Guanylate cyclase 1, soluble, alpha 1 (Q21495757)

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mammalian protein found in Mus musculus

• soluble guanylate cyclase large subunit
• alpha 1 sGC
• GCS-alpha-3
• guanylate cyclase 1, soluble, alpha 3
• GCS-alpha-1
• guanylate cyclase soluble subunit alpha-3
• guanylate cyclase soluble subunit alpha-1
• Gucy1a1
• Gucy1a3

edit

Language	Label	Description	Also known as
English	Guanylate cyclase 1, soluble, alpha 1	mammalian protein found in Mus musculus	soluble guanylate cyclase large subunit alpha 1 sGC GCS-alpha-3 guanylate cyclase 1, soluble, alpha 3 GCS-alpha-1 guanylate cyclase soluble subunit alpha-3 guanylate cyclase soluble subunit alpha-1 Gucy1a1 Gucy1a3

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q9ERL9

subclass of

protein

1 reference

stated in

UniProt

retrieved

19 January 2017

UniProt protein ID

Q9ERL9

part of

Nucleotide cyclase

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9ERL9

NO signalling/Golgi transport ligand-binding domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9ERL9

H-NOX domain superfamily

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9ERL9

Haem NO binding associated domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Adenylyl cyclase class-3/4/guanylyl cyclase family

1 reference

based on heuristic

inferred from protein domain or family

Adenylyl cyclase class-4/guanylyl cyclase, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

house mouse

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q9ERL9

encoded by

Gucy1a1

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q9ERL9

molecular function

nucleotide binding

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9ERL9

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

guanylate cyclase activity

determination method or standard

IBA

IEA

ISO

5 references

retrieved

21 June 2018

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERL9&geneProductId=UniProtKB:Q9ERL9

determination method or standard

ISO

retrieved

21 June 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q9ERL9

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERL9&geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

retrieved

21 June 2018

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERL9&geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

retrieved

21 June 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERL9&geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

retrieved

21 June 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERL9&geneProductId=UniProtKB:Q9ERL9

determination method or standard

IBA

lyase activity

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9ERL9

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

phosphorus-oxygen lyase activity

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

heme binding

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

adenylate cyclase activity

determination method or standard

IBA

ISO

2 references

retrieved

21 June 2018

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERL9&geneProductId=UniProtKB:Q9ERL9

determination method or standard

ISO

retrieved

21 June 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERL9&geneProductId=UniProtKB:Q9ERL9

determination method or standard

IBA

GTP binding

determination method or standard

IEA

ISO

2 references

retrieved

21 June 2018

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERL9&geneProductId=UniProtKB:Q9ERL9

determination method or standard

ISO

retrieved

21 June 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q9ERL9

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERL9&geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

ion binding

determination method or standard

ISO

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

ISO

protein heterodimerization activity

determination method or standard

ISO

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

ISO

cytidylate cyclase activity

determination method or standard

ISO

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

ISO

adenylate cyclase activity

determination method or standard

ISO

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

ISO

guanylate cyclase activity

determination method or standard

IEA

ISO

4 references

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

ISO

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9ERL9

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

retrieved

14 February 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

GTP binding

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9ERL9

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

cell component

cytoplasm

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9ERL9

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

plasma membrane

determination method or standard

IBA

1 reference

retrieved

21 June 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERL9&geneProductId=UniProtKB:Q9ERL9

determination method or standard

IBA

guanylate cyclase complex, soluble

determination method or standard

IBA

IEA

ISO

3 references

retrieved

21 June 2018

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERL9&geneProductId=UniProtKB:Q9ERL9

determination method or standard

ISO

retrieved

21 June 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERL9&geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

retrieved

21 June 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERL9&geneProductId=UniProtKB:Q9ERL9

determination method or standard

IBA

protein-containing complex

determination method or standard

ISO

1 reference

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

ISO

guanylate cyclase complex, soluble

determination method or standard

IEA

ISO

2 references

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

ISO

retrieved

14 February 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

glutamatergic synapse

determination method or standard

IDA

IMP

2 references

retrieved

14 February 2019

stated in

Nitric oxide/cGMP signaling via guanylyl cyclase isoform 1 modulates glutamate and GABA release in somatosensory cortex of mice

GOA

curator

SynGO

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IMP

retrieved

14 February 2019

stated in

Nitric oxide/cGMP signaling via guanylyl cyclase isoform 1 modulates glutamate and GABA release in somatosensory cortex of mice

GOA

curator

SynGO

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IDA

GABA-ergic synapse

determination method or standard

IDA

IMP

2 references

retrieved

14 February 2019

stated in

Nitric oxide/cGMP signaling via guanylyl cyclase isoform 1 modulates glutamate and GABA release in somatosensory cortex of mice

GOA

curator

SynGO

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IMP

retrieved

14 February 2019

stated in

Nitric oxide/cGMP signaling via guanylyl cyclase isoform 1 modulates glutamate and GABA release in somatosensory cortex of mice

GOA

curator

SynGO

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IDA

biological process

intracellular signal transduction

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

cyclic nucleotide biosynthetic process

determination method or standard

IEA

1 reference

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

regulation of blood pressure

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

Spare guanylyl cyclase NO receptors ensure high NO sensitivity in the vascular system

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IMP

cGMP biosynthetic process

determination method or standard

IEA

IMP

ISO

5 references

retrieved

14 February 2019

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

ISO

retrieved

14 February 2019

stated in

Spare guanylyl cyclase NO receptors ensure high NO sensitivity in the vascular system

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IMP

retrieved

14 February 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q9ERL9

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

retrieved

14 February 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

retrieved

14 February 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

relaxation of vascular associated smooth muscle

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

Spare guanylyl cyclase NO receptors ensure high NO sensitivity in the vascular system

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IMP

signal transduction

determination method or standard

IBA

1 reference

retrieved

21 June 2018

stated in

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERL9&geneProductId=UniProtKB:Q9ERL9

determination method or standard

IBA

cAMP biosynthetic process

determination method or standard

IEA

1 reference

retrieved

24 April 2018

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERL9&geneProductId=UniProtKB:Q9ERL9

determination method or standard

IEA

nitric oxide mediated signal transduction

determination method or standard

ISO

1 reference

retrieved

21 June 2018

stated in

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9ERL9&geneProductId=UniProtKB:Q9ERL9

determination method or standard

ISO

positive regulation of nitric oxide mediated signal transduction

determination method or standard

IMP

1 reference

retrieved

14 February 2019

stated in

Spare guanylyl cyclase NO receptors ensure high NO sensitivity in the vascular system

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IMP

retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission

determination method or standard

IDA

IMP

2 references

retrieved

14 February 2019

stated in

Nitric oxide/cGMP signaling via guanylyl cyclase isoform 1 modulates glutamate and GABA release in somatosensory cortex of mice

GOA

curator

SynGO

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IMP

retrieved

14 February 2019

stated in

Nitric oxide/cGMP signaling via guanylyl cyclase isoform 1 modulates glutamate and GABA release in somatosensory cortex of mice

GOA

curator

SynGO

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9ERL9

determination method or standard

IDA

has part(s)

Haem NO binding associated

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9ERL9

Adenylyl cyclase class-4/guanylyl cyclase, conserved site

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9ERL9

Adenylyl cyclase class-3/4/guanylyl cyclase

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q9ERL9

Identifiers

RefSeq protein ID

NP_068696

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

60596

NP_001343916

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

60596

NP_001343917

1 reference

stated in

NCBI Gene

retrieved

20 March 2022

Entrez Gene ID

60596

UniProt protein ID

Q9ERL9

1 reference

stated in

UniProt

retrieved

25 May 2022

UniProt protein ID

Q9ERL9

Ensembl protein ID

ENSMUSP00000048918

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000048918

ENSMUSP00000142138

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000142138

ENSMUSP00000141478

1 reference

stated in

ensembl Release 106

Ensembl protein ID

ENSMUSP00000141478

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q21495757&oldid=2023132769"