation of proapoptotic BH3-only gene promoters

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Canonical and variant histones of protozoan parasites

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27 September 2017

Histone H4 Acetylation Differentially Modulates Arginine Methylation by an in Cis Mechanism

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The Apicomplexan AP2 family: Integral factors regulating Plasmodium development

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27 September 2017

Regions of intrinsic disorder help identify a novel nuclear localization signal in Toxoplasma gondii histone acetyltransferase TgGCN5-B

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27 September 2017

The program for processing newly synthesized histones H3.1 and H4

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27 September 2017

Activity of the histone deacetylase inhibitor FR235222 on Toxoplasma gondii: inhibition of stage conversion of the parasite cyst form and study of new derivative compounds

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A complex small RNA repertoire is generated by a plant/fungal-like machinery and effected by a metazoan-like Argonaute in the single-cell human parasite Toxoplasma gondii

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27 September 2017

A decade of epigenetic research in Toxoplasma gondii

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Toxoplasma gondii: epidemiology, feline clinical aspects, and prevention

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27 September 2017

MYST family lysine acetyltransferase facilitates ataxia telangiectasia mutated (ATM) kinase-mediated DNA damage response in Toxoplasma gondii

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27 September 2017

Chromatin modifications: implications in the regulation of gene expression in Toxoplasma gondii.

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27 September 2017

Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group

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Toxoplasma and schizophrenia

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27 September 2017

Protein methyltransferases as a target class for drug discovery

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27 September 2017

Proteome-wide prediction of acetylation substrates

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Toxoplasma H2A variants reveal novel insights into nucleosome composition and functions for this histone family

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Enhancing the apoptotic and therapeutic effects of HDAC inhibitors

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27 September 2017

Histone acetyltransferase inhibitor anacardic acid causes changes in global gene expression during in vitro Plasmodium falciparum development

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27 September 2017

The transcription of bradyzoite genes in Toxoplasma gondii is controlled by autonomous promoter elements.

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27 September 2017

Potent antimalarial activity of histone deacetylase inhibitor analogues.

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27 September 2017

Scriptaid and suberoylanilide hydroxamic acid are histone deacetylase inhibitors with potent anti-Toxoplasma gondii activity in vitro

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27 September 2017

Epigenomic modifications predict active promoters and gene structure in Toxoplasma gondii

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Prevention and treatment of congenital toxoplasmosis

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27 September 2017

Quinoline derivative MC1626, a putative GCN5 histone acetyltransferase (HAT) inhibitor, exhibits HAT-independent activity against Toxoplasma gondii

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27 September 2017

Cytotoxic effect of curcumin on malaria parasite Plasmodium falciparum: inhibition of histone acetylation and generation of reactive oxygen species

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27 September 2017

Histone deacetylase inhibitors: gathering pace

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27 September 2017

Histone mediated gene activation in Toxoplasma gondii

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27 September 2017

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27 September 2017

Histone-modifying complexes regulate gene expression pertinent to the differentiation of the protozoan parasite Toxoplasma gondii

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27 September 2017

RNAi-directed assembly of heterochromatin in fission yeast

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27 September 2017

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27 September 2017

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27 September 2017

Histone modification enzymes: novel targets for cancer drugs

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27 September 2017

Phylogenomics of the nucleosome

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27 September 2017

The diverse functions of histone acetyltransferase complexes.

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27 September 2017

Crosstalk between CARM1 methylation and CBP acetylation on histone H3.

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27 September 2017

Human testis/sperm-specific histone H2B (hTSH2B). Molecular cloning and characterization

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Histone modification: the 'next wave' in cancer therapeutics

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The major subacrosomal occupant of bull spermatozoa is a novel histone H2B variant associated with the forming acrosome during spermiogenesis.

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27 September 2017

Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure-activity relationships of apicidin. Part 2.

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27 September 2017

Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure-activity relationships of apicidin. Part 1.

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27 September 2017

Sir2 links chromatin silencing, metabolism, and aging

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27 September 2017

The development and biology of bradyzoites of Toxoplasma gondii

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27 September 2017

Toxoplasma gondii bradyzoites form spontaneously during sporozoite-initiated development

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27 September 2017

Detection of Toxoplasma gondii oocysts in drinking water.

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27 September 2017

Treatment of toxoplasmic encephalitis in patients with AIDS. A randomized trial comparing pyrimethamine plus clindamycin to pyrimethamine plus sulfadiazine. The California Collaborative Treatment Group

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Toxoplasmic encephalitis in AIDS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581047

27 September 2017

An insertional trap for conditional gene expression in Toxoplasma gondii: identification of TAF250 as an essential gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581047

30 May 2018

Computational screening of molecular targets in Plasmodium for novel non resistant anti-malarial drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581047

30 May 2018

Recent expansion of Toxoplasma through enhanced oral transmission

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

Foodborne outbreaks of human toxoplasmosis

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

Obsessive-compulsive disorder and acquired toxoplasmosis in two children

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

Is there any role of Toxoplasma gondii in the etiology of obsessive-compulsive disorder?

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

Brain cancer mortality rates increase with Toxoplasma gondii seroprevalence in France

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

The malaria parasite Plasmodium falciparum histones: organization, expression, and acetylation

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

Global histone analysis by mass spectrometry reveals a high content of acetylated lysine residues in the malaria parasite Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis.

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

PfADA2, a Plasmodium falciparum homologue of the transcriptional coactivator ADA2 and its in vivo association with the histone acetyltransferase PfGCN5.

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

Histone acetylase GCN5 enters the nucleus via importin-alpha in protozoan parasite Toxoplasma gondii

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

Heterochromatin silencing and locus repositioning linked to regulation of virulence genes in Plasmodium falciparum

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

Biochemical characterization of Plasmodium falciparum Sir2, a NAD+-dependent deacetylase

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

Plasmodium falciparum Sir2: an unusual sirtuin with dual histone deacetylase and ADP-ribosyltransferase activity

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

Drugs used in the treatment of schizophrenia and bipolar disorder inhibit the replication of Toxoplasma gondii

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

Schistosoma mansoni: developmental arrest of miracidia treated with histone deacetylase inhibitors

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

Histone deacetylase inhibitors induce apoptosis, histone hyperacetylation and up-regulation of gene transcription in Schistosoma mansoni.

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

Anti-malarial effect of histone deacetylation inhibitors and mammalian tumour cytodifferentiating agents

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

Nicotinamide inhibits Plasmodium falciparum Sir2 activity in vitro and parasite growth.

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

Stage-specific antileishmanial activity of an inhibitor of SIR2 histone deacetylase.

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

Plasmodium chabaudi: efficacy of artemisinin + curcumin combination treatment on a clone selected for artemisinin resistance in mice.

1 reference

https://api.crossref.org/works/10.1586%2FERI.12.100

21 January 2018

Histone H2AZ dimerizes with a novel variant H2B and is enriched at repetitive DNA in Trypanosoma brucei

1 reference

https://pubmed.ncbi.nlm.nih.gov/23199404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epigenetic mechanisms regulate stage differentiation in the minimized protozoan Giardia lamblia

1 reference

https://pubmed.ncbi.nlm.nih.gov/23199404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactivation of toxoplasma retinochoroiditis under atovaquone therapy in an immunocompetent patient

1 reference

https://pubmed.ncbi.nlm.nih.gov/23199404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toxoplasma gondii has two lineages of histones 2b (H2B) with different expression profiles

1 reference

https://pubmed.ncbi.nlm.nih.gov/23199404

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1586/ERI.12.100

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23199404%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23199404%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23199404%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

ResearchGate publication ID

0 references

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