Mycophenolic acid-mediated suppression of human CD4+ T cells: more than mere guanine nucleotide deprivation (Q56899012)

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scientific article published on 01 March 2011

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English	Mycophenolic acid-mediated suppression of human CD4+ T cells: more than mere guanine nucleotide deprivation	scientific article published on 01 March 2011

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23 January 2020

Mycophenolic acid-mediated suppression of human CD4+ T cells: more than mere guanine nucleotide deprivation (English)

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23 January 2020

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23 January 2020

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R L Smeets

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23 January 2020

H J P M Koenen

3

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23 January 2020

P M Vink

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23 January 2020

J Wagenaars

5

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23 January 2020

A M H Boots

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23 January 2020

I Joosten

7

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23 January 2020

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1 March 2011

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23 January 2020

American Journal of Transplantation

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23 January 2020

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23 January 2020

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23 January 2020

439-449

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23 January 2020

What is the value of mycophenolate mofetil as induction and maintenance therapy in lupus nephritis?

1 reference

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21 January 2018

Constitutively active STAT5 variants induce growth and survival of hematopoietic cells through a PI 3-kinase/Akt dependent pathway.

1 reference

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Conversion from calcineurin inhibitor to mycophenolate mofetil-based immunosuppression changes the frequency and phenotype of CD4+FOXP3+ regulatory T cells

1 reference

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Revving the engine: signal transduction fuels T cell activation

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Timing and tuning of CD27-CD70 interactions: the impact of signal strength in setting the balance between adaptive responses and immunopathology

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Signalling via CD70, a member of the TNF family, regulates T cell functions

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Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling

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A late, prolonged activation of the phosphatidylinositol 3-kinase pathway is required for T cell proliferation

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Activated STAT5 proteins induce activation of the PI 3-kinase/Akt and Ras/MAPK pathways via the Gab2 scaffolding adapter

1 reference

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STAT5 is essential for Akt/p70S6 kinase activity during IL-2-induced lymphocyte proliferation

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Human CD25highFoxp3pos regulatory T cells differentiate into IL-17-producing cells

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Mycophenolic acid increases apoptosis, lysosomes and lipid droplets in human lymphoid and monocytic cell lines

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The Ki-67 protein: from the known and the unknown

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Overexpression of CD70 and overstimulation of IgG synthesis by lupus T cells and T cells treated with DNA methylation inhibitors

1 reference

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21 January 2018

Mycophenolic acid inhibits IL-2-dependent T cell proliferation, but not IL-2-dependent survival and sensitization to apoptosis

1 reference

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21 January 2018

Lymphocyte activation and correlation with IMPDH activity under therapy with mycophenolate mofetil.

1 reference

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21 January 2018

Induction of apoptosis in IL-3-dependent hematopoietic cell lines by guanine nucleotide depletion

1 reference

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Apoptosis of superantigen-activated T cells induced by mycophenolate mofetil treatment

1 reference

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21 January 2018

Interpretation of cytokine signaling through the transcription factors STAT5A and STAT5B

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Mycophenolic acid is a potent inhibitor of the expression of tumour necrosis factor‐ and tumour necrosis factor‐receptor superfamily costimulatory molecules

1 reference

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21 January 2018

Unchecked CD70 expression on T cells lowers threshold for T cell activation in rheumatoid arthritis

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CD27 and CD70 in T cell and B cell activation

1 reference

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21 January 2018

Identifiers

10.1111/J.1600-6143.2010.03413.X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21342445%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21342445%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

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