Clinical applications of liquid biopsy as prognostic and predictive biomarkers in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA (Q57161777)

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scientific article published on 03 September 2018

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English	Clinical applications of liquid biopsy as prognostic and predictive biomarkers in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA	scientific article published on 03 September 2018

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scholarly article

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21 April 2020

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11 December 2020

19 July 2022

23 July 2022

Clinical applications of liquid biopsy as prognostic and predictive biomarkers in hepatocellular carcinoma: circulating tumor cells and circulating tumor DNA (English)

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21 April 2020

hepatocellular carcinoma

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7 August 2019

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7 August 2019

tumor biomarker

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7 August 2019

cell-free tumour DNA

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11 December 2020

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based on heuristic

inferred from title

7

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21 April 2020

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Jie Li

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Xu Han

2

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Xiaona Yu

3

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Zongzhen Xu

4

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Guangsheng Yang

5

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Bingqi Liu

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3 September 2018

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23 July 2022

Journal of Experimental & Clinical Cancer Research

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19 June 2019

2 August 2019

7 August 2019

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11 December 2020

19 July 2022

23 July 2022

37

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21 April 2020

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21 April 2020

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3 April 2019

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Europe PubMed Central

19 July 2022

Europe PubMed Central

23 July 2022

on focus list of Wikimedia project

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The diagnostic value of assays for circulating tumor cells in hepatocellular carcinoma: A meta-analysis

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Circulating tumor DNA profiling reveals clonal evolution and real-time disease progression in advanced hepatocellular carcinoma

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Application of circulating tumor DNA in prospective clinical oncology trials - standardization of preanalytical conditions.

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An RNA-based signature enables high specificity detection of circulating tumor cells in hepatocellular carcinoma.

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Circulating tumor cell detection in hepatocellular carcinoma based on karyoplasmic ratios using imaging flow cytometry

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Detecting Circulating Tumor DNA in Hepatocellular Carcinoma Patients Using Droplet Digital PCR Is Feasible and Reflects Intratumoral Heterogeneity

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Plasma Circulating Cell-free DNA Integrity as a Promising Biomarker for Diagnosis and Surveillance in Patients with Hepatocellular Carcinoma

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Microfluidic chip for isolation of viable circulating tumor cells of hepatocellular carcinoma for their culture and drug sensitivity assay

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Circulating tumour cells as biomarkers for evaluating cryosurgery on unresectable hepatocellular carcinoma

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Aptamer-Mediated Transparent-Biocompatible Nanostructured Surfaces for Hepotocellular Circulating Tumor Cells Enrichment

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Association of preoperative EpCAM Circulating Tumor Cells and peripheral Treg cell levels with early recurrence of hepatocellular carcinoma following radical hepatic resection.

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Cell-free DNA (cfDNA): Clinical Significance and Utility in Cancer Shaped By Emerging Technologies

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Liquid Biopsy of Hepatocellular Carcinoma: Circulating Tumor-Derived Biomarkers

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AFP mRNA level in enriched circulating tumor cells from hepatocellular carcinoma patient blood samples is a pivotal predictive marker for metastasis.

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Imagestream detection and characterisation of circulating tumour cells - A liquid biopsy for hepatocellular carcinoma?

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pERK/pAkt phenotyping in circulating tumor cells as a biomarker for sorafenib efficacy in patients with advanced hepatocellular carcinoma

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XRCC1 rs25487 genetic variant and TP53 mutation at codon 249 predict clinical outcomes of hepatitis B virus-related hepatocellular carcinoma after hepatectomy: A cohort study for 10 years' follow up.

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Immunological landscape and immunotherapy of hepatocellular carcinoma

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Increased Expression of Circulating Cancer Stem Cell Markers During the Perioperative Period Predicts Early Recurrence After Curative Resection of Hepatocellular Carcinoma.

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Aberrant DNA methylation of G-protein-coupled bile acid receptor Gpbar1 (TGR5) is a potential biomarker for hepatitis B Virus associated hepatocellular carcinoma.

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Evaluation of INK4A promoter methylation using pyrosequencing and circulating cell-free DNA from patients with hepatocellular carcinoma

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Real-time liquid biopsy in cancer patients: fact or fiction?

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Epithelial-mesenchymal transition markers expressed in circulating tumor cells in hepatocellular carcinoma patients with different stages of disease

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Plasma is a better source of tumor-derived circulating cell-free DNA than serum for the detection of EGFR alterations in lung tumor patients

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Presence of EpCAM-positive circulating tumor cells as biomarker for systemic disease strongly correlates to survival in patients with hepatocellular carcinoma

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Circulating stem cell-like epithelial cell adhesion molecule-positive tumor cells indicate poor prognosis of hepatocellular carcinoma after curative resection

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Management of hepatocellular carcinoma: An update

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Efficient detection of hepatocellular carcinoma by a hybrid blood test of epigenetic and classical protein markers

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Non-viral causes of hepatocellular carcinoma

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Significance of Circulating Tumor Cells Detected by the CellSearch System in Patients with Metastatic Breast Colorectal and Prostate Cancer

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Concordance of DNA methylation pattern in plasma and tumor DNA of Egyptian hepatocellular carcinoma patients

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MicroRNA classifiers for predicting prognosis of squamous cell lung cancer

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Alpha-fetoprotein and human telomerase reverse transcriptase mRNA levels in peripheral blood of patients with hepatocellular carcinoma.

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Circulating mutant DNA to assess tumor dynamics

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Diagnosis and Treatment of Hepatocellular Carcinoma

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Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: a validation study of the CellSearch system.

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2 November 2018

Elevated levels of circulating cell-free DNA in the blood of patients with hepatitis C virus-associated hepatocellular carcinoma.

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2 November 2018

Circulating nucleic acids (CNAs) and cancer--a survey

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2 November 2018

Circulating DNA and DNase activity in human blood

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2 November 2018

High frequency of promoter hypermethylation of RASSF1A in tumor and plasma of patients with hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6122633

2 November 2018

Hepatocellular carcinoma in cirrhosis: incidence and risk factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6122633

2 November 2018

Clinical significance of alpha-fetoprotein mRNA in blood of patients with hepatocellular carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6122633

2 November 2018

Does the presence of circulating hepatocellular carcinoma cells indicate a risk of recurrence after resection?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6122633

2 November 2018

Impact of cytomorphological detection of circulating tumor cells in patients with liver cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6122633

2 November 2018

Frequent EpCam protein expression in human carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6122633

2 November 2018

Evaluation of MAGE-1 and MAGE-3 as tumour-specific markers to detect blood dissemination of hepatocellular carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6122633

2 November 2018

Prospective evaluation of circulating hepatocytes by alpha-fetoprotein messenger RNA in patients with hepatocellular carcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6122633

2 November 2018

Quantitation of genomic DNA in plasma and serum samples: higher concentrations of genomic DNA found in serum than in plasma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6122633

2 November 2018

Isolation by size of epithelial tumor cells : a new method for the immunomorphological and molecular characterization of circulatingtumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6122633

2 November 2018

Highly-sensitive identification of alpha-fetoprotein mRNA in circulating peripheral blood of hepatocellular carcinoma patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6122633

2 November 2018

Free DNA in the serum of rheumatoid arthritis patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6122633

2 November 2018

CEA, AFP and Other Potential Tumor Markers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6122633

2 November 2018

Circulating biomarkers in hepatocellular carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6122633

30 November 2018

Detection of alpha-fetoprotein mRNA, an indicator of hematogenous spreading hepatocellular carcinoma, in the circulation: a possible predictor of metastatic hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30176913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prospective Evaluation of Circulating Hepatocytes by Alpha-Fetoprotein mRNA in Humans During Liver Surgery

1 reference

https://pubmed.ncbi.nlm.nih.gov/30176913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presence of alpha-fetoprotein mRNA in blood correlates with outcome in patients with hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30176913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Frequent p15 promoter methylation in tumor and peripheral blood from hepatocellular carcinoma patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/30176913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulating tumor cell mRNAs in peripheral blood from hepatocellular carcinoma patients under radiotherapy, surgical resection or chemotherapy: a quantitative evaluation

1 reference

https://pubmed.ncbi.nlm.nih.gov/30176913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative analysis of tumor-derived methylated p16INK4a sequences in plasma, serum, and blood cells of hepatocellular carcinoma patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/30176913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in Concentration of DNA in Serum and Plasma during Storage of Blood Samples

1 reference

https://pubmed.ncbi.nlm.nih.gov/30176913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prognostic value of circulating plasma DNA level and its allelic imbalance on chromosome 8p in patients with hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30176913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The clinical significance of circulating tumor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/30176913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predicting hepatocellular carcinoma by detection of aberrant promoter methylation in serum DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/30176913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative analysis of circulating methylated DNA as a biomarker for hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30176913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylation of tumor associated genes in tissue and plasma samples from liver disease patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/30176913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitation of plasma circulating DNA using quantitative PCR for the detection of hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30176913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Values of circulating GPC-3 mRNA and alpha-fetoprotein in detecting patients with hepatocellular carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/30176913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical significance of EpCAM mRNA-positive circulating tumor cells in hepatocellular carcinoma by an optimized negative enrichment and qRT-PCR-based platform

1 reference

https://pubmed.ncbi.nlm.nih.gov/30176913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer biomarkers: Written in blood

1 reference

https://pubmed.ncbi.nlm.nih.gov/30176913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S13046-018-0893-1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30176913%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

Dimensions Publication ID

1 reference

9 September 2019

https://scigraph.springernature.com/pub.10.1186/s13046-018-0893-1

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30176913%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:30176913%20AND%20SRC:MED&resulttype=core&format=json

21 April 2020

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