Pax6 localizes to chromatin-rich territories and displays a slow nuclear mobility altered by disease mutations. (Q48152943)

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English	Pax6 localizes to chromatin-rich territories and displays a slow nuclear mobility altered by disease mutations.	scientific article

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6 February 2020

Pax6 localizes to chromatin-rich territories and displays a slow nuclear mobility altered by disease mutations (English)

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6 February 2020

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6 February 2020

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6 February 2020

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6 February 2020

author name string

Julianne Elvenes

1

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6 February 2020

Turid Holm

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6 February 2020

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25 June 2010

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6 February 2020

Cellular and Molecular Life Sciences

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6 February 2020

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6 February 2020

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6 February 2020

4079-4094

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6 February 2020

Characterization of quail Pax-6 (Pax-QNR) proteins expressed in the neuroretina

1 reference

https://api.crossref.org/works/10.1007%2FS00018-010-0429-0

21 January 2018

Novel PAX6 binding sites in the human genome and the role of repetitive elements in the evolution of gene regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular linkage between the kinase ATM and NF-kappaB signaling in response to genotoxic stimuli

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional properties of natural human PAX6 and PAX6(5a) mutants

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Conservation of a large protein domain in the segmentation gene paired and in functionally related genes of Drosophila.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid glucocorticoid receptor exchange at a promoter is coupled to transcription and regulated by chaperones and proteasomes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glucocorticoid receptor: rapid exchange with regulatory sites in living cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pax-6, a murine paired box gene, is expressed in the developing CNS

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperative dimerization of paired class homeo domains on DNA.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligand-specific dynamics of the progesterone receptor in living cells and during chromatin remodeling in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Getting your Pax straight: Pax proteins in development and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The third helix of the homeodomain of paired class homeodomain proteins acts as a recognition helix both for DNA and protein interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beyond photobleaching, laser illumination unbinds fluorescent proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PAX-6 in development and evolution

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular determinants of glucocorticoid receptor mobility in living cells: the importance of ligand affinity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nuclear envelope--a scaffold for silencing?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Missense mutation at the C-terminus of PAX6 negatively modulates homeodomain function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PAX6 haploinsufficiency causes cerebral malformation and olfactory dysfunction in humans.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PAX6 mutations: genotype-phenotype correlations

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of alphaA-crystallin via Pax6, c-Maf, CREB and a broad domain of lens-specific chromatin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperative interactions between paired domain and homeodomain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intranuclear mobility of estrogen receptor alpha and progesterone receptors in association with nuclear matrix dynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High resolution crystal structure of a paired (Pax) class cooperative homeodomain dimer on DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ePHD protein SPBP interacts with TopBP1 and together they co-operate to stimulate Ets1-mediated transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction codes within the family of mammalian Phox and Bem1p domain-containing proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential aggregation and functional impairment induced by polyalanine expansions in FOXL2, a transcription factor involved in cranio-facial and ovarian development

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PAX6 suppresses growth of human glioblastoma cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the zebrafish paired box gene pax[zf-b] during early neurogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concise review: Pax6 transcription factor contributes to both embryonic and adult neurogenesis as a multifunctional regulator

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aniridia. A review

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Missense mutations in the DNA-binding region and termination codon in PAX6.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subnuclear localization and mobility are key indicators of PAX3 dysfunction in Waardenburg syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of Pax6 expression using a BAC transgene reveals the presence of a paired-less isoform of Pax6 in the eye and olfactory bulb

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional analysis of paired box missense mutations in the PAX6 gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A hyper-dynamic equilibrium between promoter-bound and nucleoplasmic dimers controls NF-kappaB-dependent gene activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo study of the nucleosome assembly functions of ASF1 histone chaperones in human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific Pax-6/microphthalmia transcription factor interactions involve their DNA-binding domains and inhibit transcriptional properties of both proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Photobleaching GFP reveals protein dynamics inside live cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship between intranuclear mobility of the NF-kappaB subunit p65 and its DNA binding affinity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mobility measurement by analysis of fluorescence photobleaching recovery kinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pax6 induces ectopic eyes in a vertebrate

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Human PAX6 Mutation Database

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PAX6 is expressed in pancreatic cancer and actively participates in cancer progression through activation of the MET tyrosine kinase receptor gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The DNA binding activity of p53 displays reaction-diffusion kinetics.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Compound heterozygosity for mutations in PAX6 in a patient with complex brain anomaly, neonatal diabetes mellitus, and microophthalmia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glucagon gene transcription activation mediated by synergistic interactions of pax-6 and cdx-2 with the p300 co-activator

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PAX6 in sensory development

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nuclear genome organization: common themes and individual patterns

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The androgen receptor ligand-binding domain stabilizes DNA binding in living cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pax genes and eye organogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zebrafish contains two pax6 genes involved in eye development

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The expression of PAX6, PTEN, vascular endothelial growth factor, and epidermal growth factor receptor in gliomas: relationship to tumor grade and survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global methylation pattern of genes in androgen-sensitive and androgen-independent prostate cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evolution and role of Pax genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High- and low-mobility populations of HP1 in heterochromatin of mammalian cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibroblast growth factor receptor-1 (FGFR1) nuclear dynamics reveal a novel mechanism in transcription control

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenotypic variations in patients with a 1630 A>T point mutation in the PAX6 gene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Run-on mutation and three novel nonsense mutations identified in the PAX6 gene in patients with aniridia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hoechst fluorescence pattern of heterochromatin in three closely related members of Drosophila

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a Pax paired domain recognition sequence and evidence for DNA-dependent conformational changes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High mobility of proteins in the mammalian cell nucleus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superactivation of Pax6-mediated transactivation from paired domain-binding sites by dna-independent recruitment of different homeodomain proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scattering of exciting light by live cells in fluorescence confocal imaging: phototoxic effects and relevance for FRAP studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of TATA-binding protein dynamics in living yeast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Homeodomain-DNA recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor suppressor PAX6 functions as androgen receptor co-repressor to inhibit prostate cancer growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymicrogyria and absence of pineal gland due to PAX6 mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivating Pit-1 mutations alter subnuclear dynamics suggesting a protein misfolding and nuclear stress response

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone-GFP fusion protein enables sensitive analysis of chromosome dynamics in living mammalian cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ligand-specific dynamics of the androgen receptor at its response element in living cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nuclear factor SPBP contains different functional domains and stimulates the activity of various transcriptional activators

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SPBP is a phosphoserine-specific repressor of estrogen receptor alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Measurement of dynamic protein binding to chromatin in vivo, using photobleaching microscopy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20577777

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00018-010-0429-0

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20577777%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20577777%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

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