Interferon alpha/beta-mediated inhibition and promotion of interferon gamma: STAT1 resolves a paradox (Q73956048)

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8 November 2019

title

Interferon alpha/beta-mediated inhibition and promotion of interferon gamma: STAT1 resolves a paradox (English)

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8 November 2019

K B Nguyen

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8 November 2019

L P Cousens

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8 November 2019

L A Doughty

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8 November 2019

G C Pien

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8 November 2019

J E Durbin

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8 November 2019

C A Biron

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8 November 2019

publication date

1 July 2000

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8 November 2019

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8 November 2019

volume

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8 November 2019

issue

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8 November 2019

page(s)

70-76

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Natural killer cells in antiviral defense: function and regulation by innate cytokines

8 November 2019

cites work

1 reference

7 January 2021

Role of early cytokines, including alpha and beta interferons (IFN-alpha/beta), in innate and adaptive immune responses to viral infections

1 reference

7 January 2021

Initial and innate responses to viral infections--pattern setting in immunity or disease

1 reference

7 January 2021

Induction of bystander T cell proliferation by viruses and type I interferon in vivo

1 reference

7 January 2021

Type I interferons keep activated T cells alive

1 reference

7 January 2021

Requirement for natural killer cell-produced interferon gamma in defense against murine cytomegalovirus infection and enhancement of this defense pathway by interleukin 12 administration

1 reference

7 January 2021

Characterization of early cytokine responses and an interleukin (IL)-6-dependent pathway of endogenous glucocorticoid induction during murine cytomegalovirus infection

1 reference

7 January 2021

Compartmental differences in NK cell responsiveness to IL-12 during lymphocytic choriomeningitis virus infection

1 reference

7 January 2021

Interferon-alpha/beta inhibition of interleukin 12 and interferon-gamma production in vitro and endogenously during viral infection

1 reference

7 January 2021

Selective expression of an interleukin-12 receptor component by human T helper 1 cells

1 reference

7 January 2021

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

1 reference

7 January 2021

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

1 reference

7 January 2021

Regulation of c-myc expression by IFN-gamma through Stat1-dependent and -independent pathways.

1 reference

7 January 2021

Stat1 as a component of tumor necrosis factor alpha receptor 1-TRADD signaling complex to inhibit NF-kappaB activation

1 reference

7 January 2021

Cooperative DNA binding and sequence-selective recognition conferred by the STAT amino-terminal domain

1 reference

7 January 2021

Roles of Protein-tyrosine Phosphatases in Stat1 -mediated Cell Signaling

1 reference

7 January 2021

Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway

1 reference

7 January 2021

The suppressor of cytokine signaling (SOCS) 1 and SOCS3 but not SOCS2 proteins inhibit interferon-mediated antiviral and antiproliferative activities

1 reference

7 January 2021

SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality

1 reference

7 January 2021

SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine.

1 reference

7 January 2021

A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1.

1 reference

7 January 2021

Activation-induced inhibition of interleukin 6-mediated T cell survival and signal transducer and activator of transcription 1 signaling

1 reference

7 January 2021

Two roads diverged: interferon alpha/beta- and interleukin 12-mediated pathways in promoting T cell interferon gamma responses during viral infection

1 reference

7 January 2021

Mechanism of interleukin 12-mediated toxicities during experimental viral infections: role of tumor necrosis factor and glucocorticoids

1 reference

7 January 2021

Agonist and antagonist effects of interferon alpha and beta on activation of human macrophages. Two classes of interferon gamma receptors and blockade of the high-affinity sites by interferon alpha or beta

1 reference

7 January 2021

Induction and exhaustion of lymphocytic choriomeningitis virus-specific cytotoxic T lymphocytes visualized using soluble tetrameric major histocompatibility complex class I-peptide complexes.

1 reference

7 January 2021

Interferon gamma plays a critical role in induced cell death of effector T cell: a possible third mechanism of self-tolerance

1 reference

7 January 2021

Functional role of type I and type II interferons in antiviral defense

1 reference

7 January 2021

T helper type 2 cell differentiation occurs in the presence of interleukin 12 receptor beta2 chain expression and signaling

1 reference

7 January 2021

Identifiers

DOI

10.1038/76940

1 reference

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8 November 2019

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