64Cu-MM-302 Positron Emission Tomography Quantifies Variability of Enhanced Permeability and Retention of Nanoparticles in Relation to Treatment Response in Patients with Metastatic Breast Cancer. (Q46097998)

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scientific article published on 15 March 2017

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English	64Cu-MM-302 Positron Emission Tomography Quantifies Variability of Enhanced Permeability and Retention of Nanoparticles in Relation to Treatment Response in Patients with Metastatic Breast Cancer.	scientific article published on 15 March 2017

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scholarly article

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Europe PubMed Central

PubMed publication ID

19 December 2017

http://europepmc.org/abstract/MED/28298546

64Cu-MM-302 Positron Emission Tomography Quantifies Variability of Enhanced Permeability and Retention of Nanoparticles in Relation to Treatment Response in Patients with Metastatic Breast Cancer (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6790129&resulttype=core&format=json

12 May 2020

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positron emission tomography

1 reference

based on heuristic

inferred from title

Dmitri B. Kirpotin

14

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12 May 2020

Kathy D. Miller

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Kathy D Miller

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12 May 2020

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Helen Lee

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Anthony F Shields

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Barry A Siegel

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Ian Krop

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Cynthia X Ma

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Patricia M LoRusso

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Pamela N Munster

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Karen Campbell

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Daniel F Gaddy

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Shannon C Leonard

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Elena Geretti

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Stephanie J Blocker

13

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12 May 2020

Victor Moyo

15

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Thomas J Wickham

16

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12 May 2020

Bart S Hendriks

17

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12 May 2020

language of work or name

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publication date

15 March 2017

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19 December 2017

http://europepmc.org/abstract/MED/28298546

Clinical Cancer Research

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12 May 2020

23

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12 May 2020

15

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12 May 2020

4190-4202

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6790129&resulttype=core&format=json

12 May 2020

Nanoreporter PET predicts the efficacy of anti-cancer nanotherapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

12 December 2020

based on heuristic

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First-line chemotherapy with liposomal doxorubicin plus cisplatin for patients with advanced malignant pleural mesothelioma: phase II trial.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclophosphamide-Mediated Tumor Priming for Enhanced Delivery and Antitumor Activity of HER2-Targeted Liposomal Doxorubicin (MM-302).

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual HER2 Targeting with Trastuzumab and Liposomal-Encapsulated Doxorubicin (MM-302) Demonstrates Synergistic Antitumor Activity in Breast and Gastric Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Liposome-mediated therapy of intracranial brain tumors in a rat model

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Efficient tumor targeting of hydroxycamptothecin loaded PEGylated niosomes modified with transferrin

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

12 December 2020

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Challenges and key considerations of the enhanced permeability and retention effect for nanomedicine drug delivery in oncology

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

12 December 2020

based on heuristic

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Targeted drug delivery to tumors: Myths, reality and possibility

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

12 December 2020

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Imaging nanoprobe for prediction of outcome of nanoparticle chemotherapy by using mammography.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

12 December 2020

based on heuristic

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Positron Emission Tomography Based Elucidation of the Enhanced Permeability and Retention Effect in Dogs with Cancer Using Copper-64 Liposomes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regional blood flow, capillary permeability, and compartmental volumes: measurement with dynamic CT--initial experience

1 reference

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Developing and testing integrated multicompartment models to describe a single-input multiple-output study using the SAAM II software system

1 reference

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Predicting chemotherapy response to paclitaxel with 18F-Fluoropaclitaxel and PET.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

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Determinants of tumor blood flow: a review

1 reference

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Breast cancer: regional blood flow and blood volume measured with magnetic susceptibility-based MR imaging--initial results

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

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Dose dependency of pharmacokinetics and therapeutic efficacy of pegylated liposomal doxorubicin (DOXIL) in murine models

1 reference

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Doxorubicin encapsulated in sterically stabilized liposomes for the treatment of a brain tumor model: biodistribution and therapeutic efficacy

1 reference

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Quantitative CT imaging of the spatial and temporal distribution of liposomes in a rabbit tumor model

1 reference

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A modeling analysis of the effects of molecular size and binding affinity on tumor targeting

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https://pubmed.ncbi.nlm.nih.gov/28298546

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64Cu-DOTA-trastuzumab PET imaging in patients with HER2-positive breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

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based on heuristic

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High intratumoural accumulation of stealth liposomal doxorubicin (Caelyx) in glioblastomas and in metastatic brain tumours

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

12 December 2020

based on heuristic

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Does a targeting ligand influence nanoparticle tumor localization or uptake?

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Biodistribution of 89Zr-trastuzumab and PET imaging of HER2-positive lesions in patients with metastatic breast cancer

1 reference

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A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs

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Nanoparticle PEGylation for Imaging and Therapy

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High intratumoral accumulation of stealth liposomal doxorubicin in sarcomas--rationale for combination with radiotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

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Enhanced permeability and retention of macromolecular drugs in solid tumors: a royal gate for targeted anticancer nanomedicines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

12 December 2020

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A gradient-loadable (64)Cu-chelator for quantifying tumor deposition kinetics of nanoliposomal therapeutics by positron emission tomography

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

12 December 2020

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Heterogeneous Blood–Tumor Barrier Permeability Determines Drug Efficacy in Experimental Brain Metastases of Breast Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

12 December 2020

based on heuristic

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OLINDA/EXM: the second-generation personal computer software for internal dose assessment in nuclear medicine

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

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based on heuristic

inferred from PubMed ID database lookup

Nanomedicine for drug targeting: strategies beyond the enhanced permeability and retention effect

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Whole-body organ-level and kidney micro-dosimetric evaluations of (64)Cu-loaded HER2/ErbB2-targeted liposomal doxorubicin ((64)Cu-MM-302) in rodents and primates.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

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inferred from PubMed ID database lookup

Physical models and dose factors for use in internal dose assessment

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https://pubmed.ncbi.nlm.nih.gov/28298546

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inferred from PubMed ID database lookup

Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28298546

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Antibody Targeting of Long-Circulating Lipidic Nanoparticles Does Not Increase Tumor Localization but Does Increase Internalization in Animal Models

1 reference

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Odyssey of a cancer nanoparticle: from injection site to site of action

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Toward a full understanding of the EPR effect in primary and metastatic tumors as well as issues related to its heterogeneity

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Biodistribution of monoclonal antibodies: scale-up from mouse to human using a physiologically based pharmacokinetic model

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https://pubmed.ncbi.nlm.nih.gov/28298546

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based on heuristic

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Multiscale kinetic modeling of liposomal Doxorubicin delivery quantifies the role of tumor and drug-specific parameters in local delivery to tumors

1 reference

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Biodistribution and predictive value of 18F-fluorocyclophosphamide in mice bearing human breast cancer xenografts

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Macromolecular therapeutics in cancer treatment: the EPR effect and beyond

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Nanoparticle ligand presentation for targeting solid tumors

1 reference

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based on heuristic

inferred from PubMed ID database lookup

High liposomal doxorubicin tumour tissue distribution, as determined by radiopharmaceutical labelling with (99m)Tc-LD, is associated with the response and survival of patients with unresectable pleural mesothelioma treated with a combination of lipo

1 reference

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1 reference

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1 reference

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HER2-targeted liposomal doxorubicin displays enhanced anti-tumorigenic effects without associated cardiotoxicity

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Identifiers

10.1158/1078-0432.CCR-16-3193

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6790129&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6790129&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6790129&resulttype=core&format=json

12 May 2020

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