Prediction of in vivo interaction between triazolam and erythromycin based on in vitro studies using human liver microsomes and recombinant human CYP3A4 (Q73933454)

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scientific article published on 01 April 2000

Language	Label	Description	Also known as
English	Prediction of in vivo interaction between triazolam and erythromycin based on in vitro studies using human liver microsomes and recombinant human CYP3A4	scientific article published on 01 April 2000

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scholarly article

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10870985%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Prediction of in vivo interaction between triazolam and erythromycin based on in vitro studies using human liver microsomes and recombinant human CYP3A4 (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10870985%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

1 reference

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author name string

S Kanamitsu

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10870985%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

K Ito

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10870985%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

C E Green

3

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10870985%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

C A Tyson

4

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Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10870985%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

N Shimada

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10870985%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Y Sugiyama

6

1 reference

Europe PubMed Central

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7 November 2019

publication date

1 April 2000

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10870985%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Pharmaceutical Research

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10870985%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

17

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10870985%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10870985%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

419-426

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10870985%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

Oxidation of midazolam and triazolam by human liver cytochrome P450IIIA4.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of pharmacokinetic alterations caused by drug-drug interactions: metabolic interaction in the liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics of suicide substrates. Practical procedures for determining parameters

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic drug interactions of macrolides

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single oral dose pharmacokinetics of erythromycin and roxithromycin and the effects of chronic dosing

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triazolam disposition

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of human CYP3A catalyzed 1'-hydroxy midazolam formation by ketoconazole, nifedipine, erythromycin, cimetidine, and nizatidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A potent inhibitory effect of erythromycin and other macrolide antibiotics on the mono-N-dealkylation metabolism of disopyramide with human liver microsomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pharmacokinetic analysis program (multi) for microcomputer

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of the inhibition of cytochrome P-450-mediated drug oxidation by therapeutic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative prediction of in vivo drug clearance and drug interactions from in vitro data on metabolism, together with binding and transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triazolam biotransformation by human liver microsomes in vitro: effects of metabolic inhibitors and clinical confirmation of a predicted interaction with ketoconazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo drug interactions involving human CYP3A.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of (E)-5-(2-bromovinyl)uracil on the catabolism and antitumor activity of 5-fluorouracil in rats and leukemic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pharmacokinetic drug interaction between erythromycin and triazolam

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

First-pass metabolism of cyclosporin by the gut

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Lethal drug interactions of sorivudine, a new antiviral drug, with oral 5-fluorouracil prodrugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Turnover of membrane proteins: kinetics of induction and degradation of seven forms of rat liver microsomal cytochrome P-450, NADPH-cytochrome P-450 reductase, and epoxide hydrolase

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prediction of in vivo drug-drug interactions based on mechanism-based inhibition from in vitro data: inhibition of 5-fluorouracil metabolism by (E)-5-(2-Bromovinyl)uracil

1 reference

https://pubmed.ncbi.nlm.nih.gov/10870985

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1007572803027

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10870985%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10870985%20AND%20SRC:MED&resulttype=core&format=json

7 November 2019

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