Excessive Activation of Poly(ADP-Ribose) Polymerase Contributes to Inherited Photoreceptor Degeneration in the Retinal Degeneration 1 Mouse (Q59209075)

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scientific article published on 01 September 2007

Language	Label	Description	Also known as
English	Excessive Activation of Poly(ADP-Ribose) Polymerase Contributes to Inherited Photoreceptor Degeneration in the Retinal Degeneration 1 Mouse	scientific article published on 01 September 2007

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17881537%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Excessive activation of poly(ADP-ribose) polymerase contributes to inherited photoreceptor degeneration in the retinal degeneration 1 mouse (English)

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7 January 2020

photoreceptor protein

0 references

retinal degeneration

1 reference

based on heuristic

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François Paquet-Durand

1

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7 January 2020

2

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7 January 2020

Stefanie M. Hauck

8

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7 January 2020

7

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Marius Ueffing

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7 January 2020

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Tanuja Talukdar

3

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7 January 2020

Leif E Johnson

4

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7 January 2020

Seifollah Azadi

5

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7 January 2020

Theo van Veen

6

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7 January 2020

Per A R Ekström

9

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7 January 2020

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publication date

1 September 2007

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7 January 2020

Journal of Neuroscience

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7 January 2020

27

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7 January 2020

38

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7 January 2020

10311-10319

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7 January 2020

Quality control by DNA repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium overload triggers rod photoreceptor apoptotic cell death in chemical-induced and inherited retinal degenerations

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Post-treatment at 12 or 18 hours with 3-aminobenzamide ameliorates retinal ischemia-reperfusion damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of poly(ADP-ribose) polymerase activation in oxidatively stressed cells and tissues using biotinylated NAD substrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-3 inhibitor transiently delays inherited retinal degeneration in C3H mice carrying the rd gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel phenanthridinone inhibitors of poly (adenosine 5'-diphosphate-ribose) synthetase: potent cytoprotective and antishock agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of caspase-3 during degeneration of the outer nuclear layer in the rd mouse retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD+ depletion and cell death induced by oxidative stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-independent photoreceptor apoptosis in mouse models of retinal degeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-3 in postnatal retinal development and degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inherited retinal degenerations: therapeutic prospects

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose) polymerase activity contributes to peroxynitrite-induced spinal cord neuronal cell death in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased glutathione transferase levels in rd1/rd1 mouse retina: replenishment protects photoreceptors in retinal explants

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear poly(ADP-ribose) polymerase-1 rapidly triggers mitochondrial dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of poly(ADP-ribose) metabolism by poly(ADP-ribose) glycohydrolase: where and when?

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mediation of cell death by poly(ADP-ribose) polymerase-1.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential modification of phosducin protein in degenerating rd1 retina is associated with constitutively active Ca2+/calmodulin kinase II in rod outer segments

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinitis pigmentosa: visual function and multidisciplinary management

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis-inducing factor triggered by poly(ADP-ribose) polymerase and Bid mediates neuronal cell death after oxygen-glucose deprivation and focal cerebral ischemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calpain is activated in degenerating photoreceptors in the rd1 mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation and increased phosphorylation of protein kinase C (PKC) delta, mu and theta in the degenerating rd1 mouse retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose): novel functions for an old molecule

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of PARP activity attenuates poly(ADP-ribosyl)ation but offers only partial neuroprotection against NMDA-induced cell death in the rat retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neither energy collapse nor transcription underlie in vitro neurotoxicity of poly(ADP-ribose) polymerase hyper-activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in retinal degeneration involves cross-talk between apoptosis-inducing factor (AIF) and caspase-12 and is blocked by calpain inhibitors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis-inducing factor mediates poly(ADP-ribose) (PAR) polymer-induced cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose) (PAR) polymer is a death signal

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly (ADP-ribose) polymerase inhibitor 3-aminobenzamide rescues N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in Sprague-Dawley rats through preservation of nuclear factor-kappaB activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CNTF+BDNF treatment and neuroprotective pathways in the rd1 mouse retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calpain activity in retinal degeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Decreased PARP-1 levels accelerate embryonic lethality but attenuate neuronal apoptosis in DNA polymerase beta-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis-inducing factor: a matter of neuron life and death

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significant photoreceptor rescue by treatment with a combination of antioxidants in an animal model for retinal degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinal degeneration in the rd mouse is caused by a defect in the beta subunit of rod cGMP-phosphodiesterase

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic GMP can increase rod outer-segment light-sensitive current 10-fold without delay of excitation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic guanosine monophosphate: elevation in degenerating photoreceptor cells of the C3H mouse retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose) polymerase inhibitors preserve oxidized nicotinamide adenine dinucleotide and adenosine 5'-triphosphate pools in DNA-damaged cells: mechanism of stimulation of unscheduled DNA synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell death during differentiation of the retina in the mouse.

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential effect of the rd mutation on rods and cones in the mouse retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutation spectrum of the gene encoding the beta subunit of rod phosphodiesterase among patients with autosomal recessive retinitis pigmentosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poly(ADP-ribose) polymerase is a catalytic dimer and the automodification reaction is intermolecular

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis: final common pathway of photoreceptor death in rd, rds, and rhodopsin mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and identification of a proteinase from calf thymus that cleaves poly(ADP-ribose) polymerase and histone H1

1 reference

https://pubmed.ncbi.nlm.nih.gov/17881537

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.1514-07.2007

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17881537%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17881537%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17881537%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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