Regulator of G protein signaling 2 (Q21173838)

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mammalian protein found in Homo sapiens

cell growth-inhibiting protein 31
G0/G1 switch regulatory protein 8
RGS2
cell growth-inhibiting gene 31 protein
regulator of G-protein signaling 2, 24kDa
regulator of G-protein signaling 2
G0 to G1 switch regulatory 8, 24kD

Language	Label	Description	Also known as
English	Regulator of G protein signaling 2	mammalian protein found in Homo sapiens	cell growth-inhibiting protein 31 G0/G1 switch regulatory protein 8 RGS2 cell growth-inhibiting gene 31 protein regulator of G-protein signaling 2, 24kDa regulator of G-protein signaling 2 G0 to G1 switch regulatory 8, 24kD

Statements

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

GTPase activator activity

determination method or standard

4 references

8 April 2019

Ca2+/Calmodulin reverses phosphatidylinositol 3,4, 5-trisphosphate-dependent inhibition of regulators of G protein-signaling GTPase-activating protein activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

8 April 2019

Structural Determinants of G-protein Subunit Selectivity by Regulator of G-protein Signaling 2 (RGS2)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

calmodulin binding

determination method or standard

1 reference

8 April 2019

Ca2+/Calmodulin reverses phosphatidylinositol 3,4, 5-trisphosphate-dependent inhibition of regulators of G protein-signaling GTPase-activating protein activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

protein binding

determination method or standard

5 references

8 April 2019

Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

8 April 2019

A proteome-scale map of the human interactome network

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

8 April 2019

Spinophilin/neurabin reciprocally regulate signaling intensity by G protein-coupled receptors

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

8 April 2019

Widespread macromolecular interaction perturbations in human genetic disorders

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

8 April 2019

A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

G-protein alpha-subunit binding

determination method or standard

1 reference

8 April 2019

Structural Determinants of G-protein Subunit Selectivity by Regulator of G-protein Signaling 2 (RGS2)

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

beta-tubulin binding

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

GTPase activity

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

neuron projection

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

8 April 2019

Mechanisms governing subcellular localization and function of human RGS2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

8 April 2019

Cytoplasmic, nuclear, and golgi localization of RGS proteins. Evidence for N-terminal and RGS domain sequences as intracellular targeting motifs

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

determination method or standard

3 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

8 April 2019

Mechanisms governing subcellular localization and function of human RGS2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

plasma membrane

determination method or standard

3 references

21 June 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41220&geneProductId=UniProtKB:P41220

determination method or standard

21 June 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41220&geneProductId=UniProtKB:P41220

determination method or standard

21 June 2018

Mechanisms governing subcellular localization and function of human RGS2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41220&geneProductId=UniProtKB:P41220

determination method or standard

determination method or standard

plasma membrane

determination method or standard

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

8 April 2019

Mechanisms governing subcellular localization and function of human RGS2

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

biological process

negative regulation of cAMP-mediated signaling

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

regulation of G protein-coupled receptor signaling pathway

determination method or standard

positive regulation of GTPase activity

determination method or standard

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

spermatogenesis

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

brown fat cell differentiation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

positive regulation of microtubule polymerization

determination method or standard

1 reference

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=P41220&geneProductId=UniProtKB:P41220

determination method or standard

relaxation of vascular associated smooth muscle

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

negative regulation of signal transduction

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

negative regulation of G protein-coupled receptor signaling pathway

determination method or standard

regulation of translation

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

response to amphetamine

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

brain development

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

positive regulation of neuron projection development

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

negative regulation of translation

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

response to ethanol

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

maternal process involved in female pregnancy

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

negative regulation of cell growth involved in cardiac muscle cell development

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

negative regulation of glycine import across plasma membrane

determination method or standard

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

G protein-coupled receptor signaling pathway

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P41220

determination method or standard

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P41220

Identifiers

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000235382

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000235382

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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