Detection and quantification of remote microglial activation in rodent models of focal ischaemia using the TSPO radioligand CLINDE (Q59858978)

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scientific article published on 03 September 2010

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English	Detection and quantification of remote microglial activation in rodent models of focal ischaemia using the TSPO radioligand CLINDE	scientific article published on 03 September 2010

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13 February 2020

Detection and quantification of remote microglial activation in rodent models of focal ischaemia using the TSPO radioligand CLINDE (English)

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13 February 2020

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Nicolas Arlicot

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13 February 2020

Denis Guilloteau

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13 February 2020

Myriam Bernaudin

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13 February 2020

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13 February 2020

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Edwige Petit

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13 February 2020

Andrew Katsifis

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13 February 2020

Jérôme Toutain

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13 February 2020

Didier Divoux

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13 February 2020

Sylvie Bodard

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13 February 2020

Simon Roussel

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13 February 2020

publication date

3 September 2010

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13 February 2020

European Journal of Nuclear Medicine and Molecular Imaging

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13 February 2020

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13 February 2020

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13 February 2020

2371-2380

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13 February 2020

Inflammatory response after ischemic stroke: a USPIO-enhanced MRI study in patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/20814674

12 December 2020

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Peripheral-type benzodiazepine receptor: structure and function of a cholesterol-binding protein in steroid and bile acid biosynthesis

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The role of diaschisis in stroke recovery

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12 December 2020

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The positron emission tomography ligand DAA1106 binds with high affinity to activated microglia in human neurological disorders

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A comparative autoradiography study in post mortem whole hemisphere human brain slices taken from Alzheimer patients and age-matched controls using two radiolabelled DAA1106 analogues with high affinity to the peripheral benzodiazepine receptor (PBR

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Thalamic metbolism and corticospinal tract integrity determine motor recovery in stroke

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The peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: from pathology to imaging

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Synthesis of the enantiomers of [N-methyl-11C]PK 11195 and comparison of their behaviours as radioligands for PK binding sites in rats

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Glial responses, clusterin, and complement in permanent focal cerebral ischemia in the mouse

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12 December 2020

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The development of stroke therapeutics: promising mechanisms and translational challenges

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Reversible middle cerebral artery occlusion without craniectomy in rats

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Evaluation of CLINDE as potent translocator protein (18 kDa) SPECT radiotracer reflecting the degree of neuroinflammation in a rat model of microglial activation

1 reference

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Behavioral deficits after distal focal cerebral ischemia in mice: Usefulness of adhesive removal test.

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Inflammation as therapeutic objective in stroke

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Imaging brain inflammation with [(11)C]PK11195 by PET and induction of the peripheral-type benzodiazepine receptor after transient focal ischemia in rats

1 reference

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Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function

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MRI detection of secondary damage after stroke: chronic iron accumulation in the thalamus of the rat brain

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Evaluation of a radiolabelled peripheral benzodiazepine receptor ligand in the central nervous system inflammation of experimental autoimmune encephalomyelitis: a possible probe for imaging multiple sclerosis

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Specific ligands of the peripheral benzodiazepine receptor induce apoptosis and cell cycle arrest in human esophageal cancer cells

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Detection of viable cortical neurons using benzodiazepine receptor imaging after reversible focal ischaemia in rats: comparison with regional cerebral blood flow

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12 December 2020

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Peripheral benzodiazepine receptors in patients with chronic schizophrenia: a PET study with [11C]DAA1106.

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Initial evaluation of 11C-DPA-713, a novel TSPO PET ligand, in humans

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PET imaging with [11C]PBR28 can localize and quantify upregulated peripheral benzodiazepine receptors associated with cerebral ischemia in rat.

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Worldwide stroke incidence and early case fatality reported in 56 population-based studies: a systematic review

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Time course of microglia activation and apoptosis in various brain regions after permanent focal cerebral ischemia in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20814674

12 December 2020

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Characterization of the cholesterol recognition amino acid consensus sequence of the peripheral-type benzodiazepine receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20814674

12 December 2020

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Intrinsic activated microglia map to the peri-infarct zone in the subacute phase of ischemic stroke.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20814674

12 December 2020

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Chronological atrophy after transient middle cerebral artery occlusion in rats

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12 December 2020

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11C-DPA-713: a novel peripheral benzodiazepine receptor PET ligand for in vivo imaging of neuroinflammation

1 reference

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PET imaging of the peripheral benzodiazepine receptor: monitoring disease progression and therapy response in neurodegenerative disorders

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Adventures in the pathophysiology of brain ischemia: penumbra, gene expression, neuroprotection: the 2002 Thomas Willis Lecture

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Peripheral benzodiazepine receptors are colocalized with activated microglia following transient global forebrain ischemia in the rat

1 reference

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Thalamic microglial activation in ischemic stroke detected in vivo by PET and [11C]PK1195.

1 reference

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Tumor necrosis factor-α expression in areas of remote degeneration following middle cerebral artery occlusion of the rat

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[3H]PK 11195 and the localisation of secondary thalamic lesions following focal ischaemia in rat motor cortex

1 reference

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12 December 2020

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1 reference

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Evaluation of the PBR/TSPO radioligand [(18)F]DPA-714 in a rat model of focal cerebral ischemia

1 reference

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12 December 2020

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Pharmacological evaluation of [123I]-CLINDE: a radioiodinated imidazopyridine-3-acetamide for the study of peripheral benzodiazepine binding sites (PBBS).

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Radiolabelled molecules for imaging the translocator protein (18 kDa) using positron emission tomography

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12 December 2020

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Labelling of "Peripheral-Type" Benzodiazepine Binding Sites in the Rat Brain By Using [3H]PK 11195, an Isoquinoline Carboxamide Derivative: Kinetic Studies and Autoradiographic Localization

1 reference

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1 reference

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1 reference

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1 reference

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Identifiers

10.1007/S00259-010-1598-7

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Europe PubMed Central

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13 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20814674%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

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