Etazolate, a neuroprotective drug linking GABA(A) receptor pharmacology to amyloid precursor protein processing (Q46240526)

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scientific article published in July 2008

Language	Label	Description	Also known as
English	Etazolate, a neuroprotective drug linking GABA(A) receptor pharmacology to amyloid precursor protein processing	scientific article published in July 2008

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/18397369

Etazolate, a neuroprotective drug linking GABA(A) receptor pharmacology to amyloid precursor protein processing (English)

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/18397369

1 reference

ChEBI release 2020-05-28

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based on heuristic

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author name string

Maryline Marcade

1

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/18397369

Jérôme Bourdin

2

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/18397369

Nadia Loiseau

3

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/18397369

Hélène Peillon

4

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/18397369

Aurélie Rayer

5

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/18397369

Dominique Drouin

6

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/18397369

Fabien Schweighoffer

7

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/18397369

Laurent Désiré

8

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/18397369

language of work or name

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publication date

1 July 2008

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/18397369

Journal of Neurochemistry

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Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/18397369

106

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/18397369

1

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/18397369

392-404

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/18397369

BACE1- and BACE2-expressing human cells: characterization of beta-amyloid precursor protein-derived catabolites, design of a novel fluorimetric assay, and identification of new in vitro inhibitors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Role of the APP non-amyloidogenic signaling pathway and targeting alpha-secretase as an alternative drug target for treatment of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Guinea pigs as a nontransgenic model for APP processing in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

The amyloid pathology progresses in a neurotransmitter-specific manner

1 reference

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21 January 2018

Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo

1 reference

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21 January 2018

Enigmatic GABAergic networks in adult neurogenic zones

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Soluble form of amyloid precursor protein regulates proliferation of progenitors in the adult subventricular zone.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

sAPPalpha enhances the transdifferentiation of adult bone marrow progenitor cells to neuronal phenotypes.

1 reference

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21 January 2018

ERK1/2 activation mediates Abeta oligomer-induced neurotoxicity via caspase-3 activation and tau cleavage in rat organotypic hippocampal slice cultures

1 reference

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21 January 2018

Acute gamma-secretase inhibition improves contextual fear conditioning in the Tg2576 mouse model of Alzheimer's disease.

1 reference

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21 January 2018

An inverse agonist selective for alpha5 subunit-containing GABAA receptors enhances cognition.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

RAC1 inhibition targets amyloid precursor protein processing by gamma-secretase and decreases Abeta production in vitro and in vivo.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Tumor necrosis factor-alpha converting enzyme is processed by proprotein-convertases to its mature form which is degraded upon phorbol ester stimulation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Increase in extracellular NCAM and amyloid precursor protein following induction of long-term potentiation in the dentate gyrus of anaesthetized rats

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Activation of muscarinic receptors inhibits beta-amyloid peptide-induced signaling in cortical slices

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Involvement of c-Jun N-terminal kinase in amyloid precursor protein-mediated neuronal cell death.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Synaptic changes in Alzheimer's disease: increased amyloid-beta and gliosis in surviving terminals is accompanied by decreased PSD-95 fluorescence

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Furin is an endogenous regulator of alpha-secretase associated APP processing

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Acceleration of amyloid beta-peptide aggregation by physiological concentrations of calcium

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

APP processing and synaptic function

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

A neural cell adhesion molecule-derived peptide reduces neuropathological signs and cognitive impairment induced by Abeta25-35.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Decreased α-secretase-cleaved amyloid precursor protein as a diagnostic marker for Alzheimer's diseas

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Chronic stimulation of GABAA receptor with muscimol reduces amyloid beta protein (25-35)-induced neurotoxicity in cultured rat cortical cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Neuroprotection by D-securinine against neurotoxicity induced by beta-amyloid (25-35).

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Taurine prevents the neurotoxicity of beta-amyloid and glutamate receptor agonists: activation of GABA receptors and possible implications for Alzheimer's disease and other neurological disorders

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Crosstalk between Rap1 and Rac regulates secretion of sAPPalpha

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Synapse-associated protein-97 mediates alpha-secretase ADAM10 trafficking and promotes its activity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Evidence for excitoprotective and intraneuronal calcium-regulating roles for secreted forms of the beta-amyloid precursor protein

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Memory-enhancing effects of secreted forms of the beta-amyloid precursor protein in normal and amnestic mice.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Molecular regulation of cognitive functions and developmental plasticity: impact of GABAA receptors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Enhancement of working memory performance in the rat by MDL 26,479, a novel compound with activity at the GABAA receptor complex.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Functional modulation of GABAA receptors by cAMP-dependent protein phosphorylation

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Alpha- and beta-secretase activity as a function of age and beta-amyloid in Down syndrome and normal brain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Release of amyloid beta-protein precursor derivatives by electrical depolarization of rat hippocampal slices

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Regulation of APP cleavage by alpha-, beta- and gamma-secretases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Pharmacology of pyrazolopyridines

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Regulation of the amyloid precursor protein ectodomain shedding by the 5-HT4 receptor and Epac.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

A monoclonal antibody to amyloid precursor protein induces neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

GABA receptors ameliorate Hcy-mediated integrin shedding and constrictive collagen remodeling in microvascular endothelial cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Amyloid beta peptide adversely affects spine number and motility in hippocampal neurons.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Neutralization of transthyretin reverses the neuroprotective effects of secreted amyloid precursor protein (APP) in APPSW mice resulting in tau phosphorylation and loss of hippocampal neurons: support for the amyloid hypothesis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Tracazolate reveals a novel type of allosteric interaction with recombinant gamma-aminobutyric acid(A) receptors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Roles of amyloid precursor protein and its fragments in regulating neural activity, plasticity and memory

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Cholesterol-dependent gamma-secretase activity in buoyant cholesterol-rich membrane microdomains

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Expression, purification, and characterization of human cAMP-specific phosphodiesterase (PDE4) subtypes A, B, C, and D.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

A Novel γ-Secretase Assay Based on Detection of the Putative C-terminal Fragment-γ of Amyloid β Protein Precursor

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2008.05396.X

21 January 2018

Identifiers

10.1111/J.1471-4159.2008.05396.X

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/18397369

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

20 December 2017

http://europepmc.org/abstract/MED/18397369

ResearchGate publication ID

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