Impaired Glucocorticoid Suppression of TGFβ Signaling in Human Omental Adipose Tissues Limits Adipogenesis and May Promote Fibrosis (Q90365735)

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scientific article published on 07 December 2018

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English	Impaired Glucocorticoid Suppression of TGFβ Signaling in Human Omental Adipose Tissues Limits Adipogenesis and May Promote Fibrosis	scientific article published on 07 December 2018

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scholarly article

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13 April 2020

Impaired Glucocorticoid Suppression of TGFβ Signaling in Human Omental Adipose Tissues Limits Adipogenesis and May Promote Fibrosis (English)

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13 April 2020

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1

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13 April 2020

author name string

R Taylor Pickering

2

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13 April 2020

Varuna Shibad

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13 April 2020

Yuanyuan Wu

4

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13 April 2020

Kalypso Karastergiou

5

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13 April 2020

Mike Jager

6

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13 April 2020

Matthew D Layne

7

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13 April 2020

Susan K Fried

8

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13 April 2020

publication date

7 December 2018

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13 April 2020

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13 April 2020

68

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13 April 2020

3

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13 April 2020

587-597

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13 April 2020

describes a project that uses

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6385749/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Promoting effect of glucocorticoids on the differentiation of human adipocyte precursor cells cultured in a chemically defined medium

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

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Transforming growth factor beta (TGF-beta) inhibits the differentiation of human adipocyte precursor cells in primary culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

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An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lipoprotein lipase regulation by insulin and glucocorticoid in subcutaneous and omental adipose tissues of obese women and men.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Omental and Subcutaneous Adipose Tissues of Obese Subjects Release Interleukin-6: Depot Difference and Regulation by Glucocorticoid1

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

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Roles of autocrine TGF-beta receptor and Smad signaling in adipocyte differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fat depot origin affects adipogenesis in primary cultured and cloned human preadipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of proliferation and differentiation capacity of human adipocyte precursor cells from the omental and subcutaneous adipose tissue depot of obese subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of glucocorticoid receptor function via phosphorylation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Macrophage-secreted factors impair human adipogenesis: involvement of proinflammatory state in preadipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

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Macrophage infiltration into omental versus subcutaneous fat across different populations: effect of regional adiposity and the comorbidities of obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Remodeling Phenotype of Human Subcutaneous Adipose Tissue Macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

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Macrophage-secreted factors promote a profibrotic phenotype in human preadipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired preadipocyte differentiation in human abdominal obesity: role of Wnt, tumor necrosis factor-alpha, and inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activated Ask1-MKK4-p38MAPK/JNK stress signaling pathway in human omental fat tissue may link macrophage infiltration to whole-body Insulin sensitivity

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcription factor Smad3 is required for the inhibition of adipogenesis by retinoic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of genes related to glucocorticoid action in human subcutaneous and omental adipose tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activin a plays a critical role in proliferation and differentiation of human adipose progenitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibrosis in human adipose tissue: composition, distribution, and link with lipid metabolism and fat mass loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathways regulated by glucocorticoids in omental and subcutaneous human adipose tissues: a microarray study

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGFbeta family members are key mediators in the induction of myofibroblast phenotype of human adipose tissue progenitor cells by macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrinsic differences in adipocyte precursor cells from different white fat depots.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adipose tissue heterogeneity: implication of depot differences in adipose tissue for obesity complications

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human but not mouse adipogenesis is critically dependent on LMO3

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prolonged efficiency of siRNA-mediated gene silencing in primary cultures of human preadipocytes and adipocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucocorticoids recruit Tgfbr3 and Smad1 to shift transforming growth factor-β signaling from the Tgfbr1/Smad2/3 axis to the Acvrl1/Smad1 axis in lung fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glucocorticoid receptor, not the mineralocorticoid receptor, plays the dominant role in adipogenesis and adipokine production in human adipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimal protocol for the differentiation and metabolic analysis of human adipose stromal cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ectodomain shedding of TβRIII is required for TβRIII-mediated suppression of TGF-β signaling and breast cancer migration and invasion

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammation and the depot-specific secretome of human preadipocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Omental adipose tissue fibrosis and insulin resistance in severe obesity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibrosis-streaks and splatters: Some things are not always what they seem to be.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinoic Acid Mediates Visceral-Specific Adipogenic Defects of Human Adipose-Derived Stem Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of the Bioavailability of TGF-β and TGF-β-Related Proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 induces impairment in human subcutaneous adipogenesis in obesity-associated insulin resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relevance of omental pericellular adipose tissue collagen in the pathophysiology of human abdominal obesity and related cardiometabolic risk

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A glucocorticoid- and diet-responsive pathway toggles adipocyte precursor cell activity in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-fat diet-induced obesity regulates MMP3 to modulate depot- and sex-dependent adipose expansion in C57BL/6J mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depot Dependent Effects of Dexamethasone on Gene Expression in Human Omental and Abdominal Subcutaneous Adipose Tissues from Obese Women

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adipose tissue macrophages impair preadipocyte differentiation in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A PDGFRα-Mediated Switch toward CD9high Adipocyte Progenitors Controls Obesity-Induced Adipose Tissue Fibrosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinoids Regulate Adipogenesis Involving the TGFβ/SMAD and Wnt/β-Catenin Pathways in Human Bone Marrow Mesenchymal Stem Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human Adipose Mesenchymal Cells Inhibit Melanocyte Differentiation and the Pigmentation of Human Skin via Increased Expression of TGF-β1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dually modified transmembrane proteoglycans in development and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aortic carboxypeptidase-like protein enhances adipose tissue stromal progenitor differentiation into myofibroblasts and is upregulated in fibrotic white adipose tissue.

1 reference

https://pubmed.ncbi.nlm.nih.gov/30530781

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2337/DB18-0955

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530781%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530781%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30530781%20AND%20SRC:MED&resulttype=core&format=json

13 April 2020

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