What We Know and Do Not Know About Actin (Q50475095)

14 March 2018

review article

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title

What We Know and Do Not Know About Actin (English)

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14 March 2018

Thomas D Pollard

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14 March 2018

publication date

22 November 2016

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14 March 2018

Handbook of experimental pharmacology

published in

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14 March 2018

volume

235

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14 March 2018

page(s)

331-347

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14 March 2018

The actin-based nanomachine at the leading edge of migrating cells

cites work

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Identification of a carboxyl-terminal diaphanous-related formin homology protein autoregulatory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Mechanism of actin filament turnover by severing and nucleation at different concentrations of ADF/cofilin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Electrostatic interactions between the Bni1p Formin FH2 domain and actin influence actin filament nucleation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Pathway of actin filament branch formation by Arp2/3 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Structures of actin-like ParM filaments show architecture of plasmid-segregating spindles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Force Feedback Controls Motor Activity and Mechanical Properties of Self-Assembling Branched Actin Networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Mechanism of interaction of Acanthamoeba actophorin (ADF/Cofilin) with actin filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Hydrolysis of ATP by polymerized actin depends on the bound divalent cation but not profilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Structural analysis of the transitional state of Arp2/3 complex activation by two actin-bound WCAs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Single-molecule visualization of a formin-capping protein 'decision complex' at the actin filament barbed end

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Functions of cofilin in cell locomotion and invasion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

A nucleator arms race: cellular control of actin assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Direct evidence for ADP-Pi-F-actin as the major intermediate in ATP-actin polymerization. Rate of dissociation of Pi from actin filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Cofilin dissociates Arp2/3 complex and branches from actin filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Aip1 promotes actin filament severing by cofilin and regulates constriction of the cytokinetic contractile ring

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Kinetic evidence for a monomer activation step in actin polymerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Determinants of Formin Homology 1 (FH1) domain function in actin filament elongation by formins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Interaction of profilin with the barbed end of actin filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Tension modulates actin filament polymerization mediated by formin and profilin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Molecular Dynamics Simulations of Arp2/3 Complex Activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Actin structure and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Capping protein regulators fine-tune actin assembly dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Biophysics of actin filament severing by cofilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Competitive displacement of cofilin can promote actin filament severing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Direct measurement of force generation by actin filament polymerization using an optical trap

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Polymerization of actin: mechanism of the Mg2+-induced process at pH 8 and 20 degrees C

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Direct visualization of secondary structures of F-actin by electron cryomicroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Polymerization kinetics of ADP- and ADP-Pi-actin determined by fluorescence microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Structural polymorphism in F-actin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Saccharomyces cerevisiae Kelch proteins and Bud14 protein form a stable 520-kDa formin regulatory complex that controls actin cable assembly and cell morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Formin proteins: a domain-based approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Individual actin filaments in a microfluidic flow reveal the mechanism of ATP hydrolysis and give insight into the properties of profilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Insertional assembly of actin filament barbed ends in association with formins produces piconewton forces

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

The fission yeast cytokinesis formin Cdc12p is a barbed end actin filament capping protein gated by profilin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Control of the assembly of ATP- and ADP-actin by formins and profilin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

The mouse Formin mDia1 is a potent actin nucleation factor regulated by autoinhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Structural basis for regulation of Arp2/3 complex by GMF

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Characterization of actin filament severing by actophorin from Acanthamoeba castellanii

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Interaction of WASP/Scar proteins with actin and vertebrate Arp2/3 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Unraveling the mystery of ATP hydrolysis in actin filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Cofilin-Linked Changes in Actin Filament Flexibility Promote Severing

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Cofilin Changes the Twist of F-Actin: Implications for Actin Filament Dynamics and Cellular Function

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Coronin Enhances Actin Filament Severing by Recruiting Cofilin to Filament Sides and Altering F-Actin Conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Cell motility driven by actin polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Force generation by actin polymerization II: the elastic ratchet and tethered filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Structural basis for the slow dynamics of the actin filament pointed end

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

The nature of the globular- to fibrous-actin transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Structural basis of actin filament nucleation and processive capping by a formin homology 2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Arp2/3 complex is bound and activated by two WASP proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

How profilin promotes actin filament assembly in the presence of thymosin beta 4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Structure of a Bud6/Actin Complex Reveals a Novel WH2-like Actin Monomer Recruitment Motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

The role of the FH1 domain and profilin in formin-mediated actin-filament elongation and nucleation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Review of the mechanism of processive actin filament elongation by formins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Energetic requirements for processive elongation of actin filaments by FH1FH2-formins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Rate constants for the reactions of ATP- and ADP-actin with the ends of actin filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Cellular motility driven by assembly and disassembly of actin filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Actin, a central player in cell shape and movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Role of formins in actin assembly: nucleation and barbed-end association

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Actin filament curvature biases branching direction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Crystal structure of Arp2/3 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

The structural basis of actin filament branching by the Arp2/3 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Crystal structures of expressed non-polymerizable monomeric actin in the ADP and ATP states

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

The structure of crystalline profilin-beta-actin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Thermodynamics and kinetics of actin filament nucleation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Computer simulations of actin polymerization can explain the barbed-pointed end asymmetry

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Formin and capping protein together embrace the actin filament in a ménage à trois

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Specification of Architecture and Function of Actin Structures by Actin Nucleation Factors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Analysis of the actin-myosin II system in fish epidermal keratocytes: mechanism of cell body translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Actin microfilament dynamics in locomoting cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Structural and biochemical characterization of two binding sites for nucleation-promoting factor WASp-VCA on Arp2/3 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

The structure of the dynactin complex and its interaction with dynein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Model of formin-associated actin filament elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Interactions of Acanthamoeba profilin with actin and nucleotides bound to actin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Structure of the F-actin-tropomyosin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Cortactin promotes and stabilizes Arp2/3-induced actin filament network formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Clathrin-mediated endocytosis in budding yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Effects of profilin and thymosin beta4 on the critical concentration of actin demonstrated in vitro and in cell extracts with a novel direct assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Profilin: emerging concepts and lingering misconceptions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

GMF severs actin-Arp2/3 complex branch junctions by a cofilin-like mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

Formin Leaky Cap Allows Elongation in the Presence of Tight Capping Proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

An actin-binding protein from Acanthamoeba regulates actin filament polymerization and interactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2F164_2016_44

21 January 2018

Identifiers

DOI

10.1007/164_2016_44

1 reference

14 March 2018

1 reference

14 March 2018