Phospholipase D family member 6 (Q21124923)

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mammalian protein found in Homo sapiens

• phospholipase D6
• PLD6
• mitochondrial phospholipase
• PLD 6
• mitoPLD
• choline phosphatase 6
• mitochondrial cardiolipin hydrolase
• phosphatidylcholine-hydrolyzing phospholipase D6
• protein zucchini homolog

edit

Language	Label	Description	Also known as
English	Phospholipase D family member 6	mammalian protein found in Homo sapiens	phospholipase D6 PLD6 mitochondrial phospholipase PLD 6 mitoPLD choline phosphatase 6 mitochondrial cardiolipin hydrolase phosphatidylcholine-hydrolyzing phospholipase D6 protein zucchini homolog

Statements

instance of

protein

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8N2A8

part of

Phospholipase D/Transphosphatidylase family

1 reference

based on heuristic

inferred from protein domain or family

Phospholipase D-like domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

found in taxon

Homo sapiens

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8N2A8

encoded by

PLD6

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8N2A8

molecular function

protein homodimerization activity

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

A common lipid links Mfn-mediated mitochondrial fusion and SNARE-regulated exocytosis

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IDA

metal ion binding

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

protein binding

determination method

IPI

1 reference

retrieved

8 April 2019

stated in

Mitoguardin Regulates Mitochondrial Fusion through MitoPLD and Is Required for Neuronal Homeostasis

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IPI

catalytic activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

InterPro

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

nuclease activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

endonuclease activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

hydrolase activity

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

cardiolipin hydrolase activity

determination method

IDA

TAS

3 references

retrieved

10 September 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N2A8&geneProductId=UniProtKB:Q8N2A8

determination method

TAS

retrieved

10 September 2018

stated in

A common lipid links Mfn-mediated mitochondrial fusion and SNARE-regulated exocytosis

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N2A8&geneProductId=UniProtKB:Q8N2A8

determination method

IDA

retrieved

10 September 2018

stated in

piRNA-associated germline nuage formation and spermatogenesis require MitoPLD profusogenic mitochondrial-surface lipid signaling

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N2A8&geneProductId=UniProtKB:Q8N2A8

determination method

IDA

cardiolipin hydrolase activity

determination method

IDA

2 references

retrieved

8 April 2019

stated in

A common lipid links Mfn-mediated mitochondrial fusion and SNARE-regulated exocytosis

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IDA

retrieved

8 April 2019

stated in

piRNA-associated germline nuage formation and spermatogenesis require MitoPLD profusogenic mitochondrial-surface lipid signaling

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IDA

cell component

integral component of membrane

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

membrane

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

mitochondrion

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

mitochondrial outer membrane

determination method

IDA

IEA

TAS

5 references

retrieved

27 March 2018

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N2A8&geneProductId=UniProtKB:Q8N2A8

determination method

TAS

retrieved

27 March 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N2A8&geneProductId=UniProtKB:Q8N2A8

determination method

IEA

retrieved

27 March 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N2A8&geneProductId=UniProtKB:Q8N2A8

determination method

IEA

retrieved

27 March 2018

stated in

A common lipid links Mfn-mediated mitochondrial fusion and SNARE-regulated exocytosis

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N2A8&geneProductId=UniProtKB:Q8N2A8

determination method

IDA

retrieved

27 March 2018

stated in

piRNA-associated germline nuage formation and spermatogenesis require MitoPLD profusogenic mitochondrial-surface lipid signaling

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N2A8&geneProductId=UniProtKB:Q8N2A8

determination method

IDA

mitochondrial outer membrane

determination method

IBA

IDA

IEA

TAS

6 references

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

TAS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

retrieved

8 April 2019

stated in

A common lipid links Mfn-mediated mitochondrial fusion and SNARE-regulated exocytosis

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IDA

retrieved

8 April 2019

stated in

piRNA-associated germline nuage formation and spermatogenesis require MitoPLD profusogenic mitochondrial-surface lipid signaling

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IDA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IBA

biological process

mitochondrial fusion

determination method

IMP

1 reference

retrieved

8 April 2019

stated in

A common lipid links Mfn-mediated mitochondrial fusion and SNARE-regulated exocytosis

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IMP

cell differentiation

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

lipid metabolism

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

P granule organization

determination method

ISS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

DNA methylation involved in gamete generation

determination method

ISS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

lipid catabolic process

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

spermatogenesis

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

spermatid development

determination method

ISS

IEA

2 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

positive regulation of mitochondrial fusion

determination method

IDA

1 reference

retrieved

8 April 2019

stated in

Phosphatidic acid (PA)-preferring phospholipase A1 regulates mitochondrial dynamics

GOA

curator

Mouse Genome Informatics

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IDA

nucleic acid phosphodiester bond hydrolysis

determination method

IEA

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Gene Ontology Consortium

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

piRNA metabolic process

determination method

IEA

ISS

2 references

retrieved

27 March 2018

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N2A8&geneProductId=UniProtKB:Q8N2A8

determination method

ISS

retrieved

27 March 2018

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q8N2A8&geneProductId=UniProtKB:Q8N2A8

determination method

IEA

meiosis

determination method

IEA

ISS

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

ISS

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

phosphatidic acid biosynthetic process

determination method

TAS

1 reference

retrieved

8 April 2019

stated in

GOA

curator

Reactome

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

TAS

piRNA metabolic process

determination method

IBA

IEA

ISS

3 references

retrieved

8 April 2019

stated in

GOA

curator

UniProt

UniProt protein ID

Q8N2A8

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

ISS

retrieved

8 April 2019

stated in

GOA

curator

Ensembl genome database project

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IEA

retrieved

8 April 2019

stated in

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

GOA

curator

GO Central

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q8N2A8

determination method

IBA

has part(s)

Phospholipase D/Transphosphatidylase

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8N2A8

Phospholipase D-like domain

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/Q8N2A8

Identifiers

RefSeq protein ID

NP_849158

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

201164

XP_016879799

1 reference

stated in

NCBI Gene

retrieved

30 May 2020

Entrez Gene ID

201164

UniProt protein ID

Q8N2A8

1 reference

stated in

UniProt

retrieved

13 November 2019

UniProt protein ID

Q8N2A8

Ensembl protein ID

ENSP00000317177

1 reference

stated in

Ensembl Release 99

Ensembl protein ID

ENSP00000317177

 

Sitelinks

Wikipedia(0 entries)

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Wikibooks(0 entries)

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Wikinews(0 entries)

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Wikiquote(0 entries)

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Wikisource(0 entries)

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Wikiversity(0 entries)

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Wikivoyage(0 entries)

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Wiktionary(0 entries)

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Multilingual sites(0 entries)

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Retrieved from "https://www.wikidata.org/w/index.php?title=Q21124923&oldid=2023005666"