Deletion of the cold thermoreceptor TRPM8 increases heat loss and food intake leading to reduced body temperature and obesity in mice. (Q51245488)

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scientific article published on 12 March 2018

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English	Deletion of the cold thermoreceptor TRPM8 increases heat loss and food intake leading to reduced body temperature and obesity in mice.	scientific article published on 12 March 2018

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scholarly article

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20 March 2020

Deletion of the Cold Thermoreceptor TRPM8 Increases Heat Loss and Food Intake Leading to Reduced Body Temperature and Obesity in Mice (English)

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20 March 2020

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Carlos Fernández-Peña

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20 March 2020

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20 March 2020

Jose L Pardo-Vazquez

7

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20 March 2020

Víctor M. Arce

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20 March 2020

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20 March 2020

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20 March 2020

author name string

Alfonso Reimúndez

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20 March 2020

Guillermo García

3

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20 March 2020

Purificación Ordás

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20 March 2020

Rosalía Gallego

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20 March 2020

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publication date

12 March 2018

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20 March 2020

Journal of Neuroscience

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20 March 2020

38

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20 March 2020

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20 March 2020

3643-3656

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20 March 2020

Fasting respiratory exchange ratio and resting metabolic rate as predictors of weight gain: the Baltimore Longitudinal Study on Aging

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Low ratio of fat to carbohydrate oxidation as predictor of weight gain: study of 24-h RQ.

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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The innervation of the caudal artery of the rat

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Evidence for on-off control of heat dissipation from the tail of the rat.

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Gender differences in physiological reactions to thermal stress

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Food intake as a mechanism of temperature regulation. 1948.

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Temperature-dependent feeding: lack of role for leptin and defect in brown adipose tissue-ablated obese mice

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

based on heuristic

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Obesity: preventing and managing the global epidemic. Report of a WHO consultation

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Effects of estrogen on thermoregulatory tail vasomotion and heat-escape behavior in freely moving female rats

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Identification of a cold receptor reveals a general role for TRP channels in thermosensation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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A TRP channel that senses cold stimuli and menthol

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Effects of fasting on thermoregulatory processes and the daily oscillations in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Lessons from peppers and peppermint: the molecular logic of thermosensation

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Trp ion channels and temperature sensation

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Transient receptor potential ion channels as participants in thermosensation and thermoregulation

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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TRPM8 is required for cold sensation in mice

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Attenuated cold sensitivity in TRPM8 null mice

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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The menthol receptor TRPM8 is the principal detector of environmental cold

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Application of menthol to the skin of whole trunk in mice induces autonomic and behavioral heat-gain responses

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Energy metabolism, fuel selection and body weight regulation

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Circadian timing of food intake contributes to weight gain

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Thermogenesis challenges the adipostat hypothesis for body-weight control.

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Higher 24‐h Respiratory Quotient and Higher Spontaneous Physical Activity in Nighttime Eaters

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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TRPV1-lineage neurons are required for thermal sensation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Central neural pathways for thermoregulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Behavioral thermoregulation in mammals: a review

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Cooling-Sensitive TRPM8 Is Thermostat of Skin Temperature against Cooling

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Scraping through the ice: uncovering the role of TRPM8 in cold transduction

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Pharmacological blockade of TRPM8 ion channels alters cold and cold pain responses in mice

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Activation of the cold-sensing TRPM8 channel triggers UCP1-dependent thermogenesis and prevents obesity

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Pharmacological blockade of the cold receptor TRPM8 attenuates autonomic and behavioral cold defenses and decreases deep body temperature

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Transient receptor potential melastatin 8 (TRPM8) channels are involved in body temperature regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Core temperature: a forgotten variable in energy expenditure and obesity?

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Nighttime snacking reduces whole body fat oxidation and increases LDL cholesterol in healthy young women.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

based on heuristic

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The cellular code for mammalian thermosensation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

based on heuristic

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Enhanced insulin clearance in mice lacking TRPM8 channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Shivering and tachycardic responses to external cooling in mice are substantially suppressed by TRPV1 activation but not by TRPM8 inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

based on heuristic

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Skin temperature: its role in thermoregulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Cosinor-based rhythmometry

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https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Ion channel profile of TRPM8 cold receptors reveals a role of TASK-3 potassium channels in thermosensation

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

based on heuristic

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Leptin signaling is required for adaptive changes in food intake, but not energy expenditure, in response to different thermal conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

based on heuristic

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Integration of body temperature into the analysis of energy expenditure in the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Npvf: Hypothalamic Biomarker of Ambient Temperature Independent of Nutritional Status

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

based on heuristic

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The TRPM2 channel is a hypothalamic heat sensor that limits fever and can drive hypothermia

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Coding and Plasticity in the Mammalian Thermosensory System

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Cold Temperature Encoding by Cutaneous TRPA1 and TRPM8-Carrying Fibers in the Mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Body Temperature Measurements for Metabolic Phenotyping in Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Relevance of TRPA1 and TRPM8 channels as vascular sensors of cold in the cutaneous microvasculature.

1 reference

https://pubmed.ncbi.nlm.nih.gov/29530988

12 December 2020

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Identifiers

10.1523/JNEUROSCI.3002-17.2018

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20 March 2020

PMC publication ID

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29530988%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29530988%20AND%20SRC:MED&resulttype=core&format=json

20 March 2020

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