SMA CARNI-VAL trial part I: double-blind, randomized, placebo-controlled trial of L-carnitine and valproic acid in spinal muscular atrophy (Q21562176)

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scientific article

SMA CARNI-VAL Trial Part I: Double-Blind, Randomized, Placebo-Controlled Trial of L-Carnitine and Valproic Acid in Spinal Muscular Atrophy

Language	Label	Description	Also known as
English	SMA CARNI-VAL trial part I: double-blind, randomized, placebo-controlled trial of L-carnitine and valproic acid in spinal muscular atrophy	scientific article	SMA CARNI-VAL Trial Part I: Double-Blind, Randomized, Placebo-Controlled Trial of L-Carnitine and Valproic Acid in Spinal Muscular Atrophy

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scholarly article

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SMA CARNI-VAL trial part I: double-blind, randomized, placebo-controlled trial of L-carnitine and valproic acid in spinal muscular atrophy (English)

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spinal muscular atrophy

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based on heuristic

inferred from title

placebo-controlled trial

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based on heuristic

inferred from title

muscular atrophy

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based on heuristic

inferred from title

Kristin J. Krosschell

object named as

Kristin J Krosschell

6

author given names

Kristin J

author last names

Krosschell

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PubMed publication ID

11 September 2022

Louise R Simard

object named as

Louise R Simard

4

author given names

Louise R

author last names

Simard

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PubMed publication ID

11 September 2022

Kathryn J Swoboda

1

object named as

Kathryn J Swoboda

author given names

Kathryn J

author last names

Swoboda

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PubMed publication ID

11 September 2022

author name string

Charles B Scott

2

author given names

Charles B

author last names

Scott

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PubMed publication ID

11 September 2022

Thomas O Crawford

3

author given names

Thomas O

author last names

Crawford

1 reference

PubMed publication ID

11 September 2022

Sandra P Reyna

5

author given names

Sandra P

author last names

Reyna

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PubMed publication ID

11 September 2022

Gyula Acsadi

7

author given names

Gyula

author last names

Acsadi

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PubMed publication ID

11 September 2022

Bakri Elsheik

8

author given names

Bakri

author last names

Elsheik

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PubMed publication ID

11 September 2022

Mary K Schroth

9

author given names

Mary K

author last names

Schroth

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PubMed publication ID

11 September 2022

Guy D'Anjou

10

author given names

Guy

author last names

D'Anjou

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PubMed publication ID

11 September 2022

Bernard LaSalle

11

author given names

Bernard

author last names

LaSalle

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PubMed publication ID

11 September 2022

Thomas W Prior

12

author given names

Thomas W

author last names

Prior

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PubMed publication ID

11 September 2022

Susan L Sorenson

13

author given names

Susan L

author last names

Sorenson

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PubMed publication ID

11 September 2022

Jo Anne Maczulski

14

author given names

Jo Anne

author last names

Maczulski

1 reference

PubMed publication ID

11 September 2022

Mark B Bromberg

15

author given names

Mark B

author last names

Bromberg

1 reference

PubMed publication ID

11 September 2022

Gary M Chan

16

author given names

Gary M

author last names

Chan

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PubMed publication ID

11 September 2022

John T Kissel

17

author given names

John T

author last names

Kissel

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PubMed publication ID

11 September 2022

language of work or name

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publication date

2010

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5

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8

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e12140

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copyright license

Creative Commons Attribution 4.0 International

19 August 2010

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April 2022 Public Data File from Crossref

copyright status

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Valproic acid increases the SMN2 protein level: a well-known drug as a potential therapy for spinal muscular atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

19 March 2017

The Hammersmith functional motor scale for children with spinal muscular atrophy: a scale to test ability and monitor progress in children with limited ambulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

19 March 2017

Phase II open label study of valproic acid in spinal muscular atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

19 March 2017

Multiple therapeutic effects of valproic acid in spinal muscular atrophy model mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

19 March 2017

A modified Hammersmith functional motor scale for use in multi-center research on spinal muscular atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

19 March 2017

Population frequencies of inherited neuromuscular diseases—A world survey

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

19 March 2017

Identification and characterization of a spinal muscular atrophy-determining gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

7 April 2017

A single nucleotide in the SMN gene regulates splicing and is responsible for spinal muscular atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

7 April 2017

Literature review: health-related quality of life measurement in pediatric oncology: hearing the voices of the children

1 reference

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12 September 2017

The survival of motor neurons protein determines the capacity for snRNP assembly: biochemical deficiency in spinal muscular atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

12 September 2017

Natural history of denervation in SMA: relation to age, SMN2 copy number, and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

12 September 2017

Review of the reliability and validity of myometry with children

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

12 September 2017

Quantitative analyses of SMN1 and SMN2 based on real-time lightCycler PCR: fast and highly reliable carrier testing and prediction of severity of spinal muscular atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

12 September 2017

A hungarian study on Werdnig-Hoffmann disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

12 September 2017

Incidence, prevalence, and gene frequency studies of chronic childhood spinal muscular atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

12 September 2017

Preclinical validation of a multiplex real-time assay to quantify SMN mRNA in patients with SMA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

27 September 2017

The role of histone acetylation in SMN gene expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

27 September 2017

Valproic acid increases SMN levels in spinal muscular atrophy patient cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

27 September 2017

Correlation between severity and SMN protein level in spinal muscular atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

27 September 2017

Spinal muscular atrophies: recent insights and impact on molecular diagnosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

27 September 2017

Mildly affected patients with spinal muscular atrophy are partially protected by an increased SMN2 copy number

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

30 May 2018

The genetic component in child mortality

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

30 May 2018

Molecular analysis of spinal muscular atrophy and modification of the phenotype by SMN2.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012140

21 January 2018

Homozygous SMN1 deletions in unaffected family members and modification of the phenotype by SMN2.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012140

21 January 2018

Endogenous alpha-synuclein is induced by valproic acid through histone deacetylase inhibition and participates in neuroprotection against glutamate-induced excitotoxicity.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012140

21 January 2018

Small-sample performance of the robust score test and its modifications in generalized estimating equations

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012140

21 January 2018

Epidemiology of neuromuscular disorders in the under-20 population in Bologna province, Italy

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012140

21 January 2018

Reliability of hand-held dynamometry in spinal muscular atrophy

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0012140

21 January 2018

Valproic acid treatment in six patients with spinal muscular atrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

29 November 2018

Benefit of valproic acid in suppressing disease progression of ALS model mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2924376

29 November 2018

Reliability of quantitative muscle testing in healthy children and in children with Duchenne muscular dystrophy using a hand-held dynamometer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20808854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Valproic Acid Promotes Neurite Outgrowth in PC12 Cells independent from Regulation of the Survival of Motoneuron Protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/20808854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo activation of SMN in spinal muscular atrophy carriers and patients treated with valproate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20808854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Valproate may improve strength and function in patients with type III/IV spinal muscle atrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20808854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Establishing a standardized therapeutic testing protocol for spinal muscular atrophy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20808854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reference values of maximum isometric muscle force obtained in 270 children aged 4–16 years by hand-held dynamometry

1 reference

https://pubmed.ncbi.nlm.nih.gov/20808854

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0012140

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2010PLoSO...512140S

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