Accumulation of succinimide in a recombinant monoclonal antibody in mildly acidic buffers under elevated temperatures (Q46541519)

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scientific article published on 24 March 2007

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Language	Label	Description	Also known as
English	Accumulation of succinimide in a recombinant monoclonal antibody in mildly acidic buffers under elevated temperatures	scientific article published on 24 March 2007

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instance of

scholarly article

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17385019

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/17385019

title

Accumulation of succinimide in a recombinant monoclonal antibody in mildly acidic buffers under elevated temperatures (English)

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17385019

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/17385019

main subject

antibody

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inferred from title

monoclonal antibody

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based on heuristic

inferred from title

author name string

Grace C Chu

series ordinal

1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17385019

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/17385019

Dirk Chelius

series ordinal

2

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17385019

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/17385019

Gang Xiao

series ordinal

3

1 reference

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Europe PubMed Central

PubMed publication ID

17385019

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/17385019

Hui K Khor

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4

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Europe PubMed Central

PubMed publication ID

17385019

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/17385019

Sururat Coulibaly

series ordinal

5

1 reference

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Europe PubMed Central

PubMed publication ID

17385019

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/17385019

Pavel V Bondarenko

series ordinal

6

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Europe PubMed Central

PubMed publication ID

17385019

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/17385019

publication date

24 March 2007

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stated in

Europe PubMed Central

PubMed publication ID

17385019

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/17385019

published in

Pharmaceutical Research

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17385019

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/17385019

volume

24

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stated in

Europe PubMed Central

PubMed publication ID

17385019

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/17385019

issue

6

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17385019

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/17385019

page(s)

1145-1156

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Europe PubMed Central

PubMed publication ID

17385019

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/17385019

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A failure to repair self-proteins leads to T cell hyperproliferation and autoantibody production

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Intracellular protein modification associated with altered T cell functions in autoimmunity

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Characterization of a beta-Asp33 isoform of recombinant hirudin sequence variant 1 by low-energy collision-induced dissociation.

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12 December 2020

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Chemical pathways of peptide degradation. IV. Pathways, kinetics, and mechanism of degradation of an aspartyl residue in a model hexapeptide

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17385019

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12 December 2020

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Structure and evolution of immunoglobulins

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17385019

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12 December 2020

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Characterization, formulation, and stability of Neupogen (Filgrastim), a recombinant human granulocyte-colony stimulating factor.

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12 December 2020

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De novo peptide sequencing based on a divide-and-conquer algorithm and peptide tandem spectrum simulation

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17385019

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12 December 2020

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Prediction of low-energy collision-induced dissociation spectra of peptides

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17385019

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12 December 2020

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Analysis of isoaspartate in a recombinant monoclonal antibody and its charge isoforms

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17385019

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of multiple sources of charge heterogeneity in a recombinant antibody.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17385019

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversed-phase liquid chromatography/mass spectrometry analysis of reduced monoclonal antibodies in pharmaceutics

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17385019

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isomerization of an aspartic acid residue in the complementarity-determining regions of a recombinant antibody to human IgE: identification and effect on binding affinity.

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17385019

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improving mass accuracy of high performance liquid chromatography/electrospray ionization time-of-flight mass spectrometry of intact antibodies

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17385019

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence-specific deamidation: isolation and biochemical characterization of succinimide intermediates of recombinant hirudin.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17385019

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Succinimide formation from aspartyl and asparaginyl peptides as a model for the spontaneous degradation of proteins

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17385019

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of the isomerization of Asp residue in recombinant human alpha A-crystallin by reversed-phase HPLC.

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17385019

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12 December 2020

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Molecular aging of tubulin: accumulation of isoaspartyl sites in vitro and in vivo

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17385019

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12 December 2020

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Identification and characterization of deamidation sites in the conserved regions of human immunoglobulin gamma antibodies

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17385019

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isoaspartate in peptides and proteins: formation, significance, and analysis

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17385019

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of 101-succinimide lysozyme that possesses the cyclic imide at Asp101-Gly102

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17385019

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Optimization of a reversed-phase high-performance liquid chromatography/mass spectrometry method for characterizing recombinant antibody heterogeneity and stability

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17385019

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antioxidants for Prevention of Methionine Oxidation in Recombinant Monoclonal Antibody HER2

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/17385019

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12 December 2020

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inferred from PubMed ID database lookup

Incorporation of two 18O atoms into a peptide during isoaspartyl repair reveals repeated passage through a succinimide intermediate

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17385019

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Site-specific conjugation on serine right-arrow cysteine variant monoclonal antibodies

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PubMed

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12 December 2020

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inferred from PubMed ID database lookup

Formation of pyroglutamic acid from N-terminal glutamic acid in immunoglobulin gamma antibodies

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PubMed

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12 December 2020

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Isoaspartyl post-translational modification triggers anti-tumor T and B lymphocyte immunity.

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PubMed

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retrieved

12 December 2020

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Isolation and characterization of a succinimide variant of methionyl human growth hormone

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17385019

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deamidation, isomerization, and racemization at asparaginyl and aspartyl residues in peptides. Succinimide-linked reactions that contribute to protein degradation

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17385019

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stabilization of lysozyme against irreversible inactivation by alterations of the Asp-Gly sequences

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/17385019

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/S11095-007-9241-4

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17385019

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/17385019

PubMed publication ID

17385019

1 reference

stated in

Europe PubMed Central

PubMed publication ID

17385019

retrieved

23 December 2017

reference URL

http://europepmc.org/abstract/MED/17385019

 

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